公开(公告)号：US20180059015A1

公开(公告)日：2018-03-01

申请号：US15690856

申请日：2017-08-30

Applicant: Sensii, Inc.

Inventor： Qiaochu Li ,  Wenting Xing

IPC: G01N21/3577 ,  G01N21/359 ,  G01N33/14 ,  G01N33/04 ,  G01N33/03

CPC classification number: G01N21/3577 ,  G01N21/359 ,  G01N33/03 ,  G01N33/04 ,  G01N33/146 ,  G01N2201/0221 ,  G01N2201/121 ,  G01N2201/129

Abstract: A personal liquid analysis system includes a portable liquid analyzer device, a mobile application as a user interface, and a cloud server for data analysis. The compact and portable liquid analyzer device is integrated by miniaturized near-infrared (NIR) optical sensors setup for spectroscopy measurement from a sample cell, control circuits, I/O user interface modules and wireless communication modules. The analyzer can be used to collect NIR spectra data from a liquid sample in the sample cell, and to transmit the data to a cloud server where compositional information is calculated, and presented to the user on the device and/or on a mobile application. The personal liquid analysis system enables the user to rapidly acquire qualitative and/or quantitative compositional information from liquid samples for a wide range of applications.

公开(公告)号：US09885698B2

公开(公告)日：2018-02-06

申请号：US15212549

申请日：2016-07-18

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01J3/14 ,  A61B5/145 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  G01J3/42 ,  G01J3/02 ,  H01S3/30 ,  G01J3/18 ,  G01M3/38 ,  G01J3/12 ,  G01N21/35 ,  G01N21/85 ,  G01N21/95 ,  H01S3/067 ,  H01S3/00

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes a measurement device having a light source with a plurality of light emitting diodes (LEDs) for measuring physiological parameters and configured to generate an optical beam with wavelengths including a near-infrared wavelength between 700 and 2500 nanometers. The measurement device includes lenses configured to deliver the optical beam to a sample of skin or tissue, which reflects the optical beam to a receiver located a first distance from one of the LEDs and a different distance from another of the LEDs, and is also configured to generate an output signal representing a non-invasive measurement on blood contained within the sample. The wearable device is configured to communicate with the smart phone or tablet, which receives, processes, stores and displays the output signal with the processed output signal configured to be transmitted over a wireless transmission link.

公开(公告)号：US20180031477A1

公开(公告)日：2018-02-01

申请号：US15221978

申请日：2016-07-28

Applicant: Eastman Kodak Company

Inventor： Allan Wexler ,  Steven C. Switalski ,  Grace Ann Bennett ,  Kimberly S. Lindner

IPC: G01N21/64 ,  G01N27/416

CPC classification number: G01N21/6428 ,  G01N21/643 ,  G01N21/6456 ,  G01N21/8851 ,  G01N27/4166 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2201/129 ,  Y10T436/145555

Abstract: A characteristic difference between first and second liquids is measured using a surface having a monolayer of a voltage sensitive chromophore that is covalently bound to the surface. The first liquid is brought into contact with the surface and it is irradiated with actinic radiation to measure a first fluorescence emission spectrum. The second liquid is also brought into contact with the surface and it is irradiated with actinic radiation to measure a second fluorescence emission spectrum. The first and second fluorescence emission spectra are compared to characterize a difference between the first and second fluids.

公开(公告)号：US20180024051A1

公开(公告)日：2018-01-25

申请号：US15658470

申请日：2017-07-25

Applicant: MKS Instruments, Inc.

Inventor： Peter Zemek ,  Robert M. Carangelo ,  Hongke Ye ,  Andrew Wright

IPC: G01N21/39 ,  G01N21/01 ,  G01N33/00 ,  G01N21/25

CPC classification number: G01N21/39 ,  G01N21/01 ,  G01N21/255 ,  G01N21/3504 ,  G01N33/0044 ,  G01N2021/0193 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/129

Abstract: Presented herein are systems and methods for quantifying trace and/or ultra-trace levels of a species—for example, H2S or H2O—in a natural gas line. The systems and methods employ a tunable laser, such as a tunable diode laser, vertical-cavity surface-emitting laser (VCSEL), external cavity diode laser or a vertical external-cavity surface-emitting laser (VECSEL) or a tunable quantum cascade laser (QCL). The laser produces an output beam over a set of one or more relatively narrow, high resolution wavelength bands at a scan rate from about 0.1 Hz to about 1000 Hz. A natural gas sample comprising a trace level of a species of interest passes through a flow cell into which the output beam from the laser is guided. An optical detector receives light from the flow cell, producing a signal indicative of the absorption attenuation from which the concentration of the trace species is determined.

