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公开(公告)号：KR1020130074166A
公开(公告)日：2013-07-04
申请号：KR1020110142071
申请日：2011-12-26
Applicant: 한국전기연구원
IPC: G01N33/533 , G01N33/52 , G01N21/64
Abstract: PURPOSE: A biochip is provided to separate a fluorescence-releasing side from a substrate and to improve fluorescence detection performance. CONSTITUTION: A biochip (10) comprises: a substrate (20) with a predetermined thickness; a total reflection control unit (30) which is protruded from the lower side of the substrate and regulates the incidence angle of an excitation light (el); and a coating layer (40) which is formed to have a predetermined pattern on the upper side of the substrate. The total reflection control unit is formed to have a predetermined angle between the lower side of the total reflection control unit and the lower side of the substrate in order for the excitation light to be totally reflected on the lower side (M1) of the substrate.
Abstract translation: 目的：提供生物芯片以将荧光释放侧与底物分离并提高荧光检测性能。 构成：生物芯片（10）包括：具有预定厚度的基底（20）; 全反射控制单元（30），其从基板的下侧突出并调节激发光（el）的入射角; 以及在基板的上侧形成为具有规定图案的被覆层（40）。 全反射控制单元形成为在全反射控制单元的下侧和基板的下侧之间具有预定角度，以使激发光在基板的下侧（M1）上被全反射。
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公开(公告)号：KR1020130057543A
公开(公告)日：2013-06-03
申请号：KR1020110123307
申请日：2011-11-24
Applicant: 한국전기연구원
CPC classification number: B22F9/24 , B22F1/0018 , B22F2301/255 , B82Y5/00 , B82Y40/00
Abstract: PURPOSE: A manufacturing method of a gold nanoparticle is provided to use biocompatible polymer as a reducing agent, sodium citrate as a pH controlling agent, microwave as a heating source and offers the same size and form and manufactures quickly a gold nanoparticle which is spread. CONSTITUTION: A manufacturing method of a gold nanoparticle comprises the following steps. A solution mixed with biocompatible polymer, gold salt and a pH controlling agent is heated to be reacted. In the solution, the biocompatible polymer covering a gold ion is decomposed to become a radical. The radical accelerates the reduction of the gold ion to manufacture a gold nanoparticle. The biocompatible polymer capped on the gold nanoparticle prevents the gold nanoparticles from being stuck together. An increase in pH caused by the addition of sodium citrate which is the pH controlling agent allows the lowering of the reacting speed of the gold salt to control the size and the uniformity of the gold nanoparticle. The biocompatible polymer comprises polyvinylpyrrolidone(PVP) or polyethylene glycol(PEG).
Abstract translation: 目的：提供金纳米颗粒的制造方法，使用生物相容性聚合物作为还原剂，柠檬酸钠作为pH控制剂，微波作为加热源，并提供相同尺寸并形成并快速制造扩散的金纳米颗粒。 构成：金纳米颗粒的制造方法包括以下步骤。 将与生物相容性聚合物，金盐和pH控制剂混合的溶液加热反应。 在溶液中，覆盖金离子的生物相容性聚合物被分解成基团。 该基团加速金离子的还原以制造金纳米颗粒。 覆盖在金纳米颗粒上的生物相容性聚合物防止金纳米颗粒粘在一起。 通过添加作为pH控制剂的柠檬酸钠引起的pH的增加允许降低金盐的反应速度以控制金纳米颗粒的尺寸和均匀性。 生物相容性聚合物包括聚乙烯吡咯烷酮（PVP）或聚乙二醇（PEG）。
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公开(公告)号：KR101141039B1
公开(公告)日：2012-05-03
申请号：KR1020080129851
申请日：2008-12-19
Applicant: 한국전기연구원
Abstract: PURPOSE: A manufacturing method of the capillary tube valve for the lab on a chip is provided to maintain independent reaction and detection of plural reaction chambers. CONSTITUTION: A lab on a chip having a capillary tube valve: comprises: inserted sample and a plurality of reaction chambers. In a plurality of reaction chambers, the reagent implantation part in which reagent is inserted is formed and it is connected to the micro channel in which reagent flows. In a plurality of reaction chambers, the reagent implantation part in which reagent is inserted is formed and it is connected to the micro channel in which reagent flows. The capillary tube valve for secluding the flow of microfluid is formed on the reagent implantation part.
