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公开(公告)号：KR102244492B1
公开(公告)日：2021-04-26
申请号：KR1020200136518
申请日：2020-10-21
Applicant: 대한민국(관리부서:국립수산과학원) , 주식회사 엘지생활건강
IPC: C12N1/20 , A01N63/20 , A23K10/16 , A23K20/00 , A61K35/74 , A61P1/02 , A61K8/99 , A61Q19/00 , C12R1/225
Abstract: 본발명은어병세균및 치아우식균을비롯한여러병원성세균에대해항균활성이높고멜라닌의생성을억제하며콜라겐의합성을촉진하여다양한식·의약용소재로활용가능한신규락토바실러스속(Lactobacillus sp.) 균주및 그의용도를제공한다.
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公开(公告)号：KR101985663B1
公开(公告)日：2019-06-05
申请号：KR1020170121556
申请日：2017-09-21
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: C07K7/06 , A23K20/147 , A23K20/195
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公开(公告)号：KR20180035025A
公开(公告)日：2018-04-05
申请号：KR20160124978
申请日：2016-09-28
Applicant: 대한민국(관리부서:국립수산과학원)
Abstract: 본발명은피부에대한자극을최소화하고우수한미백활성을나타내는퀴놀론계화합물을유효성분으로함유하는미백용화장료조성물을제공한다.
Abstract translation: 本发明提供含有喹诺酮化合物作为有效成分的美白化妆品组合物，该化合物对皮肤的刺激性最小并且表现出优异的增白活性。
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公开(公告)号：KR101749548B1
公开(公告)日：2017-06-21
申请号：KR1020150145265
申请日：2015-10-19
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: C07K7/08 , C07K14/435 , A23L3/3526 , A61K8/64 , A61K38/08
Abstract: 본발명은항균특성및 새로운생리학적활성으로서항암특성을가지는펩타이드, 이펩타이드를코딩하는핵산및 이펩타이드또는핵산의응용에관한것이다. 본발명에따라합성된펩타이드, 또는이 펩타이드를코딩하는핵산이삽입된벡터를유효성분으로사용하여, 항균및/또는항암조성물, 예를들어약학적조성물, 화장품조성물및/또는식품첨가제로활용될수 있다.
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公开(公告)号：KR101725326B1
公开(公告)日：2017-04-12
申请号：KR1020150056985
申请日：2015-04-23
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: C12N1/20 , C12P17/12 , B01D15/08 , C07D215/233
CPC classification number: B01D15/08 , C07D215/233 , C12N1/20 , C12P17/12
Abstract: 본발명은붉은멍게내장시료로부터분리된항균활성물질생산능이우수한미생물인신규슈도알테르모나스속 M2 균주, 상기균주로부터생산되는항균활성물질을제공한다.
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Patent Agency Ranking
公开(公告)号：KR101642779B1
公开(公告)日：2016-07-28
申请号：KR1020150041376
申请日：2015-03-25
Applicant: 대한민국(관리부서:국립수산과학원)
CPC classification number: C07K19/00 , C12N15/62 , C12N15/63 , C07K2319/20 , C12N15/635
Abstract: 본발명은짧은막관통단백질의 C-말단에복수의분자내이황화결합을갖는단백질이연결된융합단백질을암호화하는폴리뉴클레오티드가프로모터에작동가능하게연결된, 재조합발현벡터를제공한다.
Abstract translation: 本发明涉及多硫键多肽的重组表达系统发育。 此外，本发明提供了重组表达载体，其中多核苷酸可操作地连接至启动子，其中所述多核苷酸编码与短跨膜蛋白C末端具有多个分子内二硫键的蛋白质连接的融合蛋白。
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公开(公告)号：KR101499689B1
公开(公告)日：2015-03-09
申请号：KR1020140124525
申请日：2014-09-18
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: C12Q1/68
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: 본 발명은 넙치 암수 유전체를 비교 분석하여 넙치 종묘의 암수를 유전적으로 판별할 수 있는 단일염기다형성(SNP) 마커를 제공한다.