公开(公告)号：US20180017540A1

公开(公告)日：2018-01-18

申请号：US15648028

申请日：2017-07-12

Applicant: Chevron U.S.A. Inc.

Inventor： Toni Zhang Miao ,  Rachel Mohler ,  Deyuan Kong ,  Ajit Ramachandra Pradhan ,  Michael E. Moir ,  Thomas Hoelen

IPC: G01N33/24 ,  G01N21/3563 ,  G01N21/552 ,  G01N30/02

CPC classification number: G01N33/241 ,  G01N21/3563 ,  G01N21/552 ,  G01N30/8693 ,  G01N2021/3595 ,  G01N2030/025 ,  G01N2030/8854 ,  G01N2201/0221 ,  G01N2201/129

Abstract: Disclosed is a method for generating a site specific model for predicting TPH concentration in soil. The method includes dividing a plurality of soil samples taken from a field site into two sets of samples. One set is analyzed using GC-FID, and the other set is analyzed using a handheld FTIR spectrometer with an ATR window to obtain FTIR-ATR absorbance data. Partial least squares regression analysis is used to correlate the GC-FID TPH concentration data with the absorbance data to generate a calibration model. The model is validated with soil samples having unknown TPH concentration. The model is used to predict the TPH concentration of soil samples taken from the field site analyzed using the handheld Fourier transform-infrared spectrometer to obtain FTIR-ATR absorbance data for the soil samples. During all absorbance measurements, each of the soil samples has a moisture content of 1 to 30 wt % and each sample is pressed against the ATR window with sufficient pressure to ensure intimate contact between the sample and the window.

公开(公告)号：US20170367583A1

公开(公告)日：2017-12-28

申请号：US15683277

申请日：2017-08-22

Applicant: Cedars-Sinai Medical Center

Inventor： Keith L. Black ,  Michael Baker ,  Howland Jones ,  Pramod Butte

IPC: A61B5/00 ,  G06K9/62 ,  A61B10/02 ,  G06T7/00 ,  G01N21/64 ,  A61B5/08

CPC classification number: A61B5/0071 ,  A61B5/00 ,  A61B5/0075 ,  A61B5/0091 ,  A61B5/08 ,  A61B5/4064 ,  A61B5/4255 ,  A61B5/441 ,  A61B5/7267 ,  A61B10/02 ,  A61B2576/026 ,  G01N21/6402 ,  G01N21/6408 ,  G01N2201/06113 ,  G01N2201/129 ,  G06K9/6267 ,  G06T7/0012 ,  G06T2207/10064 ,  G06T2207/30016 ,  G06T2207/30028 ,  G06T2207/30061 ,  G06T2207/30068 ,  G06T2207/30088

Abstract: Described herein are methods and systems for analyzing a sample by applying time resolved laser induced fluorescence spectroscopy to the sample to measure lifetime time decay profile data relating to the sample, and applying multivariate analysis to process the data so as to classify a sample as, for example, normal or abnormal. The sample may be cells, fluid or tissue from any organ. The sample may be in vitro or in vivo. The data may be obtained in situ or in vitro.

公开(公告)号：US20170328826A1

公开(公告)日：2017-11-16

申请号：US15593959

申请日：2017-05-12

Applicant: BD Biosciences

Inventor： Eric Diebold ,  Keegan Owsley ,  Jonathan Lin ,  Matthew Bahr

IPC: G01N15/14 ,  G06T7/00 ,  G06T7/246 ,  G01N21/64 ,  G01N15/00 ,  G01N15/10

CPC classification number: G01N15/1475 ,  G01N15/1429 ,  G01N15/147 ,  G01N21/6456 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/144 ,  G01N2201/06113 ,  G01N2201/10 ,  G01N2201/12 ,  G01N2201/129 ,  G06T7/0012 ,  G06T7/246 ,  G06T7/521 ,  G06T2207/30024

Abstract: In one aspect, a system for performing flow cytometry is disclosed, which comprises a laser for generating laser radiation for illuminating a sample, at least one detector for detecting at least a portion of a radiation emanating from the sample in response to said illumination so as to generate a temporal signal corresponding to said detected radiation, and an analysis module for receiving said temporal signal and performing a statistical analysis of said signal based on a forward model to reconstruct an image of said sample.

