公开(公告)号：EP1631570A1

公开(公告)日：2006-03-08

申请号：EP03723732.8

申请日：2003-03-12

Applicant: ABBOTT LABORATORIES

Inventor： ANDERSON, David ,  BEUTEL, Bruce ,  BOSSE, Todd, D. ,  CLARK, Richard ,  COOPER, Curt ,  DANDLIKER, Peter ,  DAVID, Caroline ,  GU, Yu-Gui ,  HANSEN, Todd, Matthew ,  HINMAN, Mira ,  KALVIN, Douglas ,  LARSON, Daniel, P. ,  LYNCH, Linda ,  MA, Zhenkun ,  MOTTER, Christopher ,  PALAZZO, Fabio ,  ROSENBERG, Teresa ,  REHM, Tamara ,  SANDERS, William ,  TUFANO, Michael ,  WAGNER, Rolf ,  WEITZBERG, Moshe ,  YONG, Hong ,  ZHANG, Tianyuan

IPC: C07D471/04 ,  A61K31/435 ,  A61P31/04

CPC classification number: C07D471/04

Abstract: Antibacterials having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.

公开(公告)号：EP1259923B1

公开(公告)日：2005-12-14

申请号：EP01920147.4

申请日：2001-02-23

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  NEMOTO, Peter, A. ,  ZHANG, Souming ,  YONG, Hong ,  OR, Yat, Sun

IPC: C07H17/08 ,  A61K31/7048 ,  A61P31/04

CPC classification number: A61K31/335

Abstract: The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-resistant Staphylococcus aureus (MRSA). Methods for inhibiting the activity of multi-drug resistant bacterial organisms and methods for treating a bacterial infection caused by such organisms are described herein.

公开(公告)号：EP1501846A1

公开(公告)日：2005-02-02

申请号：EP03731049.7

申请日：2003-04-25

Applicant: Abbott Laboratories

Inventor： GU, Yugui ,  MA, Zhenkun ,  YONG, Hong

IPC: C07H17/08 ,  A61K31/7048 ,  A61P31/04

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

公开(公告)号：EP1259923A2

公开(公告)日：2002-11-27

申请号：EP01920147.4

申请日：2001-02-23

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  NEMOTO, Peter, A. ,  ZHANG, Souming ,  YONG, Hong ,  OR, Yat, Sun

IPC: G06F17/60

CPC classification number: A61K31/335

Abstract: The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-resistant Staphylococcus aureus (MRSA). Methods for inhibiting the activity of multi-drug resistant bacterial organisms and methods for treating a bacterial infection caused by such organisms are described herein.