公开(公告)号：DE19857127A1

公开(公告)日：2000-06-15

申请号：DE19857127

申请日：1998-12-11

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  WUENSCH THOMAS ,  WESTENFELDER HORST

IPC: A61K8/00 ,  A61K8/40 ,  A61Q17/00 ,  A61Q17/04 ,  C07C67/343 ,  C07C69/618 ,  C07C253/30 ,  C07C255/41 ,  C09K3/00 ,  C07C255/23 ,  C07F9/38 ,  C07C233/09 ,  C07C235/76 ,  A61K7/40

Abstract: New oligomeric 4,4-diarylbutadiene carboxylic acid ester or amide sunscreen compounds. Oligomeric 4,4-diarylbutadiene carboxylic acid esters or amides of formula (I) are new. R1, R2 = H; aliphatic-, cycloaliphatic-, aromatic- or araliphatic- group; or carboxylate, sulfonate or ammonium; R3 = aliphatic, cycloaliphatic, aromatic, araliphatic or heterocyclic group; carbonyl, sulfonyl, phosphonyl, carboxylic acid ester or CN; Y = O or N(R4); R4 = H or aliphatic-, cycloaliphatic-, aromatic-,araliphatic or heterocyclic group; m = 2-10; n = 1-3 X = the residue of a polyol with 2-10 OH groups (corresponding to m). Am Independent claim is included for preparation of (I).

公开(公告)号：CA2528311A1

公开(公告)日：2004-12-29

申请号：CA2528311

申请日：2004-06-08

Applicant: BASF AG

Inventor： WUENSCH THOMAS ,  HEIDENFELDER THOMAS ,  ANDRE VALERIE

IPC: A61K8/41 ,  A61K8/37 ,  A61K8/44 ,  A61Q5/00 ,  A61Q17/04

Abstract: The invention relates to a mixture consisting of an UV-A filter of formula ( I) and an UV-B filter of formula (II).

公开(公告)号：DE10044351A1

公开(公告)日：2002-03-21

申请号：DE10044351

申请日：2000-09-07

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  SCHEHLMANN VOLKER ,  WUENSCH THOMAS ,  DAUSCH WILMA M

IPC: A61K8/35 ,  A61K8/40 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q17/04 ,  A61K7/40 ,  A61K7/06

Abstract: Cosmetic or dermatological compositions comprising 0.1-10 wt.% of a cycloalkyl 3,3-diphenylacrylate (I) and 0.1-10 wt.% of a dibenzoylmethane derivative (II) are new. Cosmetic or dermatological compositions comprising 0.1-10 wt.% of a cycloalkyl 3,3-diphenylacrylate of formula (I) and 0.1-10 wt.% of a dibenzoylmethane derivative of formula (II) are new: R , R = H, 1-12C alkyl or 1-12C alkoxy; R = optionally substituted 3-10C cycloalkyl; R = H or CN; R -R = H or 1-4C alkyl; R , R = H, 1-12C alkyl or 1-12C alkoxy.

公开(公告)号：BR0102324A

公开(公告)日：2001-12-04

申请号：BR0102324

申请日：2001-03-15

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  HABECK THORSTEN ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/49 ,  A61K8/89 ,  A61K8/893 ,  A61K8/896 ,  A61K8/898 ,  A61K31/121 ,  A61K31/216 ,  A61K31/4184 ,  A61K31/4192 ,  A61K31/53 ,  A61K31/695 ,  A61K31/77 ,  A61K33/24 ,  A61K33/30 ,  A61P17/16 ,  A61Q1/04 ,  A61Q17/04 ,  C08L83/07 ,  A61K7/42

公开(公告)号：DE10012413A1

公开(公告)日：2001-09-20

申请号：DE10012413

申请日：2000-03-15

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  HABECK THORSTEN ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/49 ,  A61K8/89 ,  A61K8/893 ,  A61K8/896 ,  A61K8/898 ,  A61K31/121 ,  A61K31/216 ,  A61K31/4184 ,  A61K31/4192 ,  A61K31/53 ,  A61K31/695 ,  A61K31/77 ,  A61K33/24 ,  A61K33/30 ,  A61P17/16 ,  A61Q1/04 ,  A61Q17/04 ,  C08L83/07 ,  A61K7/40 ,  A61K7/42

公开(公告)号：DE19928033A1

公开(公告)日：2000-12-21

申请号：DE19928033

申请日：1999-06-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST

IPC: C07D233/64 ,  A61K8/00 ,  A61K8/02 ,  A61K8/06 ,  A61K8/49 ,  A61K47/22 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07D239/70 ,  C07D263/56 ,  C07D277/64 ,  A61K7/40

