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11.发明申请PNEUMATIC NEBULIZING INTERFACE, METHOD FOR MAKING AND USING SAME AND INSTRUMENTS INCLUDING SAME 审中-公开气动接触界面，制造和使用它们的方法和包括其的仪器
公开(公告)号：WO01003848A1
公开(公告)日：2001-01-18
申请号：PCT/US2000/019020
申请日：2000-07-12
IPC: G01N27/62 , B05B7/04 , B05B7/06 , G01N1/00 , G01N21/76 , G01N27/447 , G01N30/72 , G01N30/84 , G01N31/12 , G01N35/08
CPC classification number: G01N27/44717 , B05B7/0408 , B05B7/064 , B05B7/066 , G01N1/22 , G01N31/12 , G01N35/085 , G01N2030/8464 , G01N2030/847 , H01J49/045 , Y10T436/117497 , Y10T436/119163 , Y10T436/20 , Y10T436/24 , Y10T436/25
Abstract: A self-adjusting, free-flowing pneumatic nebulizer interface (10) is described for coupling fluid phase separation apparatus such as capillary electrophoresis apparatus or fluid-phase analyte delivery apparatus such as flow-injection analysis apparatus to gas phase, post-separation detection apparatus such as mass spectrometers, chemiluminescence detectors, or other similar gas phase detection apparatus. The interface combines the analytes (12) with only the needed amount of sheath fluid (22) to produce a combined flow (32) whose magnitude automatically matches the self-aspiration rate of the pneumatic nebulizer interface, and which is combined with a gas flow (52) to produce an aerosol (58). The resulting aerosol can then be either deposited directly on a surface, forwarded directly to a detection system or forwarded first to a conversion apparatus such as an oxidizer and the oxidized sample components are then forwarded to a detector.
Abstract translation: 描述了一种自调节自由流动的气动雾化器接口（10），用于将流动相分离装置如毛细管电泳装置或流体相分析物输送装置如流动注射分析装置耦合到气相，分离后检测装置 例如质谱仪，化学发光检测器或其它类似的气相检测装置。 界面将分析物（12）与仅需要量的鞘液（22）组合以产生组合流（32），其大小自动匹配气动雾化器界面的自吸气速率，并与气流 （52）以产生气溶胶（58）。 所得到的气溶胶然后可以直接沉积在表面上，直接转发到检测系统或首先转发到诸如氧化剂的转化装置，然后将氧化的样品组分转发到检测器。
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12.发明申请SUBATMOSPHERIC, VARIABLE PRESSURE SAMPLE DELIVERY CHAMBER FOR ELECTROSPRAY IONIZATION/MASS SPECTROMETRY AND OTHER APPLICATIONS 审中-公开用于电喷雾离子/质谱分析和其他应用的可变压力样品输送室
公开(公告)号：WO1997026072A1
公开(公告)日：1997-07-24
申请号：PCT/US1997000733
申请日：1997-01-17
Applicant: NORTHEASTERN UNIVERSITY
Inventor： NORTHEASTERN UNIVERSITY , KARGER, Barry, L. , FORET, Frantisek , KIRBY, Daniel, P.
IPC: B01D59/44
CPC classification number: H01J49/045 , G01N27/44717 , G01N30/7266 , G01N2030/285 , H01J49/165
Abstract: A subatmospheric, variable pressure sample delivery chamber (2), useful as an electrospray ionization device for introducing a sample into a mass spectrometer (9) or as a sample device at subatmospheric pressures, is disclosed. The sample delivery chamber (2) is configured to maintain an operating pressure between 1 and 750 Torr, preferably between 50 and 700 Torr. The chamber has an inlet port (4) for introduction of a gas and an exit port (6) capable of being coupled either to a sampling orifice (8) for an analytical device, usually a mass spectrometer (9), or directly to a pump for removal of gas. A sample delivery device (22) is capable of receiving a sample and the exit port (6) of the chamber, if the sample is to be delivered to an external analytical device, or aligned with the collection device, for direct collection of the sample.
