Abstract:
본발명은재조합인플루엔자 A 바이러스, 이의제조방법및 이를포함하는 clade 2.3.4.4B에속하는 H5 혈청형인플루엔자 A 바이러스에대한백신조성물을제공한다. 본발명은고병원성조류인플루엔자바이러스에방어효과를나타내는유전자재조합백신을제조함으로써, 해외로부터유입되거나국내에서발생하는 H5 혈청형고병원성조류인플루엔자발생에대비한방어효과를통해질병방제에기여할수 있다. 또한, 상기백신조성물은 HA 분절부위의고병원성유전자가제거되어병원성이약하고안전성이우수할뿐만아니라, 종란(egg) 내증식성및 닭에서의방어능이우수하다.
Abstract:
PURPOSE: A recombinant Baculovirus containing p12 gene of African swine fever(ASF) virus and a method for diagnosing the antibody of African swine fever(ASF) virus are provided, thereby rapidly and safely testing a large amount of serum samples. CONSTITUTION: The recombinant Baculovirus ASFV p12/BacPAK6 (KFCC-11149) contains p12 gene of African swine fever(ASF) virus represented by SEQ ID NO: 1 and produce p12 proteins, in which the p12 gene of African swine fever(ASF) virus is a conserved gene among all kinds of African swine fever(ASF) virus, and has not virulence activity. The diagnosis of the antibody of African swine fever(ASF) virus uses the p12 proteins produced from recombinant Baculovirus ASFV p12/BacPAK6 (KFCC-11149) as an antigen.
Abstract:
PURPOSE: A process for producing a polyester having high molecular weight and excellent biodegradability using a composite catalyst is provided which improves reaction velocity and promotes productivity. CONSTITUTION: A process comprises the esterification and polycondensation of carboxylic acids comprising aliphatic dicarboxylic acid containing 2 to 14 carbon atoms or its derivatives, aromatic or aliphatic carboxylic acid or its derivatives with glycols in the presence of a composite catalyst comprising a titanium compound, a zinc compound, antimony compound, and phosphorous compound. The polyester prepared by the process is excellent in biodegradability and thermal and mechanical properties.