Abstract:
PURPOSE: A composition containing an alcohol extract of Albatrellus dispansus is provided to suppress cholesterol and neutral fat absorption, and to prevent or treat hyperlipidemia. CONSTITUTION: A composition for preventing or treating hyperlipidemia contains a C1-C10 alcohol extract of Albatrellus dispansus as an active ingredient. A pharmaceutical product for preventing or treating hyperlipidemia contains the extract as an active ingredient. A health functional food for preventing or treating hyperlipidemia contains the extract as an active ingredient. A method for preventing or treating hyperlipidemia comprises a step of administering the extract to animals exclusive of human. The extract suppresses blood cholesterol and/or neutral fat absorption. [Reference numerals] (AA) CEL activity inhibition(%); (BB) Water extract (Comparative example); (CC) Ethanol extract
Abstract:
본 발명은 Rheb(Ras homolog enriched in the brain) 및 튜불린(tubulin)의 상호작용에 의한 Rheb에 결합하는 뉴클레오티드의 조절 및 상기 조절을 통한 mTOR 활성과의 관계를 밝혀낸 연구 결과에 기초한 것으로, 구체적으로는 튜불린(tubulin)의 중합 또는 아세틸화 조절제를 유효성분으로 포함하여 Rheb(Ras homolog enriched in the brain)-GTP 복합체의 세포내 수준을 조절하는 것인 mTOR 활성 조절제 및 상기 활성 조절제의 검출 방법에 관한 것이다.
Abstract:
PURPOSE: A composition containing an alcohol extract of Oligoporus tephroleucus is provided to suppress absorption of cholesterol in body, and to prevent or treat hyperlipidemia. CONSTITUTION: A composition for preventing or treating hyperlipidemia contains a C1-C10 alcohol extract of Oligoporus tephroleucus as an active ingredient. A pharmaceutical product for preventing or treating hyperlipidemia contains the alcohol extract as an active ingredient. A health functional food for preventing or treating hyperlipidemia contains the alcohol extract as an active ingredient. A method for preventing or treating hyperlipidemia comprises a step of administering the alcohol extract to animals exclusive of human. The alcohol extract suppresses absorption of cholesterol in blood and esterase activity. The alcohol extract is prepared by extracting Oligoporus tephroleucus with 90-99.9%(v/v) ethanol at 20-60 deg. C for 12-36 hours. [Reference numerals] (AA) CEL inhibition %; (BB) Water extract; (CC) Ethanol extract
Abstract:
PURPOSE: A composition containing a water extract of Tremella foliacea Fr. is provided to suppress digestion and absorption of fat in the body, and to prevent or treat obesity. CONSTITUTION: A composition for preventing or treating obesity contains a water extract of Tremella foliacea Fr. as an active ingredient. A pharmaceutical product for preventing or treating obesity contains the water extract as an active ingredient. A health functional food for preventing or treating obesity contains the water extract as an active ingredient. A method for preventing or treating obesity comprises a step of administering the water extract to animals exclusive of human. The water extract suppresses activity of pancreatic lipase. The water extract is prepared from Tremella foliacea Fr. with water at 20-60 deg. C for 12-36 hours. [Reference numerals] (AA) TGL activity inhibition(%); (BB) Water extract; (CC) (Comparative example) Ethanol extract