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    Method and spectroscopic analysis appliance, especially for analysing food, with multi-channel treatment of spectral data
    282.
    发明授权
    Method and spectroscopic analysis appliance, especially for analysing food, with multi-channel treatment of spectral data 有权
    方法和光谱分析仪器，特别是用于分析食物，多通道处理光谱数据

    公开(公告)号：US08987686B2

    公开(公告)日：2015-03-24

    申请号：US13516358

    申请日：2010-12-08

    Applicant: Jad Rizkallah ,  Inès Birlouez-Aragon

    Inventor： Jad Rizkallah ,  Inès Birlouez-Aragon

    IPC: G01N21/64 ,  G01N33/02

    CPC classification number: G01N21/64 ,  G01N33/02 ,  G01N2021/6419 ,  G01N2201/129

    Abstract: A method for the spectroscopic analysis of a sample is provided. The method including the illumination of the sample to be analyzed by a plurality of luminous excitation rays with respective wavelengths; the acquisition and the pre-treatment of frontal fluorescence spectra, each spectrum corresponding to a respective luminous excitation ray; for each sample, the calculation of a score vector by applying a multi-channel statistical model to the pre-treated spectra; and the determination of at least one parameter selected from a quality indicator of the sample and a parameter characterizing a method that has been applied to the sample, from said score vector. The average spectral distance between the luminous excitation rays is at least 50 nm, over a spectral range of at least 100 nm. The invention also relates to an appliance for implementing such a method.

    Abstract translation: 提供了一种用于样品的光谱分析的方法。 该方法包括通过具有各种波长的多个发光激发光照射要分析的样品; 前额叶荧光光谱的获取和预处理，每个光谱对应于相应的发光激发光线; 对于每个样本，通过将多通道统计模型应用于预处理的光谱来计算得分矢量; 以及从所述得分向量确定从样本的质量指标中选择的至少一个参数和表征已经应用于样本的方法的参数。 在至少100nm的光谱范围内，发光激发光线之间的平均光谱距离至少为50nm。 本发明还涉及一种用于实现这种方法的设备。

    METHOD FOR SENSOR CALIBRATION
    283.
    发明申请
    METHOD FOR SENSOR CALIBRATION 审中-公开
    传感器校准方法

    公开(公告)号：US20140350868A1

    公开(公告)日：2014-11-27

    申请号：US14359606

    申请日：2012-11-13

    Applicant: EPISENTEC AB

    Inventor： Anders Hanning

    IPC: G01N21/59

    CPC classification number: G01N21/59 ,  G01N21/274 ,  G01N21/553 ,  G01N2021/5903 ,  G01N2201/129

    Abstract: The present invention provides a method of determining the amount of an optical probe species binding to or releasing from an optical sensor surface characterized in that the determination comprises the steps of: a) determining, at one single wavelength or at more than one wavelength, a physical measurand (xi) that is related to the absorptivity of said probe, b) correlating the value of the measurand to the amount of said optical probe species binding to or releasing from said surface, respectively, wherein the physical measurand (xi) of step a) is a physical measurand in which the contribution from the refractive index is substantially zero. The present invention further provides different uses of a peak width as well as a computer program product and reagent kits for the disclosed methods.

    Abstract translation: 本发明提供一种确定与光学传感器表面结合或从光学传感器表面释放的光学探针物质的量的方法，其特征在于，所述测定包括以下步骤：a）在单个波长或多于一个波长处确定 与所述探针的吸收性相关的物理测量（xi），b）分别将所述被测量的值与所述光学探针物质与所述表面结合或释放的量相关联，其中所述步骤的物理测量（xi） a）是物理测量，其中折射率的贡献基本为零。 本发明进一步提供峰宽度的不同用途以及用于所公开方法的计算机程序产品和试剂盒。

    CALIBRATION CURVE CREATION METHOD, CALIBRATION CURVE CREATION APPARATUS, AND TARGET COMPONENT GAUGING APPARATUS
    284.
    发明申请
    CALIBRATION CURVE CREATION METHOD, CALIBRATION CURVE CREATION APPARATUS, AND TARGET COMPONENT GAUGING APPARATUS 审中-公开
    校准曲线创建方法，校准曲线创建装置和目标组件测量装置

    公开(公告)号：US20140297197A1

    公开(公告)日：2014-10-02

    申请号：US14224872

    申请日：2014-03-25

    Applicant: Seiko Epson Corporation

    Inventor： Hikaru KURASAWA ,  Yoshifumi ARAI

    IPC: G01N33/00

    CPC classification number: G01N33/0098 ,  G01N21/27 ,  G01N2201/129

    Abstract: A calibration curve creation method is capable of performing accurate measurement from a piece of observation data. The calibration curve creation method includes (a) acquiring observation data regarding a plurality of samples of a subject, (b) acquiring the content of a target component in each sample, (c) estimating a plurality of independent components at the time of separation into a plurality of independent components of each sample and calculating a mixing coefficient corresponding to the target component for each sample, and (d) calculating the regression equation of the calibration curve. The process (c) includes a step of calculating an independent component matrix by executing first pre-processing including correcting the observation data, second pre-processing including whitening, and independent component analysis processing in this order. A process suitable for the observation data is selected from a plurality of processes, and is used as the first pre-processing and the second pre-processing.

