公开(公告)号：EP2929308A1

公开(公告)日：2015-10-14

申请号：EP13860485.5

申请日：2013-12-05

Applicant: Genepoc Inc. ,  Université Laval

Inventor： LEMIEUX, Hugo ,  CHAPDELAINE, Sébastien ,  BÉLIVEAU-VIEL, David ,  GRAVEL, Jean-François

IPC: G01J3/443 ,  C12M1/34 ,  G01J3/10 ,  G01J3/12 ,  G01N21/07 ,  C12M1/38

CPC classification number: G01N21/6486 ,  G01J3/021 ,  G01J3/0213 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/443 ,  G01J2003/102 ,  G01N21/6408 ,  G01N21/6445 ,  G01N21/645 ,  G01N21/763 ,  G01N2021/6419 ,  G01N2021/6471 ,  G01N2021/6484 ,  G01N2201/061

Abstract: An interrogation device for detecting luminescent light produced by analytes in a sample excited by multiple excitation light beams each having individual spectral contents, comprising a plurality of light sources each generating an excitation light beam; at least one detector for detecting the luminescent light produced by the sample; and an optical assembly defining distinct and fixed excitation light paths for each of the excitation light beams from the light sources to a common excitation site on the sample and defining a shared luminescence light path for the luminescent light from the excitation site on sample to the at least one detector, the excitation light paths and the luminescence light path being on a same side of the sample, the optical assembly including sample-side optics projecting the excitation light towards the sample and collecting luminescent light from the sample.

Abstract translation: 一种询问装置，用于检测样品中分析物产生的荧光，该样品由多个激发光束激发，每个激发光束具有单独的光谱内容，包括多个光源，每个光源产生一个激发光束; 至少一个检测器，用于检测样品产生的发光; 以及光学组件，其为来自光源的每个激发光束定义不同的和固定的激发光路径到样品上的共同激发位点，并且限定用于从样品上的激发位点到激光位置处的发光光的共享发光光路 至少一个探测器，激发光路和发光路径位于样品的同一侧，光学组件包括样品侧光学器件，其将激发光投射到样品并收集来自样品的发光。

公开(公告)号：EP1307726B2

公开(公告)日：2014-06-25

申请号：EP01974113.1

申请日：2001-08-04

Applicant: Carl Zeiss Microscopy GmbH

Inventor： WOLLESCHENSKY, Ralf ,  MÖHLER, Gunter

IPC: G01J3/02 ,  B82Y20/00 ,  B82Y35/00 ,  G01J3/10 ,  G01J3/18 ,  G01J3/28 ,  G01J3/42 ,  G01Q60/22 ,  G01N21/64 ,  G02B21/00 ,  G02B21/16

CPC classification number: G01N21/64 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0213 ,  G01J3/10 ,  G01J3/1804 ,  G01J3/2803 ,  G01J3/42 ,  G01N21/6402 ,  G01N21/6428 ,  G01N21/6458 ,  G01Q60/22 ,  G02B21/0064 ,  G02B21/0076 ,  G02B21/008 ,  G02B21/16

公开(公告)号：EP2163870B1

公开(公告)日：2013-03-27

申请号：EP09166608.1

申请日：2009-07-28

Applicant: Thales

Inventor： Blanc, Jean-François ,  Garin, Stéphane

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/36 ,  H01L27/146 ,  H01L31/0232 ,  G02B23/00 ,  G02B5/28

CPC classification number: G02B23/00 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0213 ,  G01J3/0262 ,  G01J3/2823 ,  G01J3/36 ,  G02B5/285 ,  H01L27/14621

公开(公告)号：EP2318822A2

公开(公告)日：2011-05-11

申请号：EP09784735.4

申请日：2009-07-15

Applicant: Assaymetrics Limited

Inventor： GRAVES, Pierre, Robert

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/4406 ,  G01J2003/1243 ,  G01N2021/6421 ,  G01N2021/6467 ,  G01N2021/6491

Abstract: A photoluminescence spectrometer (100) is provided comprising; (i) a source of electromagnetic radiation (2) for exciting photoluminescence in a sample (16); (ii) a site (1) for location of the sample (iii) a detector (8) for detecting photoluminescence emitted from the sample and (iv) located in the optical path between the site for location of a sample and the detector, a means (10) of varying the intensity received by the detector of electromagnetic radiation having the same wavelength as the excitation radiation. The mean of varying the intensity may be formed by a tiltable interference filter or by a plurality of movable attenuating filters. A method of using such a spectrometer is also provided.

