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公开(公告)号：WO0107574A2
公开(公告)日：2001-02-01
申请号：PCT/EP0007252
申请日：2000-07-27
Applicant: BASF AG , HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING SHAN
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN
IPC: C12M1/40 , C12N1/21 , C12N9/02 , C12N15/09 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/11 , C12R1/19 , C12N9/00
CPC classification number: C12P7/6409 , C12N9/0071 , C12N9/0077 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P17/10 , C12P17/165 , C12Q1/26 , G01N2333/90245
Abstract: The invention relates to modified cytochrome P450 monooxygenases comprising a modified substrate profile, to nucleic acid sequences that code therefor, to expression constructs and vectors, and to recombinant microorganisms which contain these vectors. The invention also relates to methods for microbiologically producing terminally or subterminally hydroxylated aliphatic carboxylic acids.
Abstract translation: 本发明涉及具有改变的底物轮廓，编码核酸序列，表达构建体和载体，含有用于微生物生产终端或近hydroylierter脂族羧酸，这些载体和方法重组微生物修饰细胞色素P450单加氧酶。
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公开(公告)号：CA2378615C
公开(公告)日：2011-11-29
申请号：CA2378615
申请日：2000-07-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN
IPC: C12M1/40 , C12N15/53 , C12N1/21 , C12N9/02 , C12N15/09 , C12N15/70 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/11 , C12R1/19
Abstract: The invention relates to modified cytochrome P450 monooxygenases comprising a modified substrate profile, to nucleic acid sequences that code therefor, to expression constructs and vectors, and to recombinant microorganisms which contain these vectors. The invention also relates to methods for microbiologically producing terminally or subterminally hydroxylated aliphatic carboxylic acids.
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公开(公告)号：AU780694B2
公开(公告)日：2005-04-14
申请号：AU6830700
申请日：2000-07-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN , APPEL DANIEL
IPC: C12N15/09 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19 , C12N15/70
Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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公开(公告)号：NO20020380A
公开(公告)日：2002-03-22
申请号：NO20020380
申请日：2002-01-24
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANNEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF D , LI QING-SHAN , LUTZ-WAHL SABINE , APPEL DANIEL
IPC: C12N15/09 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19 , C12N
CPC classification number: C12N9/0071 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/6409 , C12P17/10 , C12P17/165 , C12Q1/26 , G01N2333/90245
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公开(公告)号：DE10014085A1
公开(公告)日：2001-09-27
申请号：DE10014085
申请日：2000-03-22
Applicant: BASF AG
Inventor： HAUER BERNHARD , LI QING-SHAN , SCHWANEBERG ULRICH , SCHMID ROLF , LUTZ-WAHL SABINE , APPEL DANIEL
IPC: C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P17/10 , C12P17/16 , C07H21/04 , C12N15/63 , C12N15/70 , C12P1/04 , C12P17/18
Abstract: Cytochrome P450 monooxygenase (I) that can oxidize at least one of the following types of substrates(A): (i) optionally substituted mono- or poly-cyclic aromatic heterocyclics containing nitrogen, sulfur or oxygen; (ii) optionally substituted mono- or poly-cyclic aromatics; (iii) linear or branched alkanes or alkenes, or (iv) optionally substituted cycloalkanes or cycloalkenes, is new.
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Patent Agency Ranking
公开(公告)号：AU6439000A
公开(公告)日：2001-02-13
申请号：AU6439000
申请日：2000-07-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN
IPC: C12M1/40 , C12N1/21 , C12N9/02 , C12N15/09 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/11 , C12R1/19 , C12N9/00
Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.
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公开(公告)号：CA2380186C
公开(公告)日：2012-03-13
申请号：CA2380186
申请日：2000-07-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN , LUTZ-WAHL SABINE , APPEL DANIEL
IPC: C12N15/09 , C12N15/53 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/70 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19
Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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公开(公告)号：NO20020380L
公开(公告)日：2002-03-22
申请号：NO20020380
申请日：2002-01-24
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANNEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF D , LI QING-SHAN , LUTZ-WAHL SABINE , APPEL DANIEL
IPC: C12N15/09 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19 , C12N
Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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公开(公告)号：NO20020380D0
公开(公告)日：2002-01-24
申请号：NO20020380
申请日：2002-01-24
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANNEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF D , LI QING-SHAN , LUTZ-WAHL SABINE , APPEL DANIEL
IPC: C12N15/09 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19 , C12N
Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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公开(公告)号：AU6830700A
公开(公告)日：2001-02-13
申请号：AU6830700
申请日：2000-07-27
Applicant: BASF AG
Inventor： HAUER BERNHARD , PLEISS JUERGEN , SCHWANEBERG ULRICH , SCHMITT JUTTA , FISCHER MARKUS , SCHMID ROLF , LI QING-SHAN
IPC: C12N15/09 , C12M1/40 , C12N1/21 , C12N9/02 , C12N15/53 , C12P7/02 , C12P7/04 , C12P7/22 , C12P7/64 , C12P17/10 , C12P17/16 , C12Q1/26 , C12R1/19 , C12N15/70
Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
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