    Abstract translation: 校准曲线创建方法能够从一条观察数据执行准确的测量。 校准曲线生成方法包括：（a）获取关于被检体的多个样本的观察数据，（b）获取各样本中的目标成分的含量，（c）在分离时估计多个独立成分 每个样本的多个独立分量，并计算与每个样本的目标分量对应的混合系数，以及（d）计算校准曲线的回归方程。 方法（c）包括通过执行包括校正观察数据的第一预处理，包括白化的第二预处理和独立分量分析处理来依次计算独立分量矩阵的步骤。 从多个处理中选择适合于观察数据的处理，并且将其用作第一预处理和第二预处理。

    System for noninvasive determination of analytes in tissue
    285.
    发明授权
    System for noninvasive determination of analytes in tissue 有权
    非侵入性测定组织中分析物的系统

    公开(公告)号：US08730047B2

    公开(公告)日：2014-05-20

    申请号：US13444989

    申请日：2012-04-12

    Applicant: Trent Ridder ,  Ben Ver Steeg ,  Oscar Lazaro

    Inventor： Trent Ridder ,  Ben Ver Steeg ,  Oscar Lazaro

    IPC: G08B13/14 ,  A61B5/1455

    CPC classification number: A61B5/0075 ,  A61B5/0088 ,  A61B5/117 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0264 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/14 ,  G01J2003/1286 ,  G01N21/274 ,  G01N21/359 ,  G01N21/474 ,  G01N2201/129

    Abstract: An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments.

    Abstract translation: 一种用于通过定量红外光谱法非临床确定人体组织的分析物质的临床相关水平的精确度和准确度的装置和方法。 该系统包括优化的子系统，以应对组织光谱的复杂性，高信噪比和光度精度要求，组织采样误差，校准维护问题和校准转移问题。 子系统可以包括照明/调制子系统，组织采样子系统，数据采集子系统，计算子系统和校准子系统。 本发明可以提供来自相同光谱信息的分析物质性质确定和鉴别确定或验证，使得未经授权的使用或误导结果比使用单独的分析物和身份确定的系统更不可能。 本发明可用于控制和监视访问受控环境的个人。

    SEED SORTER
    287.
    发明申请
    SEED SORTER 有权

    公开(公告)号：US20140061104A1

    公开(公告)日：2014-03-06

    申请号：US14041395

    申请日：2013-09-30

    Applicant: Monsanto Technology LLC

    Inventor： Kevin L. Deppermann ,  James Crain ,  Sam R. Eathington ,  Mike Graham ,  Steven H. Modiano

    IPC: B07C5/00

    CPC classification number: G06K9/00 ,  B07C5/00 ,  B07C5/10 ,  B07C5/34 ,  B07C5/3422 ,  B07C5/3425 ,  G01J3/0218 ,  G01J3/10 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/85 ,  G01N2021/0339 ,  G01N2021/8592 ,  G01N2201/0627 ,  G01N2201/129

    Abstract: A seed sorter system is operable to sort seeds based on one or more characteristics of the seeds. The system includes a seed loading station operable to isolate individual seeds from a plurality of seeds and load the isolated seeds into a seed tray, an imaging and analysis subsystem operable to collect image data of at least a top portion and a bottom portion of each of the seeds in the seed tray and determine one or more characteristics of each of the seeds, a seed off-load and sort station operable to remove the seeds from the seed tray and sort the seeds to desired receptacles based on the determined one or more characteristics of the seeds, and a seed transport operable to move the seed tray between the seed loading station, the imaging and analysis subsystem, and the seed off-load and sort station.

    Abstract translation: 种子分拣机系统可操作以基于种子的一个或多个特征对种子进行分类。 该系统包括种子加载站，其可操作以从多个种子中分离单个种子并将分离的种子装载到种子托盘中，成像和分析子系统可操作以收集每个种子的至少顶部和底部的图像数据 种子在种子托盘中并确定每个种子的一个或多个特征，种子卸载和分选站可操作以从种子托盘移除种子并基于所确定的一个或多个特征将种子分类到所需的容器 的种子，以及可操作以在种子加载站，成像和分析子系统以及种子卸载和分类站之间移动种子盘的种子传送。

    METHOD, APPARATUS, AND SYSTEM FOR EXAMINING OPTICALLY A SAMPLE CARRIED IN A PLURALITY OF WELLS
    288.
    发明申请
    METHOD, APPARATUS, AND SYSTEM FOR EXAMINING OPTICALLY A SAMPLE CARRIED IN A PLURALITY OF WELLS 有权
    用于检查在多个细胞中携带的光学样品的方法，装置和系统

    公开(公告)号：US20130277545A1

    公开(公告)日：2013-10-24

    申请号：US13877266

    申请日：2011-09-30

    Applicant: Niklas Törnkvist ,  Pekka Hänninen

    Inventor： Niklas Törnkvist ,  Pekka Hänninen

    IPC: G01V8/20

    CPC classification number: G01V8/20 ,  G01N21/6408 ,  G01N21/6452 ,  G01N21/6454 ,  G01N2201/0626 ,  G01N2201/129

    Abstract: An apparatus and method are disclosed for examining optically a sample carried in a plurality of wells. A holder is adapted to receive and hold in place a sample carrier. A plurality of excitation means selectively introduce excitation towards a spatially limited portion of a sample carrier held in place by said holder. Detecting means receive and detect emission radiation coupled out from a light output window of a sample carrier held in place by said holder. Said detecting means is common to said excitation means and is configured to receive emission radiation from a plurality of different spatially limited portions of a sample carrier held in place by said holder.

    Abstract translation: 公开了用于光学检查在多个井中携带的样品的装置和方法。 支架适于接收和保持样品载体。 多个激励装置选择性地将激励朝向由所述保持器保持就位的样品载体的空间限制部分引入。 检测装置接收和检测由所述保持器保持在适当位置的样品载体的光输出窗口耦合出的发射辐射。 所述检测装置对于所述激励装置是共同的，并且被配置成从由所述保持器保持在适当位置的样本载体的多个不同的空间限制部分接收发射辐射。

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