Abstract:
마이크로니들 어레이 및 이를 구비하는 피부침투장치에 대한 발명이 개시된다. 개시된 발명은: 기판부와; 기판부에 돌출되게 형성되고, 피부에 침투되어 유체를 피부에 침투시키는 복수 개의 마이크로니들을 포함하는 니들부; 및 마이크로니들의 단부에 형성되어 피부에 침투되는 마이크로니들을 통한 유체의 피부 침투를 유도하는 침투유도부를 포함한다. 본 발명에 따르면, 마이크로니들 어레이를 피부에 접촉시키는 것 만으로도 피부각질층에 미세구멍을 형성하는 작용과, 헤드부의 유체분출부를 통해 유체가 피부에 도포되는 작용이 동시에 이루어지도록 하므로, 유용성분의 전달 효과가 우수하면서도 사용이 편리한 장점이 있다.
Abstract:
PURPOSE: A cosmetic composition containing an Ilex paraguayensis fermentation extract is provided to improve anti-wrinkling, anti-aging, and skin elasticity. CONSTITUTION: An Ilex paraguayensis fermentation extract is prepared by inoculating Ilex paraguayensis with Pseudogulbenkiania spp.(deposit number KCCM11205P) and fermenting. A cosmetic composition for improving anti-wrinkling contains 0.01-20 wt% of the extract. The cosmetic composition is manufactured in the form of a solution, a suspension, an emulsion, a paste, a gel, a cream, a lotion, a powder, a pack, a soap, a surfactant-containing cleansing, an oil, and a spray. [Reference numerals] (AA) Cytotoxicity; (BB) Mate extract 5%; (CC) Mate extract 10%; (DD) Mate fermented extract 5%; (EE) Mate fermented extract 10%
Abstract:
PURPOSE: A method for preparing 5,6-dihydroxy indole using Kitasatospora sp. DG09 is provided to remarkably enhance melanogenesis and tyrosinase production. CONSTITUTION: A method for preparing 5,6-dihydroxy indole comprises: a step of culturing a transformant containing Kitasatospora sp. DG09(deposit number KCCM11178P) or tyrosinase nucleic acid sequence of sequence number 3; and a step of collecting 5,6-dihydroxy indole from the culture liquid. A tyrosinase has an amino acid sequence of sequence number 2 prepared from Kitasatospora sp. DG09. The tyrosinase has a nucleic acid sequence of sequence number 3.
Abstract:
PURPOSE: A composition containing Lindera obtusiloba extract and Euonymus alatus extract is provided to ensure stability at room temperature for a long time and to prevent and treat atopic dermatitis. CONSTITUTION: A composition for preventing and treating atopic dermatitis contains Lindera obtusiloba extract and Euonymus alatus extract as active ingredient. The extract is 1,2-pentanediol aqueous solution containing 30-70 (v/v)% of water. The composition is a cosmetic composition. The Lindera obtusiloba extract and Euonymus alatus extract are contained in 1:1 weight ratio. The cosmetic composition is used in the form of skin, lotion, massage cream, or foaming formulation.