Abstract translation: 公开了一种低于大气压的可变压力样品输送室（2），其用作将样品引入质谱仪（9）或作为低于大气压的样品装置的电喷雾离子化装置。 样品输送室（2）被构造成将操作压力保持在1和750托之间，优选在50和700托之间。 腔室具有用于引入气体的入口（4）和能够耦合到用于分析装置（通常为质谱仪（9））的采样孔（8）的出口（6），或直接连接到 泵用于除气。 样品输送装置（22）能够接收样品和室的出口（6），如果要将样品输送到外部分析装置或与收集装置对准，以便直接收集样品 。
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公开(公告)号：KR1020160125478A
公开(公告)日：2016-10-31
申请号：KR1020167026287
申请日：2015-02-27
Applicant: 엘리멘탈 사이언티픽, 인코포레이티드
CPC classification number: G01N1/10 , G01N1/14 , G01N35/00732 , G01N35/00871 , G01N35/1097 , G01N2001/002 , H01J49/045
Abstract: 시스템은제1 위치에있는분석시스템및 제1 위치로부터이격한제2 위치에있는하나이상의원격샘플링시스템을포함한다. 샘플링시스템은원격액체샘플을수용하도록구성될수 있다. 시스템은제2 위치로부터제1 위치로가스를운반하도록구성된샘플이송라인을또한포함한다. 샘플이송라인은연속적인액체샘플세그먼트를샘플이송라인에공급하기위해원격샘플링시스템과선택적으로결합하도록구성된다. 시스템은제1 위치에있는샘플수용라인을더 포함할수 있다. 샘플수용라인은샘플이송라인및 분석시스템과선택적으로결합되어연속적인액체샘플세그먼트를수용하고샘플을분석디바이스에공급한다.
Abstract translation: 系统包括在第一位置处的分析系统和在远离第一位置的第二位置处的一个或多个远程采样系统。 采样系统可以被配置为接收远程液体样品。 该系统还包括被配置为将气体从第二位置输送到第一位置的样品传送管线。 样品传输线被配置为选择性地与远程采样系统耦合，以将连续的液体样品段供应到样品传送线。 该系统还可以包括在第一位置处的样本接收线。 样品接收管线被配置为选择性地与样品输送管线和分析系统结合以接收连续液体样品段并将样品供应到分析装置。
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公开(公告)号：KR1020170028403A
公开(公告)日：2017-03-13
申请号：KR1020177003062
申请日：2015-07-21
Applicant: 가부시키가이샤 이아스 , 신에쯔 한도타이 가부시키가이샤
CPC classification number: G01N27/62 , B01L3/021 , B01L3/0262 , B01L3/0293 , B01L2200/0684 , B01L2200/082 , G01N1/00 , G01N1/28 , G01N1/32 , G01N35/10 , G01N35/1002 , G01N35/1016 , G01N35/1095 , H01J49/045 , H01J49/105
Abstract: 본발명은 ICP-MS에의한기판의국소분석을자동화한분석장치의제공을과제로한다. 본발명은기판상으로분석액을토출하는분석액공급수단, 분석대상물을포함하는분석액을기판상으로부터노즐내로회수하여네뷸라이저로송액하는분석액배출수단및 노즐내를배기경로로하는배기수단을갖는국소분석용노즐을구비하고, 회수한분석액을 ICP-MS로자동적으로송액하는자동송액수단을가지며, 분석액유량을조정하는유량조정수단을갖고, 국소분석과 ICP-MS에의한분석대상물의분석을동시진행으로행하여인접한복수의소정영역을연속해서자동분석하는자동제어수단을갖는기판국소의자동분석장치에관한것이다.
