公开(公告)号：MY126592A

公开(公告)日：2006-10-31

申请号：MYPI20003409

申请日：2000-07-26

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12N15/09 ,  C12N15/53 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/70 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/06 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19

Abstract: THE INVENTION RELATE NOVEL CYTOCHROME P450 MONOXYGENASES WITH ALTERED SUBSTRATE SPECIFY WHICH ARE CAPABLE OF THE OXIDATION OF ORGANIC COMPOUNDS AS , FOR EXAMPLE, N-HETEROCYCLIC AROMATIC COMPOUNDS, NUCLEOTIDE SEQUENCE CODING THEREFOR, EXPRESSION CONSTRUCTS AND VECTORS COMPRISING THESE SEQUENCES, MICROORGANISMS TRANSFORMED THEREWITH, PROCESSES FOR THE MICROBIOLOGICAL OXIDATION OF SAID ORGANIC COMPOUNDS AND IN PARTICULAR PROCESSES FOR THE PREPARATION OF INDIGO AND INDIRUBIN.

公开(公告)号：AU784049B2

公开(公告)日：2006-01-19

申请号：AU6439000

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12M1/40 ,  C12N9/00 ,  C12N1/21 ,  C12N9/02 ,  C12N15/09 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/42 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/11 ,  C12R1/19

Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.

公开(公告)号：BR0012772A

公开(公告)日：2002-04-02

申请号：BR0012772

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N15/70

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：NO20020350L

公开(公告)日：2002-01-23

申请号：NO20020350

申请日：2002-01-23

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12N1/21 ,  C12M1/40 ,  C12N9/02 ,  C12N15/09 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/42 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/11 ,  C12R1/19 ,  C12N

Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.

公开(公告)号：NO20020350D0

公开(公告)日：2002-01-23

申请号：NO20020350

申请日：2002-01-23

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN

IPC: C12N1/21 ,  C12M1/40 ,  C12N9/02 ,  C12N15/09 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/42 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/11 ,  C12R1/19 ,  C12N

Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.