公开(公告)号：KR1020140075188A

公开(公告)日：2014-06-19

申请号：KR1020120143289

申请日：2012-12-11

Applicant: 한국과학기술원

Inventor： 박인철 ,  이영주 ,  유호영 ,  정재환 ,  조지혁

IPC: G11C29/42 ,  H03M13/00

Abstract: A concatenated BCH encoding circuit includes a row encoder, a column encoder, and a parity FIFO buffer. The lower encoder performs first encoding in a row direction with respect to a plurality of data blocks forming one page and generates firs parities in parallel. The column encoder performs second encoding for each data block during the first encoding for the data blocks and generates partial parities in a column direction. The parity FIFO buffer stores the partial parities. The column encoder performs the second encoding in the column direction with respect to the data blocks by one read-out for the data blocks using the partial parities stored in the parity FIFO buffer and generates second parities.

Abstract translation: 级联的BCH编码电路包括行编码器，列编码器和奇偶校验FIFO缓冲器。 下编码器相对于形成一页的多个数据块在行方向上执行第一编码，并且并行地生成最小奇偶校验。 列编码器在数据块的第一编码期间对每个数据块执行第二编码，并在列方向上生成部分奇偶校验。 奇偶校验FIFO缓冲器存储部分奇偶校验。 列编码器使用存储在奇偶校验FIFO缓冲器中的部分奇偶校验，对于数据块对数据块执行对列数据方向的第二编码，并产生第二奇偶校验。

公开(公告)号：KR1020130056543A

公开(公告)日：2013-05-30

申请号：KR1020110122199

申请日：2011-11-22

Applicant: 한국과학기술원

Inventor： 서태석 ,  정재환

IPC: C12M1/34 ,  C12Q1/04 ,  C12M1/42

CPC classification number: B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01L3/50273 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2300/0806 ,  B01L2300/0883 ,  B01L2300/1827 ,  B01L2400/0409 ,  B01L2400/0421 ,  B01L2400/043 ,  B82Y5/00 ,  B82Y35/00 ,  G01N27/44726 ,  G01N27/44791 ,  G01N33/54326 ,  G01N33/54346 ,  G01N33/54366

Abstract: PURPOSE: A microdevice for detecting pathogens is provided to detect a pathogen from clinical and environmental samples by sample-in-answer-out capability, and to be applied in biostability test, environmental screening, and clinical test with quick analysis. CONSTITUTION: A microdevice for detecting pathogens comprises: a passive micromixer, a magnetic separation chamber, and a capillary electrophoresis channel. The passive micromixer is used for mixing pathogens, a first probe, and a second probe. The magnetic separation chamber is connected to the passive micromixer. The capillary electrophoresis channel is connected to the magnetic separation chamber. The first probe contains an MMP(magnetic microparticle) probe. The second probe contains nanoparticles of gold, silver, platinum, palladium, copper, nickel, zinc, silicon oxide, or polystyrene. [Reference numerals] (AA) Magnetic field; (BB) Barcode DNA; (CC) Magnetic separation & barcode DNA emission; (DD) Sample; (EE) Separation chamber; (FF) Cathode; (GG) Waste; (HH) Target pathogen capturing through a particle probe; (II) Inlet; (JJ) Manual mixer; (KK) CE channel; (LL) Pathogen detection; (MM) Anode; (NN) Particle probe; (OO) Pathogen; (PP) MMP with the surface on which an antibody is immobilized; (QQ) Magnet; (RR) AuNP modified with FAM tagged barcode DNA and antibody