公开(公告)号：US20170254741A1

公开(公告)日：2017-09-07

申请号：US15599765

申请日：2017-05-19

Applicant: Sumitomo Electric Industries, Ltd. ,  Cyfuse Biomedical K.K. ,  Kyoto Stem Cell Innovation, Inc.

Inventor： Hiroshi Suganuma ,  Takuya Okuno ,  Asako Motomura ,  Shizuka Akieda ,  Manami Tsuji ,  Yuna Okina ,  Yoko Sugiyama ,  Kazuhiro Aiba ,  Li Liu

IPC: G01N21/25 ,  G06F17/30 ,  G01N21/359 ,  G06N99/00 ,  G01N17/00 ,  G01N21/01

CPC classification number: G01N21/255 ,  G01N17/004 ,  G01N21/01 ,  G01N21/359 ,  G01N21/4738 ,  G01N2021/0106 ,  G01N2201/10 ,  G01N2201/129 ,  G06F16/583 ,  G06K9/00147 ,  G06K9/0055 ,  G06N20/00 ,  G06T2207/30024

Abstract: A quality evaluation method includes an acquisition step of acquiring spectral data related to transmitted light or diffusely reflected light from a cell mass by irradiating the cell mass with measurement light including near-infrared light, and an evaluation step of evaluating quality of the cell mass, based on the spectral data of the cell mass acquired in the acquisition step.

公开(公告)号：US20170199139A1

公开(公告)日：2017-07-13

申请号：US14992319

申请日：2016-01-11

Applicant: International Business Machines Corporation ,  GlobalFoundries, Inc.

Inventor： Lisa F. Edge ,  Gangadhara R. Muthinti ,  Shariq Siddiqui

IPC: G01N27/02 ,  G01N21/25

CPC classification number: G01N27/02 ,  G01B11/0625 ,  G01B11/0683 ,  G01N21/211 ,  G01N21/25 ,  G01N21/27 ,  G01N21/8422 ,  G01N21/9501 ,  G01N2021/3568 ,  G01N2021/4126 ,  G01N2201/129

Abstract: In an embodiment, a method comprises fitting a spectroscopic data of a layer in a layered structure to a dielectric function having a real part and an imaginary part; confirming that the dielectric function is physically possible; based on the dielectric function not being physically possible, repeating the fitting the spectroscopic data, or, based on the dielectric function being physically possible, defining an n degree polynomial to the dielectric function; determining a second derivative and a third derivative of the n degree polynomial; equating the second derivative to a first governing equation and the third derivative to a second governing equation and determining a constant of the first governing equation and the second governing equation; and based on the key governing equations, determining one or more of a band gap, a thickness, and a concentration of the layer.

公开(公告)号：US20170156646A1

公开(公告)日：2017-06-08

申请号：US15239309

申请日：2016-08-17

Applicant: Zyomed Corp.

Inventor： Sandeep Gulati ,  Timothy L. Ruchti ,  William Van Antwerp ,  John L. Smith

IPC: A61B5/145 ,  A61B5/1455 ,  G01N33/49 ,  G01N21/49 ,  G01N21/359 ,  G01N33/483

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/024 ,  A61B5/02416 ,  A61B5/02433 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2560/0223 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N33/4833 ,  G01N33/49 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/067 ,  G01N2201/12 ,  G01N2201/129

Abstract: In a noninvasive system for detection/measurement of glucose and other analytes in a medium such as tissue, spectra from the medium are deconstructed into features. Conditioned features, which contain frequency components specific to glucose or the other analytes, are derived from one or more features by modulating a carrier kernel with the feature. The conditioned features are computationally collided with one or more Zyotons that are co-dependent with the conditioned features. One or more collisions amplify a property of the analyte e.g., energy absorbed by glucose in tissue from radiation directed to the skin. A gradient of several values of the amplified property, each value corresponding to a particular radiation pattern according to a spectroscopic tomographic sequence, is used to select a suitable projector curve, with which a representative amplified value is projected to an accurate estimate of the concentration of glucose or the other analytes, without needing personalized calibration.