公开(公告)号：EP2163870A1

公开(公告)日：2010-03-17

申请号：EP09166608.1

申请日：2009-07-28

Applicant: Thales

Inventor： Blanc, Jean-François ,  Garin, Stéphane

IPC: G01J3/36 ,  H01L27/146 ,  H01L31/0232 ,  G02B23/00 ,  G02B5/28

CPC classification number: G02B23/00 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0213 ,  G01J3/0262 ,  G01J3/2823 ,  G01J3/36 ,  G02B5/285 ,  H01L27/14621

Abstract: Le filtre multispectral pour dispositif de détection d'images comporte une lame prismatique (85) comportant une première face interne (86) et une deuxième face externe (87), la première et la deuxième face (86, 87) étant inclinées l'une par rapport à l'autre d'un angle β et comporte au moins deux bandes spectrales différentes (91, 92, 93, 94) déposées indifféremment sur la première ou la deuxième face (86, 87) de la lame prismatique (85), les différentes bandes spectrales (91, 92, 93, 94) étant espacées l'une de l'autre d'une distance (D) prédéterminée.
Application aux imageurs multispectraux, en particulier aux imageurs Off Axis.
Ce filtre permet la suppression des images fantômes (ou échos parasites) générés au plan focal d'un imageur multispectral.

Abstract translation: 所述过滤器（88）具有在内部表面（86）和上外表面（87）设置有一个棱柱形板（85）。 的内，外表面是倾斜的相对于海誓山盟有棱镜角（测试版）。 不同光谱带均等地配置的内表面或外表面上。 的条带被间隔相对于彼此以预定的距离。 因此独立claimsoft包括用于多光谱成像器，包括一个图像检测装置。

公开(公告)号：EP1960748A2

公开(公告)日：2008-08-27

申请号：EP06851638.4

申请日：2006-08-21

Applicant: TUFTS UNIVERSITY ,  Bencic-Nagale, Sandra

Inventor： WALT, David R.

IPC: G01J1/32 ,  H01J40/14

CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/10 ,  G01J3/4406 ,  G01J2001/0276 ,  G01N21/6428 ,  G01N21/6458 ,  G01N2021/6441 ,  G01N2021/6484 ,  G01N2201/08 ,  G01N2201/088

Abstract: The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array b minimizing the effects of photobleaching. The imaging system has a light source (12), a variable exposure aperture (14), and a varia filter system (16). The system extends the longevity of sensors (28) by 1) using the variable exposure aperture to selectively expose sections of the sensor array containing representative numbers of each type of sensor, and/or 2) using the variable filter system to control the intensity of the excitation light, providing only the intensity required to induce the appropriate excitation and increasing intensity over time as necessary to counteract the effects of photobleaching.

公开(公告)号：EP1169624A4

公开(公告)日：2008-02-20

申请号：EP01905490

申请日：2001-02-15

Applicant: VARIAN AUSTRALIA

Inventor： WILSON PHILIP VALMONT ,  WILLIAMS MARK RICHARD ,  BRICKER DOWER CAMERON ,  HAMMER MICHAEL RON ,  MASTERS MARTIN KEITH ,  CAMPBELL STEWART RALPH ,  LAYTON PETER GEORGE

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G01J3/36 ,  G01J5/62 ,  G01N21/27 ,  G01N21/31

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/1809 ,  G01J3/2803 ,  G01J5/62 ,  G01J2003/1828 ,  G01N21/27 ,  G01N21/31

Abstract: A method and apparatus for the spectrochemical analysis of a sample in which a solid state array detector (82) is used to detect radiation (62) of spectrochemical interest. The invention involves the use of a shutter (72) adjacent the entrance aperture (70) of a polychromator (74-80) to expose the detector (82) to the radiation (62) for varying lengths of time whereby for short duration exposure times charge accumulation in elements (i.e. pixels) of the detector (82) due to high intensity components of the radiation is limited and for longer exposure times charge accumulation in elements (pixels) of the detector (82) due to feeble intesity components of radiation (62) is increased. This ensures that each reading of the detector (82) includes at least one exposure in which the amount of charge accumulated at each wavelength of interest is neither too little or too great. The problems of feeble radiation components not being accurately measurable and of high intensity radiation components exceeding the charge carrying capacity of elements (pixels) of the detector (82) are thereby able to be avoided. An attenuator (90) may be placed between the radiation source (60) and the detector (82) to permit longer exposure times to be used for very high intensity radiation.

