公开(公告)号：ES2351337T3

公开(公告)日：2011-02-03

申请号：ES04010960

申请日：1994-09-22

Applicant: ABBOTT LAB

Inventor： TAYI APPARAO ,  MITCHELL JAMES E ,  HANCE ROBERT B ,  WATKINS WILLIAM E III ,  CLARK FREDERICK L ,  MCDOWELL DOUGLAS D ,  RAYMOURE WILLIAM J ,  HILLS DAVID B ,  CLIFT GILBERT ,  STANTON ALYN K ,  SPRONK ADRIAN M ,  KANEWSKE WILLIAM J III ,  MARTIN RICHARD R ,  VAUGHT JAMES A ,  OLEKSAK CARL M ,  HENDRICK KENDALL B ,  SCHRIER PAUL R ,  PENNINGTON CHARLES D ,  MOORE LARRY W ,  CLEMENS JOHN M ,  WALKER EDNA S ,  SMITH JANE B ,  CLOONAN KEVIN M ,  WOHLFORD ROBERT A ,  WALKER DONNY RAY ,  YOST DAVID A ,  MERRIAM RICHARD A ,  SCHMIDT LINDA S ,  VICKSTROM RICHARD L ,  LAGOCKI PETER A ,  WINTER GARY E ,  RUMBAUGH WILLIAM D

IPC: G01N33/483 ,  G01N35/02 ,  B01F11/00 ,  B01L3/00 ,  B29C45/00 ,  G01F23/22 ,  G01F23/26 ,  G01N1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  G01N33/53 ,  G01N33/542 ,  G01N33/543 ,  G01N33/553 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10 ,  H01J49/04

Abstract: Un método para realizar simultáneamente al menos dos análisis, comprendiendo dichos análisis una pluralidad de actividades, para una pluralidad de muestras líquidas en un sistema analítico continuo, comprendiendo dicho método las etapas de: combinar una alícuota de una primera muestra líquida con al menos un reactivo en un primer contenedor de reacción para formar una primera mezcla de reacción de análisis para dicha primera muestra líquida; combinar una alícuota de una segunda muestra líquida con al menos un reactivo en un segundo contenedor de reacción para formar una segunda mezcla de reacción de análisis para dicha segunda muestra líquida; incubar dichas primera y dicha segunda mezcla de reacción de análisis al menos un tiempo; realizar las actividades asociadas con cada análisis distintas de dicha combinación y dicha incubación de la primera y la segunda mezclas de reacción de análisis para completar cada análisis, incluyendo dichas otras actividades analizar las mezclas de reacción de análisis incubadas; y programar las etapas de dicha combinación, dicha incubación, y dichas actividades de realización distintas de dicha combinación y dicha incubación asociadas con cada uno de los análisis de acuerdo con un protocolo predeterminado, especificando dicho protocolo: (a) qué actividades se van a realizar para un análisis dado; (b) el orden en el que se van a realizar dichas actividades de (a); (c) al menos un período de incubación entre dichas actividades de (a), comprendiendo dicho al menos un período de incubación un período nominal de tiempo para la realización de una etapa de incubación entre las actividades de (a) y una ventana de tiempo especificada para añadirla o restarla al período de incubación nominal para variar la duración del período nominal entre las actividades de (a) para optimizar el funcionamiento; (d) cómo se van a realizar dichas actividades de (a); y (e) la duración de dichas actividades de (a).

公开(公告)号：DE69434702D1

公开(公告)日：2006-05-24

申请号：DE69434702

申请日：1994-09-22

Applicant: ABBOTT LAB

Inventor： CLARK FREDERICK L ,  CLEMENS JOHN M ,  HANCE ROBERT B ,  HENDRICK KENDALL B ,  TAYI APPARAO ,  KANEWSKE WILLIAM J III ,  LAGOCKI PETER A ,  MARTIN RICHARD R ,  MCDOWELL DOUGLAS D ,  MERRIAM RICHARD A ,  MOORE LARRY W ,  OLEKSAK CARL M ,  PENNINGTON CHARLES D ,  RAYMOURE WILLIAM J ,  RUMBAUGH WILLIAM D ,  SCHMIDT LINDA S ,  SCHRIER PAUL R ,  SMITH B JANE ,  SPRONK ADRIAN M ,  WALKER EDNA S ,  VAUGHT JAMES A ,  VICKSTROM RICHARD L ,  WALKER DONNY RAY ,  WATKINS WILLIAM E III ,  WINTER GARY E ,  WOHLFORD ROBERT A ,  CLIFT GILBERT ,  CLOONAN KEVIN M ,  MITCHELL JAMES E ,  STANTON ALYN K ,  YOST DAVID A ,  HILLS DAVID B

IPC: G01N33/483 ,  G01N35/10 ,  B01F11/00 ,  B01L3/00 ,  B29C45/00 ,  G01F23/22 ,  G01F23/26 ,  G01F23/284 ,  G01N1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  G01N33/53 ,  G01N33/542 ,  G01N33/543 ,  G01N33/553 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  H01J49/04

Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.