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公开(公告)号：KR1020110068054A
公开(公告)日：2011-06-22
申请号：KR1020090124879
申请日：2009-12-15
Applicant: 한국전기연구원
Inventor： 이경희
IPC: G01N21/64 , G01N33/483
Abstract: PURPOSE: A biochemical material detecting apparatus using fluorescence is provided to reduce the measurement error caused by the dispersion and reflection of light irradiated from a light source and to simplify a structure. CONSTITUTION: A biochemical material detecting apparatus using fluorescence comprises: a light source(30) coupled to one spot inside a body unit(20); a fluorescence signal generation unit(40) inputted with a detector, which reacts to sample and detects a biochemical material, to make the sample and the detector react to each other and to generate fluorescence signals from the sample and the detector reacted by light irradiated from the light source; and a fluorescence signal detection unit(50) spaced out from the fluorescence signal generation unit and coupled to the inside of the body unit to detect the fluorescence signals irradiated from the fluorescence signal generation unit.
Abstract translation: 目的：提供使用荧光的生化材料检测装置，以减少由光源照射的光的分散和反射引起的测量误差，并简化结构。 构成：使用荧光的生化材料检测装置包括：耦合到体单元（20）内的一个点的光源（30）; 输入检测器的荧光信号生成单元（40），其对样品进行反应并检测生物化学物质，使得样品和检测器彼此反应并产生来自样品和检测器的荧光信号，所述荧光信号由来自 光源; 以及荧光信号检测单元（50），其与所述荧光信号生成单元间隔开并耦合到所述身体单元的内部，以检测从所述荧光信号生成单元照射的荧光信号。
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Patent Agency Ranking
公开(公告)号：KR1020100071217A
公开(公告)日：2010-06-29
申请号：KR1020080129851
申请日：2008-12-19
Applicant: 한국전기연구원
CPC classification number: B01L3/5027 , B01L3/502738 , B01L2400/0406 , B01L2400/0622 , B01L2400/0677 , B01L2400/0683
Abstract: PURPOSE: A manufacturing method of the capillary tube valve for the lab on a chip is provided to maintain independent reaction and detection of plural reaction chambers. CONSTITUTION: A lab on a chip having a capillary tube valve: comprises: inserted sample and a plurality of reaction chambers. In a plurality of reaction chambers, the reagent implantation part in which reagent is inserted is formed and it is connected to the micro channel in which reagent flows. In a plurality of reaction chambers, the reagent implantation part in which reagent is inserted is formed and it is connected to the micro channel in which reagent flows. The capillary tube valve for secluding the flow of microfluid is formed on the reagent implantation part.
Abstract translation: 目的：提供一种用于芯片实验室毛细管阀的制造方法，以保持多个反应室的独立反应和检测。 构成：具有毛细管阀的芯片上的实验室包括：插入的样品和多个反应室。 在多个反应室中，形成插入有试剂的试剂注入部，并与试剂流动的微通道连接。 在多个反应室中，形成插入有试剂的试剂注入部，并与试剂流动的微通道连接。 用于隔离微流体流动的毛细管阀形成在试剂注入部分上。
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公开(公告)号：KR1020100060723A
公开(公告)日：2010-06-07
申请号：KR1020080119446
申请日：2008-11-28
Applicant: 한국전기연구원
CPC classification number: B81B3/0018 , B81B7/02 , B81B2201/031 , B81B2201/036
Abstract: PURPOSE: A micro-pump for a lab-on-a-chip and a manufacturing method thereof are provided to simplify the configuration of a lab-on-a-chip by carrying a fluid in a micro-channel through expansion and contraction of thermo-sensitive polymer. CONSTITUTION: A micro-pump(200) for a lab-on-a-chip comprises a micro-channel. The micro-channel comprises a capillary tube(210), thermo-sensitive polymer(250), and a temperature controller. The capillary tube has an inlet on one side and an outlet on the other which a micro-fluid flows in and out. The thermo-sensitive polymer is fixed along the inner surface of the capillary tube. The temperature controller is located on the outer surface of the capillary tube and the micro-channel which contacts with the capillary tube and heats the thermo-sensitive polymer.
Abstract translation: 目的：提供一种用于芯片实验室的微型泵及其制造方法，以通过在微通道中通过热膨胀和收缩来携带流体来简化芯片实验室的配置 敏感聚合物。 构成：用于芯片实验室的微型泵（200）包括微通道。 微通道包括毛细管（210），热敏聚合物（250）和温度控制器。 毛细管具有一侧的入口和另一个微流体流入和流出的出口。 热敏聚合物沿着毛细管的内表面固定。 温度控制器位于毛细管的外表面和与毛细管接触并加热热敏聚合物的微通道。
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公开(公告)号：KR1020080098248A
公开(公告)日：2008-11-07
申请号：KR1020070043687
申请日：2007-05-04
Applicant: 한국전기연구원
Abstract: A hyperspectral polarization imaging apparatus is provided to obtain a precise optical image by applying the Muller matrix(Mueller matrix) technique and technique(hyperspectral imaging) to the conventional method using only image. In a hyperspectral polarization imaging apparatus, a first polarization element(303) converts laser from the light source(101) into the polarization light having the polarization surface of the first angle. A first rotating device(304) rotates the polarization surface of the polarization light and projects polarization light to the organism(300). A second rotating device(307) rotates the polarization light reflected from organism. A second polarization device(105) restores the polarization surface of the second angle into an original light. A wavelength conversion filter(106) divides the optic signal wavelength reflected from organism and outputs a plurality of divided optical signals. A camera(309) obtains a plurality of images for diagnosing based on a plurality of divided optical signal and obtains Muller matrix operation person having the horizontal, vertical, and rotation component of the polarized light according to the state of polarization light.
