Abstract:
본 발명은, 비목나무(Lindera erythrocarpa) 추출물, 이의 분획물, 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 약학적 조성물에 관한 것으로, 본 발명의 조성물은 PPAR-γ 길항제로서 암, 동맥경화, 류마티스 관절염, 다발성경화증, 알츠하이머 또는 비만의 예방 또는 치료에 유용하게 사용될 수 있다.
Abstract:
The extracts of the Ishigeaceae plant showing the antidiabetic activity is provided. A pharmaceutical composition comprising the extracts of the Ishigeaceae plant is provided to improve anti-diabetic and anti-oxidative activities. The Ishigeaceae plant extract for prevention and improvement of diabetes is obtained from the Ishigeaceae plant, and is prepared by washing Ishige sinicola; dipping the washed Ishige sinicola in 70% ethanol and agitating it at room temperature for 2-3 days; filtering the leached product of Ishige sinicola to prepare the crude extract; and sequentially fractioning the crude extract with n-hexane, ethylacetate, and butanol to obtain fractions.
Abstract:
본 발명은 미백활성 및 항염활성을 나타내는 비룡추출물에 관한 것이다. 본 발명의 비룡추출물은, 비룡( Poncirus
polyandra ) 미성숙 과실을 수세한 다음, 습식분쇄기로 분쇄하고, 이 분쇄물을 동결건조하여 분말을 제조하고, 분말을 70 % 에탄올에 침적시키고 2 ~ 3 일 동안 실온에서 교반하여 침출하고, 이 침출물을 여과기로 여과하고, 이 침출.여과과정을 2 ~ 3 회 더 반복한 다음, 이 여과액을 감압농축하고, 농축물을 증류수에 현탁시킨 후, 현탁액을 헥산, 에틸아세테이트, 부탄올로 순차적으로 추출하여 제조한다. 본 발명에 의해 미백활성, 항산화활성, 항염활성을 나타내는 비룡추출물이 제공되며, 본 발명의 비룡추출물을 유효성분으로 포함하는 미백용 화장료조성물이 제공되며, 염증질환의 예방 및 치료용 조성물이 제공된다. 비룡, 추출, 미백, 항산화, 항염
Abstract:
본 발명은, 비목나무(Lindera erythrocarpa) 추출물, 이의 분획물, 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 약학적 조성물에 관한 것으로, 본 발명의 조성물은 PPAR-γ 길항제로서 암, 동맥경화, 류마티스 관절염, 다발성경화증, 알츠하이머 또는 비만의 예방 또는 치료에 유용하게 사용될 수 있다.
Abstract:
PURPOSE: A Lindera erythrocarpa-derived compound is provided to obtain a composition for skin whitening showing melanin inhibitory activity higher than existing albutin known as a whitening agent. CONSTITUTION: A method for separating a Lindera erythrocarpa-derived compound comprises the steps of: extracting Lindera erythrocarpa in a solvent to obtain Lindera erythrocarpa extracts; partitioning the Lindera erythrocarpa extracts into hexane, methylene chloride, ethyl acetate, and butanol to obtain solvent fractions; partitioning the Lindera erythrocarpa extracts by performing a primary silicagel column chromatography using hexane and ethyl acetate as a solvent; and applying a secondary silica gel column chromatography to the extracts using a mixed solvent of hexane and ethyl acetate.
Abstract:
PURPOSE: A method for preparing Hedera rhombea extract which suppresses melanogenesis and tyrosinase activity is provided to treat melasma, dots, freckles, or hyperpigmentation during pregnancy. CONSTITUTION: A whitening cosmetic composition contains 25-100ug/ml of Hedera rhombea as an active ingredient. A method for preparing ethyl acetate from Hedera rhombea comprises: a step of washing and drying Hedera rhombea by hot air; a step of pulverizing Hedera rhombea; a step of precipitating pulverized Hedera rhombea in an organic solvent, leaching, and filtering; a step of repeating leaching and filtering two or three times; a step of decompressing and freeze-drying to obtain a powder; and a step of partitioning the Hedera rhombea extract with ethyl acetate. The organic solvent is 70% ethanol.
Abstract:
PURPOSE: A composition containing Aster subulatus extract for improving skin condition is provided to ensure anti-inflammatory effect through anti-oxidation, meganogenesis suppression, and NO generation suppression. CONSTITUTION: A composition for improving skin condition contains Aster subulatus extract or its solvent fraction as an active ingredient. The Aster subulatu extract is obtained by pulverizing dried Aster subulatu, dipping the pulverized Aster subulatu in 70% ethanol, stirring for 2-3 days, filtering, compress-concentrating, and freeze-drying. The solvent fraction is ethanol extract, hexane fraction, methylenechloride fraction, ethylacetate fraction, butanol fraction, water fraction, or their mixture. The composition for improving skin condition is for skin whitening or anti-inflammation. The composition is formulated in a cosmetic composition or pharmaceutical composition.