公开(公告)号：DE69434638D1

公开(公告)日：2006-04-27

申请号：DE69434638

申请日：1994-09-22

Applicant: ABBOTT LAB

Inventor： CLARK FREDERICK L ,  CLEMENS JOHN M ,  HANCE ROBERT B ,  HENDRICK KENDALL B ,  TAYI APPARAO ,  KANEWSKE WILLIAM J III ,  LAGOCKI PETER A ,  MARTIN RICHARD R ,  MCDOWELL DOUGLAS D ,  MERRIAM RICHARD A ,  MOORE LARRY W ,  OLEKSAK CARL M ,  PENNINGTON CHARLES D ,  RAYMOURE WILLIAM J ,  RUMBAUGH WILLIAM D ,  SCHMIDT LINDA S ,  SCHRIER PAUL R ,  SMITH B JANE ,  SPRONK ADRIAN M ,  WALKER EDNA S ,  VAUGHT JAMES A ,  VICKSTROM RICHARD L ALGONQUIN ,  WALKER DONNY RAY ,  WATKINS WILLIAM E III ,  WINTER GARY E ,  WOHLFORD ROBERT A ,  CLIFT GILBERT ,  CLOONAN KEVIN M ,  MITCHELL JAMES E ,  STANTON ALYN K ,  YOST DAVID A ,  HILLS DAVID B

IPC: G01N33/483 ,  G01N35/02 ,  B01F11/00 ,  B01L3/00 ,  B29C45/00 ,  G01F23/22 ,  G01F23/26 ,  G01N1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  G01N33/53 ,  G01N33/542 ,  G01N33/543 ,  G01N33/553 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10 ,  H01J49/04

Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.

公开(公告)号：AT319096T

公开(公告)日：2006-03-15

申请号：AT00108051

申请日：1994-09-22

Applicant: ABBOTT LAB

Inventor： CLARK FREDERICK L ,  CLEMENS JOHN M ,  HANCE ROBERT B ,  HENDRICK KENDALL B ,  TAYI APPARAO ,  KANEWSKE WILLIAM J III ,  LAGOCKI PETER A ,  MARTIN RICHARD R ,  MCDOWELL DOUGLAS D ,  MERRIAM RICHARD A ,  MOORE LARRY W ,  OLEKSAK CARL M ,  PENNINGTON CHARLES D ,  RAYMOURE WILLIAM J ,  RUMBAUGH WILLIAM D ,  SCHMIDT LINDA S ,  SCHRIER PAUL R ,  SMITH B JANE ,  SPRONK ADRIAN M ,  WALKER EDNA S ,  VAUGHT JAMES A ,  VICKSTROM RICHARD L ,  WALKER DONNY RAY ,  WATKINS WILLIAM E III ,  WINTER GARY E ,  WOHLFORD ROBERT A ,  CLIFT GILBERT ,  CLOONAN KEVIN M ,  MITCHELL JAMES E ,  STANTON ALYN K ,  YOST DAVID A ,  HILLS DAVID B

IPC: G01N33/483 ,  B01F11/00 ,  B01L3/00 ,  B29C45/00 ,  G01F23/22 ,  G01F23/26 ,  G01N1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  G01N33/53 ,  G01N33/542 ,  G01N33/543 ,  G01N33/553 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  H01J49/04

Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.

公开(公告)号：CA2362531A1

公开(公告)日：1995-03-30

申请号：CA2362531

申请日：1994-09-22

Applicant: ABBOTT LAB

Inventor： KANEWSKE WILLIAM J III ,  VICKSTROM RICHARD L ,  CLIFT GILBERT ,  CLEMENS JOHN M ,  WATKINS WILLIAM E III ,  SMITH B JANE ,  WALKER EDNA S ,  TAYI APPARAO ,  HENDRICK KENDALL B ,  CLARK FREDERICK L ,  WALKER DONNY RAY ,  STANTON ALYN K ,  MITCHELL JAMES E ,  CLOONAN KEVIN M ,  SPRONK ADRIAN M ,  HANCE ROBERT B ,  YOST DAVID A ,  HILLS DAVID B ,  LAGOCKI PETER A ,  SCHMIDT LINDA S ,  SCHRIER PAUL R ,  MERRIAM RICHARD A ,  MOORE LARRY W ,  WINTER GARY E ,  OLEKSAK CARL M ,  RAYMOURE WILLIAM J ,  PENNINGTON CHARLES D ,  RUMBAUGH WILLIAM D ,  WOHLFORD ROBERT A ,  VAUGHT JAMES A ,  MCDOWELL DOUGLAS D ,  MARTIN RICHARD R

IPC: G01N33/483 ,  B01F11/00 ,  B01L3/00 ,  B29C45/00 ,  G01F23/22 ,  G01F23/26 ,  G01N1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/76 ,  G01N21/78 ,  G01N33/53 ,  G01N33/542 ,  G01N33/543 ,  G01N33/553 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  H01J49/04

Abstract: An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.