Abstract translation: 提供了一种高光谱偏振成像装置，通过将Muller矩阵（Mueller矩阵）技术和技术（超光谱成像）应用于仅使用图像的常规方法来获得精确的光学图像。 在高光谱偏振成像装置中，第一偏振元件（303）将来自光源（101）的激光转换成具有第一角度的偏振面的偏振光。 第一旋转装置（304）使偏振光的偏振面旋转并将偏振光投影到生物体（300）。 第二旋转装置（307）使从生物反射的偏振光旋转。 第二偏振装置（105）将第二角度的偏振面恢复成原始光。 波长转换滤波器（106）对从生物体反射的光信号波长进行分割，并输出多个分割的光信号。 相机（309）根据多个划分的光信号获得多个用于诊断的图像，并且根据偏振光的状态获得具有偏振光的水平，垂直和旋转分量的Muller矩阵运算人。
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公开(公告)号：KR1020050102264A
公开(公告)日：2005-10-26
申请号：KR1020040027447
申请日：2004-04-21
Applicant: 한국전기연구원
Inventor： 이경희 , 보즈네센스키니코레이비 , 키릴로브스키브라미디르케이
IPC: G01N21/45
CPC classification number: G01M11/005 , G01M11/0271 , G01B9/02007 , G01N21/95607
Abstract: 본 발명은 렌즈 및 거울 등 광학 부품의 표면 지형을 측정하기 위한 점회절 간섭계 장치에 관한 것이다. 본 발명은 압전 소자가 장착된 시준기를 구비한 점회절 간섭계 장치를 제공한다. 상기 시준기에 장착된 압전 소자는 검출기에서 검출된 간섭 무늬 패턴의 선명도에 근거하여 실시간으로 구동된다. 이에 따라, 높은 선명도의 간섭 무늬 패턴을 얻을 수 있으며 측정 정밀도가 개선된다. 또한, 간섭상 중심 측정기에 의한 압전 소자의 구동은 실시간으로 이루어지기 때문에 미세한 진동 등 원하지 않은 오차 발생 요인에 대해서 효율적으로 대처할 수 있으며, 신뢰성 있는 점회절 간섭계 장치를 제공할 수 있다.
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公开(公告)号：KR100276249B1
公开(公告)日：2000-12-15
申请号：KR1019980033176
申请日：1998-08-10
IPC: H01M10/05
CPC classification number: H01M10/052 , H01M10/0565
Abstract: 본 발명은 리튬 폴리머 2차전지용 고분자 전해질 제조방법에 관한 것으로서, 에틸렌 카보네이트(EC:Ethylene Carbonate)/프로필렌 카보네이트(PC: Propylene Carbonate) (50/50 vol %) 용매에 1 몰의 LiClO
4 이 용해된 액체 전해액(70)이 담겨있는 용기(60)내에, 폴리비닐리딘 플루오라이드(Polyvinylidene fluoride) 필름(80)을 상온에서 1시간 동안 함침시킨 후, 필름 표면의 전해액을 제거하여 고분자 전해질을 제조함으로써, 비교적 간단한 공정과 장치만으로 제조가 가능하며, 별도의 용매를 사용하지 않으므로 용매의 건조와 같은 공정이 필요치 않아 보다 짧은 시간내에 제조가 가능한 것은 물론, 비용이 적게 들고 공해 문제를 발생시키지 않아 환경친화적인 매우 유용한 발명이다.Abstract translation: 目的：提供高聚合物电解质形成方法简单且成本低廉。 构成：用于形成二次锂聚合物电池的高分子电解质的方法包括以下步骤：通过使用极性大的偶极矩的高分子材料制备高分子膜; 并且在预定时间内将高分子膜浸渍在与高分子膜具有大亲合力的锂苏打中制成高分子电解质，其中在步骤1中将电解质在30℃至60℃的范围内加热 制成高分子电解质。
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