Abstract translation: 本发明的目的是提供一种自动化使用ICP-MS的局部衬底分析的分析装置。 本发明涉及一种具有用于局部分析的喷嘴的自动局部基板分析装置，其具有用于将分析液体排放到基板上的分析液体供应装置，用于将分析液体收集在基板上的分析液体排出装置， 分析对象，喷嘴并将分析液体送到雾化器，以及具有喷嘴内部作为排气路径的排气装置，并具有自动液体传输装置，用于将收集的分析液体自动传送到ICP- MS，用于调节分析液体的流量的流量调节装置，以及同时对分析对象进行局部分析和ICP-MS分析并自动顺序分析多个相邻规定区域的自动控制装置。
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公开(公告)号：KR1020110076224A
公开(公告)日：2011-07-06
申请号：KR1020090132875
申请日：2009-12-29
Applicant: 한국기초과학지원연구원
CPC classification number: H01J49/165 , H01J49/045
Abstract: PURPOSE: An electrospray ionization apparatus and an electrospray ionization method using the same are provided to minimizing the diffusion of ions occurred through an electrospray ionization process. CONSTITUTION: An electrospray ionization apparatus comprises a platform(10), a nebulizer(20), and a focusing lens(30). The platform comprises an inlet(110), first and second channels, and an outlet(123). The first channel is connected to the inlet. The second channel is connected to the first channel. The outlet is connected to the second channel. The nebulizer is located at the inside the first channel and nebulizes inert gas to samples sprayed on the first channel. The condensing lens is located at the inside the second channel and focus ions generated from the sprayed samples toward the outlet.
Abstract translation: 目的：提供电喷雾离子化装置和使用其的电喷雾离子化方法以使通过电喷雾电离过程发生的离子的扩散最小化。 构成：电喷雾离子化装置包括平台（10），喷雾器（20）和聚焦透镜（30）。 平台包括入口（110），第一和第二通道以及出口（123）。 第一个通道连接到入口。 第二个通道连接到第一个通道。 插座连接到第二个通道。 喷雾器位于第一通道的内部，并将喷雾在第一通道上的样品的惰性气体喷雾。 聚光透镜位于第二通道的内部，并将从喷射样品产生的离子聚焦到出口。
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Patent Agency Ranking
公开(公告)号：KR101089328B1
公开(公告)日：2011-12-02
申请号：KR1020090132875
申请日：2009-12-29
Applicant: 한국기초과학지원연구원
CPC classification number: H01J49/165 , H01J49/045
Abstract: 전기분무 이온화(electrospray ionization) 장치는, 주입구, 상기 주입구에 연결되는 제1 채널, 상기 제1 채널에 연결되는 제2 채널 및 상기 제2 채널에 연결되는 유출구를 포함하는 플랫폼; 상기 제1 채널 내에 위치하며, 상기 주입구를 통해 상기 제1 채널 내에 분사되는 시료에 비활성 기체를 분사하는 기체 연무기; 및 상기 제2 채널 내에 위치하며, 분사된 시료로부터 생성된 이온들을 상기 유출구 방향으로 집속하는 집속 렌즈를 포함할 수 있다. 전기분무 이온화 방법은, 상기 전기분무 이온화 장치를 이용하여 수행되며, 상기 주입구를 통하여 상기 제1 채널 내에 액체 시료를 분사하는 단계; 분사된 시료에 상기 기체 연무기를 이용하여 비활성 기체를 분사하는 단계; 및 시료로부터 생성된 이온들을 상기 집속 렌즈를 이용하여 상기 유출구 방향으로 집속시키는 단계를 포함할 수 있다.
전기분무, 이온화, ESI, 질량분석기, 액체크로마토그래피, LC-MS-
公开(公告)号：KR101921840B1
公开(公告)日：2018-11-23
申请号：KR1020177003062
申请日：2015-07-21
Applicant: 가부시키가이샤 이아스 , 신에쯔 한도타이 가부시키가이샤
CPC classification number: G01N27/62 , B01L3/0203 , B01L3/021 , B01L3/0262 , B01L3/0293 , B01L2200/0684 , B01L2200/082 , B01L2400/022 , G01N1/00 , G01N1/28 , G01N1/32 , G01N35/10 , G01N35/1002 , G01N35/1016 , G01N35/1095 , H01J49/045 , H01J49/105
Abstract: 본발명은 ICP-MS에의한기판의국소분석을자동화한분석장치의제공을과제로한다. 본발명은기판상으로분석액을토출하는분석액공급수단, 분석대상물을포함하는분석액을기판상으로부터노즐내로회수하여네뷸라이저로송액하는분석액배출수단및 노즐내를배기경로로하는배기수단을갖는국소분석용노즐을구비하고, 회수한분석액을 ICP-MS로자동적으로송액하는자동송액수단을가지며, 분석액유량을조정하는유량조정수단을갖고, 국소분석과 ICP-MS에의한분석대상물의분석을동시진행으로행하여인접한복수의소정영역을연속해서자동분석하는자동제어수단을갖는기판국소의자동분석장치에관한것이다.
