Process for the preparation of cinnamic acids which are optionally
substituted in the nucleus
    202.
    发明授权
    Process for the preparation of cinnamic acids which are optionally substituted in the nucleus 失效
    在核中任选取代的肉桂酸的制备方法

    公开(公告)号:US4613692A

    公开(公告)日:1986-09-23

    申请号:US743254

    申请日:1985-06-11

    CPC classification number: C07C51/353

    Abstract: A process for the preparation of cinnamic acid is provided by the present invention in which an optionally substituted benzaldehyde and alkali metal salt of carboxylic acid and/or alkali metal (bi) carbonate, as condensing agents, are heated up to a temperature of 100.degree.-220.degree. C. and thereafter there is introduced into the so heated mixture acetic anhydride in at least a stoichiometric amount based upon the amount of optionally substituted benzaldehyde employed. The process can be carried out by heating up a reaction mixture to 100.degree.-220.degree. C. which is free of acetic anhydride or one which contains acetic anhydride but less than a stoichiometric amount thereof based upon the amount of optionally substituted benzaldehyde.

    Abstract translation: 通过本发明提供了制备肉桂酸的方法,其中将任选取代的苯甲醛和羧酸和/或碱金属(bi)碳酸盐的碱金属盐作为缩合剂加热至100℃ -220℃,然后基于所使用的任选取代的苯甲醛的量,以至少化学计量的量将如此加热的混合物乙酸酐引入。 该方法可以通过将反应混合物加热至不含乙酸酐的100℃-220℃或基于任选取代的苯甲醛的量而含有乙酸酐但少于其化学计量的反应混合物进行。

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