公开(公告)号：KR100864203B1

公开(公告)日：2008-10-17

申请号：KR1020070044570

申请日：2007-05-08

Applicant: 재단법인 제주테크노파크

Inventor： 김기옥 ,  이주엽 ,  한종헌 ,  김봉석 ,  강민철 ,  김미량 ,  고광효 ,  진호경 ,  김행범 ,  김세재

IPC: A61K8/97 ,  A61Q19/02

CPC classification number: A61K8/97 ,  A61K36/73 ,  A61Q19/02 ,  Y10S514/844 ,  Y10S514/857

Abstract: A composition comprising the extract of Malus micromalus Makino is provided to whiten the skin by inhibiting melanin biosynthesis and activity of tyrosinase, suppress oxidation and inflammation, and improve economical efficiency and safety of use by using natural plant. A composition for whitening the skin comprises the extract of Malus micromalus Makino which is prepared by washing leaf, branch, flower or fruit of Malus micromalus Makino with water, drying it with hot wind of 40 deg. C for 3 days, pulverizing the dried Malus micromalus Makino, dipping the pulverized Malus micromalus Makino in 70% ethanol and stirring it at room temperature for 2-3 days, filtering the stirred solution to obtain the crude extract of Malus micromalus Makino, and fractionating the crude extract with other solvent with different polarity.

Abstract translation: 通过抑制黑色素生物合成和酪氨酸酶的活性，抑制氧化和炎症，提高使用天然植物的经济效益和使用安全性，提供含有马蹄芥属提取物的组合物。 用于使皮肤美白的组合物包括通过用水洗涤马鞭草的叶子，分枝，花或果实制备的马蹄芥的提取物，用40℃的热风干燥。 3天，粉碎干燥的马蹄豆，将粉碎的Malus micromalus Makino浸在70％乙醇中并在室温下搅拌2-3天，过滤搅拌溶液，得到Malus micromalus Makino粗提物，分馏 粗提物与其他溶剂具有不同的极性。