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    Multivariate detection of molecules in bioassay
    281.
    发明公开
    Multivariate detection of molecules in bioassay 审中-公开
    Multivariater Nachweis vonMolekülenin Bioassay

    公开(公告)号：EP1925929A1

    公开(公告)日：2008-05-28

    申请号：EP06124812.6

    申请日：2006-11-27

    Applicant: Koninklijke Philips Electronics N.V.

    Inventor： The designation of the inventor has not yet been filed

    IPC: G01N21/25 ,  G01J3/32 ,  G01J3/36

    CPC classification number: G01J3/02 ,  G01J3/0229 ,  G01J3/0294 ,  G01J3/32 ,  G01J3/36 ,  G01N21/6428 ,  G01N2021/6441

    Abstract: The invention relates to detection of target molecules in an assay, such as a bio-assay, and in particular to multivariate detection of target molecules. A detector system is disclosed, the detection system comprising an optical guide element (16) for directing luminescence radiation (7) from an associated sample towards a multivariate element (8), the sample contains probe molecules that specifically binds to target molecules; a multivariate element (8) for spatially separating the luminescence radiation (7; 14; 15) to create a plurality of spectral patterns; and a detector (13) for detecting the intensity of a set of spectral patterns, so as to determine the presence of binding complexes between probe molecules and target molecules in the sample.

    Abstract translation: 本发明涉及在分析中的靶分子的检测，例如生物测定，特别涉及目标分子的多变量检测。 公开了一种检测器系统，所述检测系统包括用于将相关样品的发光辐射（7）引向多变量元件（8）的光导元件（16），所述样品含有特异性结合靶分子的探针分子; 用于空间分离发光辐射（7; 14; 15）以产生多个光谱图案的多元素（8）; 以及用于检测一组光谱图的强度的检测器（13），以便确定样品中探针分子和靶分子之间的结合复合物的存在。

    LIGHT MEASURING INSTRUMENT
    284.
    发明公开
    LIGHT MEASURING INSTRUMENT 审中-公开
    LICHTMESSGERÄT

    公开(公告)号：EP1906172A1

    公开(公告)日：2008-04-02

    申请号：EP06768161.9

    申请日：2006-07-12

    Applicant: Olympus Corporation

    Inventor： YAMAGUCHI, Mitsushiro c/o OLYMPUS INT. PROP. SERV.CO., LTD. ,  HARADA, Mitsuo c/o OLYMPUS INTEL. PROP. SERV. CO., LTD.

    IPC: G01N21/64

    CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/0289 ,  G01J3/06 ,  G01J3/08 ,  G01J3/10 ,  G01J3/42 ,  G01J2003/123 ,  G01N21/6428 ,  G01N21/6445

    Abstract: An optical measurement apparatus which includes at least one each of a light source (1), an optical element, a photodetector (2), and a sample container (22), and which measures a physical property of a biological sample in a solution retained by the sample container according to a plurality of kinds of measurement items, wherein a combination of the light source, the optical element, and the photodetector is selected or changed according to the measurement item, and a position where the photodetector is located is adjusted according to the selection or change based on intensity of light accepted by the photodetector.

    Abstract translation: 一种光学测量装置，其包括光源（1），光学元件，光电检测器（2）和样品容器（22）中的至少一个，并且测量保留的溶液中的生物样品的物理性质 通过根据测量项目选择或改变光源，光学元件和光电检测器的组合的多种测量项目的样本容器，并且根据测量项目调整光电探测器所在的位置 基于由光电检测器接收的光的强度进行选择或改变。

    OPTICAL SENSOR DEVICE AND METHOD FOR SPECTRAL ANALYSIS
    287.
    发明授权
    OPTICAL SENSOR DEVICE AND METHOD FOR SPECTRAL ANALYSIS 有权
    OPTISCHE SENSOREINRICHTUNG UND VERFAHREN ZUR SPEKTRALANALSE

    公开(公告)号：EP1344193B1

    公开(公告)日：2007-07-04

    申请号：EP01271610.6

    申请日：2001-12-18

    Applicant: De La Rue International Limited

    Inventor： KLOCK, Hansjörg ,  JONES, Robert ,  HAZEL, Michael, Stuart

    IPC: G07D7/12 ,  G01J3/28 ,  G01J3/18 ,  G01J3/04

    CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0294 ,  G01J3/04 ,  G01J3/18 ,  G01J3/2803 ,  G07D7/1205

    Abstract: An optical detection device for validating bank rates has several input apertures, an imaging device (12), a diffraction grating (15.1, 15.2, 15.3) associated with each input aperture (11.1, 11.2, 11.3) and a detection array (17). The diffraction grating (15.1, 15.2, 15.3) is rotated at angle of e.g.45 degrees relative to the orientation of the linear detection array (17). This arrangement enables the spectra of multiple points to be measured simultaneously. The angle of rotation, the pitch of the apertures (11.1, 11.2, 11.3) and a pitch of the diffraction grating (15.1, 15.2, 15,3) are selected in such a way that the spectra of sad multiple points are contiguously mapped onto the detection array (17) has a single linear array of color sensitive detection pixels. The acxis of the linear array is offset with respect to an optical axis (7) of the optical detection device.

    Abstract translation: 用于验证纸币的光学检测装置具有若干输入孔，一个想象装置（12），与每个输入孔（11.1,11.2,11.3）相关联的衍射光栅（15.1,15.2,15.3）和一个检测阵列（17）。 衍射光栅（15.1,15.2,15.3）以例如角度旋转。 相对于线性检测阵列（17）的取向为45度。 这种布置使得能够同时测量多个点的光谱。 选择旋转角度，孔径（11.1,11.2,11.3）的间距和衍射光栅（15.1,15.2,15.3）的间距，使得所述多个点的光谱被连续地映射到检测器 阵列（17）具有彩色敏感检测像素的单个线性阵列。 线性阵列的轴相对于光学检测装置的光轴（7）偏移。

    MEASURING ANALYTES FROM AN ELECTROMAGNETIC SPECTRUM USING A WAVELENGTH ROUTER
    289.
    发明公开
    MEASURING ANALYTES FROM AN ELECTROMAGNETIC SPECTRUM USING A WAVELENGTH ROUTER 审中-公开
    分析从具有波长路由器电磁频谱测量

    公开(公告)号：EP1662986A2

    公开(公告)日：2006-06-07

    申请号：EP04781974.3

    申请日：2004-08-23

    Applicant: C8

    Inventor： LIPSON, Jan

    IPC: A61B5/00

    CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/1838 ,  G01N21/274 ,  G01N21/31 ,  G03H1/0005

    Abstract: Weak signals scattered from analytes at multiple wavelengths can be summed to illuminate either a single detector or a multiplicity of detectors, offering the possibility of concentrating the spectral energy on a smaller total detector area. In addition, a method is disclosed whereby a calibration of the resulting signal for a given analyte can be obtained by means of measuring the quantity of water in the sample volume and by means of measuring the salinity of the fluid in the sample volume.

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