公开(公告)号：EP1877756A1

公开(公告)日：2008-01-16

申请号：EP06728057.8

申请日：2006-04-26

Applicant: Koninklijke Philips Electronics N.V.

Inventor： UZUNBAJAKAVA, Natallia ,  KOLESNYCHENKO, Aleksey ,  VAN GOGH, Antonius ,  T HOOFT, Gert ,  SCHUURMANS, Frank

IPC: G01N21/27 ,  G01J3/42

CPC classification number: G01J3/32 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/28 ,  G01J2003/1282 ,  G01N21/274

Abstract: The invention relates to a multivariate calibration which can be used when the optical system used for that method does not comprise a multi-channel detector such as a CCD sensor or a line array of photodiodes. An optical system without a multi-channel detector doesn't allow to carry out preprocessing steps. Thus there is the need to carry out these preprocessing steps in another way. It is suggested to partially replace the preprocessing step by a measurement of the optical signal, whereby the measurement comprises transmitting or reflecting the optical signal by an optical element, thereby weighing the optical signal by a spectral weighing function. The advantage of the invention is to teach how such an optical system without a bulky and expensive CCD sensor can be used to carry out a multivariate calibration and preprocessing steps.

公开(公告)号：EP1659391A2

公开(公告)日：2006-05-24

申请号：EP05380243.5

申请日：2005-10-31

Applicant: Grifols, S.A.

Inventor： Pagés Pinyol, Josep

IPC: G01N21/03 ,  G01N21/27 ,  G01J3/28

CPC classification number: G01J3/02 ,  G01J3/0213 ,  G01J3/0218 ,  G01J3/12 ,  G01J3/2803 ,  G01N21/03 ,  G01N21/13 ,  G01N21/253 ,  G01N21/272 ,  G01N21/274 ,  G01N2201/0461 ,  G01N2201/082 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: The apparatus comprises a receiving body (1) for receiving the reaction containers (3) carrying the samples to be analyzed, with means (4,4',4'',5,5',5'',6,6') for causing each of the reaction containers to be passed through by a luminous signal of controlled wavelength, having means for conducting it to a scanning head where the luminous signals are picked up by a single CCD sensor (12), constituting a digital processing system for evaluating the absorbency of the corresponding sample.

Abstract translation: 所述装置包括：接收体（1），用于接收反应容器（3）承载所述样本以进行分析，有装置（4,4“ 4' ，5,5”，5' ”，6.6' ） 用于使每个反应容器要通过控制波长的发光信号通过的，具有用于将其导通的扫描头，其中发光信号由单个CCD传感器（12）拾取，构成数字处理系统，用于 评估样本对应的一种吸收性。

公开(公告)号：EP1090276B1

公开(公告)日：2006-05-10

申请号：EP99931922.1

申请日：1999-06-25

Applicant: Aspectrics, Inc.

Inventor： Hagler, Thomas

IPC: G01J3/12 ,  G01J3/32 ,  G01J3/433

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/0289 ,  G01J3/12 ,  G01J3/18 ,  G01J3/32 ,  G01J3/433 ,  G01J2001/4242 ,  G01J2003/2866

Abstract: A disc serving as a spatial radiation modulator has dispersed radiation filters thereon. Each filter has a transmittance or reflectance modulation function of the form sin (m theta + p pi /4), where m is a positive integer and p has one of the four values 0, 1, 2, 3. A radiation beam including selected wavelength components is diffracted into an elongated image dispersed according to wavelength. Different wavelength components are focused onto different filters on the modulator and are encoded by corresponding filters. Since the modulation functions of the filters are orthogonal to one another, it is possible to extract the amplitude of each wavelength component after it has been encoded or modulated by corresponding filter from the total detected signal during one measurement.