Abstract translation: 目的：提供用于检测病原体的微型装置，通过采样应答能力检测临床和环境样品中的病原体，并通过快速分析应用于生物稳定性试验，环境筛选和临床试验。 构成：用于检测病原体的微型装置包括：无源微混合器，磁分离室和毛细管电泳通道。 被动微混合器用于混合病原体，第一探针和第二探针。 磁分离室连接到无源微混合器。 毛细管电泳通道连接到磁分离室。 第一个探针含有一个MMP（磁性微粒）探针。 第二探针含有金，银，铂，钯，铜，镍，锌，氧化硅或聚苯乙烯的纳米颗粒。 （标号）（AA）磁场; （BB）条码DNA; （CC）磁分离和条形码DNA排放; （DD）样品; （EE）分离室; （FF）阴极; （GG）废物; （HH）通过粒子探针捕获目标病原体; （二）入口; （JJ）手动搅拌机; （KK）CE通道; （LL）病原体检测; （MM）阳极; （NN）粒子探针; （OO）病原体; （PP）MMP，其上固定抗体的表面; （QQ）磁铁; （RR）AuNP用FAM标记的条形码DNA和抗体修饰

公开(公告)号：KR1020120039565A

公开(公告)日：2012-04-25

申请号：KR1020120005179

申请日：2012-01-17

Applicant: 한국과학기술원

Inventor： 서태석 ,  정재환 ,  박병현

IPC: C12M1/38 ,  C12M1/34 ,  C12Q1/68

CPC classification number: B01L3/502753 ,  B01L2200/10 ,  B01L2400/0409 ,  C12M1/38 ,  C12Q1/6806 ,  C12Q1/686

Abstract: PURPOSE: A PCR pretreatment device and a method for pretreatment of a sample using the same are provided to effectively isolate and purify a target material. CONSTITUTION: A PCR pretreatment device comprises: a sample chamber for storing a sample solution, a washing buffer chamber for storing washing buffer solution, an elution buffer chamber, and a hydrophobic channel which is connected to each chamber and helps the flow of a solution. The kind of the solution is determined by rotation speed of a PCR chip.

Abstract translation: 目的：提供PCR预处理装置和使用其的预处理方法以有效地分离和纯化目标材料。 构成：PCR预处理装置包括：用于存储样品溶液的样品室，用于存储洗涤缓冲溶液的洗涤缓冲室，洗脱缓冲室和连接到每个室并且帮助溶液流动的疏水通道。 溶液的种类由PCR芯片的旋转速度决定。

公开(公告)号：KR1020120031188A

公开(公告)日：2012-03-30

申请号：KR1020120005180

申请日：2012-01-17

Applicant: 한국과학기술원

Inventor： 서태석 ,  정재환 ,  박병현

IPC: C12M1/38 ,  C12Q1/68

CPC classification number: B01L3/502753 ,  B01L2200/10 ,  B01L2400/0409 ,  C12M1/38 ,  C12Q1/6806 ,  C12Q1/686

Abstract: PURPOSE: A rotational polymerase chain reaction(PCR) apparatus and real-time polymerase chain reaction method using thereof are provided to implement of high yield PCR process with low cost. CONSTITUTION: A rotational polymerase chain reaction(PCR) apparatus comprises PCR chip which PCR is process, rotating tool which is connected to the PCR chip in order to rotate the PCR chip, and PCR temperature field formation tool(100) which is separated from the PCR chip to apply heat energy and is structured for PCR chip to pass by different temperature sections. The temperature field formation tool is a disc shaped and includes a plurality of heating blocks(100a, 100b, 100c). The heating blocks are heated with electric energy and a plurality of heating blocks is independently controllable. The heating blocks comprise light source which generates optical energy. The heating blocks include at least one of heating block groups consisting of unit heating block of 3. The heating block groups are 2 or more.

Abstract translation: 目的：提供旋转聚合酶链反应（PCR）装置及其使用的实时聚合酶链反应方法，以低成本实现高产率PCR过程。 构成：旋转聚合酶链反应（PCR）装置包括PCR过程的PCR芯片，连接到PCR芯片的旋转工具以旋转PCR芯片，以及PCR温度场形成工具（100），其与 PCR芯片应用热能，并被构建用于PCR芯片通过不同温度段。 温度场形成工具是盘形的并且包括多个加热块（100a，100b，100c）。 加热块用电能加热，多个加热块是可独立控制的。 加热块包括产生光能的光源。 加热块包括由3个单元加热块组成的加热块组中的至少一个。加热块组为2个或更多个。