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    CULTURE DEVICE FOR LACTIC ACID BACTERIA
    21.
    发明申请
    CULTURE DEVICE FOR LACTIC ACID BACTERIA 审中-公开
    用于酸乳杆菌的培养装置

    公开(公告)号：WO2016176173A1

    公开(公告)日：2016-11-03

    申请号：PCT/US2016/029303

    申请日：2016-04-26

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： BJORK, Jason W. ,  BRUTINEL, Evan D. ,  STANENAS, Adam J.

    IPC: C12M1/12 ,  C12M1/34 ,  C12Q1/06 ,  C12M1/00 ,  C12Q1/04

    CPC classification number: C12M25/06 ,  C12M23/04 ,  C12M23/20 ,  C12M41/34 ,  C12M41/36 ,  C12Q1/04

    Abstract: The present disclosure provides a culture device for enumerating colonies of microorganisms. The device can comprise a base, a coversheet, and a nonporous spacer member disposed therebetween. The spacer member comprises an aperture that defines a growth compartment. Disposed in the growth compartment are a cold water-soluble gelling agent, a dry oxygen-scavenging reagent, a dry buffer system, and an effective amount of a dry carbon dioxide-generating reagent. The buffer system is selected such that, when the growth compartment is hydrated with a predetermined volume of deionized water, an aqueous mixture with a pH less than or equal to 6.35 is formed.

    Abstract translation: 本公开提供了一种用于列举微生物菌落的培养装置。 该装置可以包括底座，覆盖片和设置在它们之间的无孔隔离构件。 间隔构件包括限定生长室的孔。 在生长室中配置有冷水溶性胶凝剂，干燥氧清除剂，干燥缓冲系统和有效量的产生干燥二氧化碳的试剂。 选择缓冲系统，使得当生长室与预定体积的去离子水水合时，形成pH小于或等于6.35的含水混合物。

    CAP HANDLING TOOLS AND METHODS OF USE
    22.
    发明申请
    CAP HANDLING TOOLS AND METHODS OF USE 审中-公开
    CAP处理工具和使用方法

    公开(公告)号：WO2013019912A1

    公开(公告)日：2013-02-07

    申请号：PCT/US2012/049242

    申请日：2012-08-02

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  BARTHOLOMEW, Cheryl A. ,  BJORK, Jason W. ,  PERCY, Neil ,  SITTON, Gregory W.

    Inventor： BARTHOLOMEW, Cheryl A. ,  BJORK, Jason W. ,  PERCY, Neil ,  SITTON, Gregory W.

    IPC: B25B9/00 ,  B01L9/00 ,  B01L99/00

    CPC classification number: B67B7/02 ,  B01L3/50853 ,  B01L3/50855 ,  B01L9/00 ,  B01L99/00 ,  B25B33/00 ,  B67B1/045

    Abstract: Tools (100) are provided for use in uncapping one or more of a plurality of linearly-oriented, spaced-apart tubes; each cap having a cap upper surface with a depression. The tools comprise a body (30) having first portion (40) for engagement by a user and a second portion (50) for engaging a plurality of caps. The second portion comprises a plurality of spaced-apart projections (60). Each projection is configured for releasably engaging a cap. The projection may comprise two or more spaced-apart projection elements (62,64). Optionally, the first portion is configured in a non- coplanar relationship with respect to the second portion. Methods of use are also provided.

    Abstract translation: 工具（100）被提供用于打开多个线性取向的间隔开的管中的一个或多个管; 每个盖具有带有凹陷的盖上表面。 工具包括具有用于与使用者接合的第一部分（40）和用于接合多个盖的第二部分（50）的主体（30）。 第二部分包括多个间隔开的突起（60）。 每个突起构造成可释放地接合盖。 突起可以包括两个或更多个间隔开的投影元件（62,64）。 可选地，第一部分被配置成相对于第二部分的非共面关系。 还提供了使用方法。

    FIBRIN COMPOSITION, METHOD AND WOUND ARTICLES
    24.
    发明公开
    FIBRIN COMPOSITION, METHOD AND WOUND ARTICLES 审中-公开
    纤维蛋白组合物，方法和伤口制品

    公开(公告)号：EP3274002A1

    公开(公告)日：2018-01-31

    申请号：EP16714195.1

    申请日：2016-03-25

    Applicant: 3M Innovative Properties Company

    Inventor： BJORK, Jason W. ,  YOUNG, Alexi J. ,  BEEN, Raha A. ,  NINKOVIC, Jana ,  BAKER, Bryan A.

    IPC: A61L24/10

    CPC classification number: A61L26/008 ,  A61F13/0259 ,  A61F2013/00089 ,  A61F2013/00655 ,  A61F2013/00676 ,  A61F2013/00706 ,  A61L24/106 ,  A61L26/0042 ,  A61L26/0071

    Abstract: A method of forming a fibrin hydrogel composition is described. The method comprises forming an aqueous solution comprising fibrinogen, fibrin-forming enzyme, and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further comprises reducing the salt concentration below the threshold concentration to form a fibrin hydrogel. In some embodiments, the aqueous solution further comprises a plasticizer. A fibrin composition is also described comprising a fibrin hydrogel having a fibrin concentration ranging from 0.1 to 10 wt-%; and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt has a concentration less than a threshold concentration to form the fibrin hydrogel. The fibrin hydrogel or dehydrated fibrin hydrogel can be in various physical forms such a sheet, foam, or plurality of pieces. Also described are methods of forming a fibrin article, wound dressings and a method of treatment of a wound.

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