Abstract: Use of new and known bicyclic and tricyclic enamines as UV filters in cosmetic and pharmaceutical preparations is new. Also new is their use for the protection of plastics. Use of bicyclic and tricyclic enamines as UV filters in cosmetic and pharmaceutical preparations is new. R and R = CN; alkylcarbonyl; alkoxycarbonyl; aryloxycarbonyl; or optionally substituted aminocarbonyl; R = H; 1-20C alkyl; 3-20C cycloalkyl; or -CH2-CH2-SO3 M ; M = cation; X = -O-; -S-; or -N(R )-; Z' = group of formula (ii) or (iii): R = H; alkyl, cycloalkyl, alkoxy, cycloalkoxy, alkoxycarbonyl, alkyl-NH-CO-, (alkyl)2-NH-CO-, alkyl-NH- or (alkyl)2N- (each with up to 20C); CN; NH2; or SO3 M and more than 1 R can be present. Independent claims are also included for: (1) the use of compounds (I) as light screening agents for the protection of plastics; (2) (I; Z' = (iii); and (3) (I; Z' = (ii); R4 = R40; R1, R2 = R10, R20 respectively) R and R = CN or 2-10C alkoxycarbonyl optionally substituted with -(CH2)n-SO3 M ; R = H; CH3; or -(CH2)n-SO3 M ; R = H; 1-8C alkyl; 1-8C alkoxy; or -SO3 M ; n = 2 or 3; M = H or HN(R )(R )(R ) ; R -R = H lower alkyl optionally substituted with OH; or a metal cation; but at least one -(CH2)n-SO3 M or -SO3 M must be present.

公开(公告)号：DE19634229A1

公开(公告)日：1998-02-26

申请号：DE19634229

申请日：1996-08-23

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMUELLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/40 ,  C07D307/52 ,  C07D317/54 ,  C07D333/24 ,  A61K7/42

Abstract: The use of compounds of formula (I) as UV-A filters in cosmetic products (optionally in combination with standard UV absorbers) to protect the human skin against sunlight is claimed. R1-R3 = H or (cyclo)aliphatic group containing up to 18 C, or two of these groups can combine to form a 5 or 6-membered ring ; R4 = optionally substituted (hetero)aryl containing 5-12 ring atoms ; and R5 = R4 or H. Also claimed are (i) cosmetic products containing (I) for protecting the epidermis layer against UV radiation with a wavelength of 280-400 nm and (ii) compounds of formula (II) : R7-R9 = lower alkyl ; R6 = 2-thienyl (optionally substituted with lower alkyl), 4-(3,5-di-t-butyl)-1-hydroxyphenyl or 4-(3,5-di-t-butyl)-1-alkoxyphenyl.

公开(公告)号：SI1046391T1

公开(公告)日：2005-04-30

申请号：SI200030535

申请日：2000-03-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.

公开(公告)号：DE50104819D1

公开(公告)日：2005-01-20

申请号：DE50104819

申请日：2001-09-20

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  MATHAUER KLEMENS ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  ICHIHARA HIDEYUKI ,  IKEDA TAKAHIRO ,  DAUSCH WILMA M

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/81 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/10 ,  A61Q17/04 ,  C08F2/22 ,  C08F2/24 ,  C08F2/44 ,  C08K5/00 ,  C08L57/00 ,  A61K7/00

Abstract: Colorant-containing aqueous polymer dispersions comprise (all amounts by wt. of polymer matrix): (A) (i) a polymer matrix based on an ethylenically-unsaturated monomer (M); and (ii) an organic colorant comprising a dye or pigment, UV-absorber or optical brightener uniformly dispersed in the polymer matrix (0.5-50%); (B) a nonionic surfactant (0.1-20%); and (C) an amphiphilic polymer with 0.5-10 mol./kg anionic-functional groups (1-50%). An Independent claim is also included for preparation of the dispersions by: (i) dissolving the colorant in monomer M, (ii) emulsifying the mixture to give a conventional oil-in-water emulsion, (iii) homogenizing to give a mini-emulsion with monomer droplets of average diameter below 1,000 nm and then (iv) polymerizing the mini-emulsion in presence of a soluble free-radical initiator together with (B) (0.1-20 wt.%) and (C) (1-50 wt.%), each wt. being based on the wt. of M.

公开(公告)号：DE50007725D1

公开(公告)日：2004-10-21

申请号：DE50007725

申请日：2000-03-18

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.