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公开(公告)号：JP2017526131A
公开(公告)日：2017-09-07
申请号：JP2017509769
申请日：2015-08-18
Applicant: マイクロマス ユーケー リミテッド , マイクロマス ユーケー リミテッド
Inventor： ステバン・バジック
CPC classification number: H01J49/045 , H01J49/16
Abstract: イオン源であって、1つ以上のネブライザ(1)及び1つ以上のターゲット(50)を備え、前記1つ以上のネブライザ(1)が、使用中に前記1つ以上のターゲット(50)に衝突させられる主として液滴の流れを放出するように、かつ複数のイオンを生成するべく前記液滴をイオン化するように、配置及び適合され、前記1つ以上のターゲット(50)が、前記1つ以上のターゲット(50)の表面に沿って流れるガスを乱すように構成された1つ以上の構造体(14)をさらに備える、イオン源が提供される。
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19.发明专利Atomizer for analyzer which performs analysis by ionizing or atomizing sample using plasma and analyzer 有权通过使用等离子体和分析仪离子化或使样品进行分析的分析仪的分析仪
公开(公告)号：JP2013130492A
公开(公告)日：2013-07-04
申请号：JP2011280713
申请日：2011-12-22
Applicant: National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所 , St Japan Inc , 株式会社エス・テイ・ジャパン
Inventor： INAGAKI KAZUMI , FUJII SHINICHIRO , TAKATSU AKIKO , CHIBA KOICHI , NAKAGAWA TAKAO , ABE MASAAKI , KITAGAWA NOBUYOSHI , NAKAGAWA YOSUKE
CPC classification number: H01J49/105 , B05B7/0416 , G01J3/443 , G01N21/714 , H01J49/045
Abstract: PROBLEM TO BE SOLVED: To provide an atomizer capable of reducing residue of sample liquid in a nebulizer while uniformly miniaturizing a particle size of a droplet atomized at wide sample liquid flow rates.SOLUTION: An atomizer 3 includes: an inner cylinder 12 which is arranged coaxially with an outer cylinder 11 where a spray port 11a is formed, and forms a gas passage R1 with the outer cylinder 11; a sample passage R2 which is formed inside the inner cylinder 12, and through which a liquid sample to be atomized flows; and a net-like member 27 which is arranged with a gap from a sample exit 12a formed at one end of the inner cylinder 12 and has a plurality of holes formed such that the liquid sample in a drop shape which flows out from the sample exit 12a passes through the holes together with a gas.
Abstract translation: 要解决的问题：提供能够减少喷雾器中的样品液体残留物的雾化器，同时使在宽样品液体流速下雾化的液滴的粒径均匀地小型化。解决方案：雾化器3包括：内筒12，其布置 与形成有喷射口11a的外筒11同轴，并与外筒11形成气体通道R1; 形成在内筒12内部的待雾化的液体样品流过的样品通道R2; 以及网状构件27，其与形成在内筒12的一端的样品出口12a间隔设置有多个孔，其形成为从样品出口流出的液滴样品 12a与气体一起通过孔。
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公开(公告)号：JP3581604B2
公开(公告)日：2004-10-27
申请号：JP25847099
申请日：1999-09-13
Applicant: 株式会社日立製作所
Inventor： 義昭 加藤
CPC classification number: H01J49/165 , H01J49/045
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