Abstract translation: 本发明的目的是在性别歧视之前提供用于区分橄榄比目鱼的性别的标记。 该方法中提供的是单核苷酸多态性（SNP）标记，通过比较和分析男性和女性橄榄苜蓿的基因组，可以一般地区分橄榄比目鱼的性别。 提供了一种DNA多核苷酸或补偿其的多核苷酸，用于区分选自包含各种多核苷酸的组的橄榄比目鱼的性别。
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公开(公告)号：KR101184011B1
公开(公告)日：2012-09-27
申请号：KR1020100043855
申请日：2010-05-11
Applicant: 대한민국(관리부서:국립수산과학원)
CPC classification number: C12N15/625 , C07K2319/02 , C07K2319/50 , C12N15/70 , C12P21/06
Abstract: The present invention relates to expression vectors and methods for enhancing soluble expression and secretion of a heterologous protein, particularly a bulky folded active heterologous protein which has one or more transmembrane-like domains or intramolecular disulfide bonds by linking a leader peptide with acidic or basic pI and high hydrophilicity thereto; by substituting one or more amino acids within N-terminal of the heterologous protein with ones having acidic or neutral pI and high hydrophilicity; or reducing elevating GRNA value of a polynucleotide encoding the leader peptide having basic pI value and high hydrophilicity. The expression vector and the method may be used to produce of heterologous protein and to transduce of therapeutic proteins in a patient by preventing formation of insoluble inclusion body and by enhancing secretional efficiency of the heterologous protein into the periplasm or outside cell.
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公开(公告)号：KR101121077B1
公开(公告)日：2012-06-27
申请号：KR1020090076221
申请日：2009-08-18
Applicant: 대한민국(관리부서:국립수산과학원)
Abstract: PURPOSE: A novel gene encoding Paralichthys olivaceus-derived antibacterial peptide, bea-defensin is provided to ensure pivotal immune response function and to be used in developing natural antibiotics. CONSTITUTION: A Paralichthys olivaceus-derived antibacterial polypeptide comprises: a polypeptide encoded by cDNA having one of nucleic acid sequence among sequence numbers 1-5; a polypeptide encoded by gDNA having one of nucleic acid among sequence numbers 6-10; or a polypeptide having one of amino acid sequence among sequence numbers 11-15. The antibacterial polypeptide is anionic. Antibiotics or feed additives contain the antibacterial polypeptide, mutant thereof, or active fragment thereof as an active ingredient.
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公开(公告)号：KR1020100138208A
公开(公告)日：2010-12-31
申请号：KR1020090056632
申请日：2009-06-24
Applicant: 대한민국(관리부서:국립수산과학원)
CPC classification number: C12Q1/6844 , C12N15/11 , C12Q1/686
Abstract: PURPOSE: A DNA marker for determining Anguilla japonica species and a method for determining Anguilla japonica using the same are provided to distinguish domestic Anguilla and foreign Anguilla. CONSTITUTION: A genome DNA-derived polynucleotide for determining Anguilla japonica is denoted by sequence number 1 or 4. A genome DNA-derived polynucleotide for determining A. bicolor bicolor is denoted by sequence number 2 or 5. A genome DNA-derived polynucleotide for determining A. Anguilla is denoted by sequence number 3 or 7. A method for determining the Anguilla species comprises: a step of isolating DNA from Anguilla; a step of performing PCR using a primer of sequence number 8 and DNA as a template; a step of analyzing 500-600bp of PCR product length or base sequence among the PCR product; and a step of determining the Anguilla species.
Abstract translation: 目的：用于确定安圭拉粳稻品种的DNA标记和使用其确定安圭拉粳稻的方法，以区分国内安圭拉和外国安圭拉。 构成：用于确定安圭拉粳稻的基因组DNA衍生的多核苷酸由序列号1或4表示。用于确定双色双色的双基因组DNA衍生的多核苷酸由序列号2或5表示。用于测定的基因组DNA衍生的多核苷酸 A.安圭拉由序列号3或7表示。确定安圭拉物种的方法包括：从安圭拉分离DNA的步骤; 使用序列号8的引物和DNA作为模板进行PCR的步骤; 在PCR产物中分析500-600bp的PCR产物长度或碱基序列的步骤; 并确定安圭拉物种的一个步骤。
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