公开(公告)号：CL2018002341A1

公开(公告)日：2018-09-14

申请号：CL2018002341

申请日：2018-08-16

Applicant: BASF SE

Inventor： POP CRISTINA ,  HUSTON DAVENPORT ADRIENNE ,  LISZKA MICHAEL ,  TAN XUQIU ,  KUTSCHER JOCHEN ,  FUNKE ANDREAS ,  HAEFNER STEFAN ,  SEITTER MICHAEL FRIEDRICH HERMANN

IPC: A21D10/02 ,  A21D8/02

Abstract: ENZIMAS DE LIPASA Y MÉTODOS PARA USAR LAS LIPASAS EN EL HORNEADO PARA MEJORAR EL VOLUMEN, LA ESTABILIDAD, LA TOLERANCIA DE UN PRODUCTO HORNEADO Y/O PARA REDUCIR Y REDUCIR O ELIMINAR EL USO DE DATEM.

公开(公告)号：AU2017221289A1

公开(公告)日：2018-08-30

申请号：AU2017221289

申请日：2017-02-15

Applicant: BASF SE

Inventor： POP CRISTINA ,  HUSTON DAVENPORT ADRIENNE ,  LISZKA MICHAEL ,  TAN XUQIU ,  KUTSCHER JOCHEN ,  FUNKE ANDREAS ,  HAEFNER STEFAN ,  SEITTER MICHAEL FRIEDRICH HERMANN

IPC: A21D8/02 ,  A21D10/02

Abstract: Lipase enzymes and methods of using the lipases in a baking for improving the volume, stability, tolerance of a baked product and/or reducing and reducing or eliminating the use of DATEM.

公开(公告)号：CA3004990A1

公开(公告)日：2017-06-08

申请号：CA3004990

申请日：2016-12-02

Applicant: BASF SE

Inventor： HAEFNER STEFAN ,  THYWISSEN ANDREAS ,  HARTMANN HOLGER ,  BOEHMER NICO

IPC: C12N1/14 ,  C12P21/02

Abstract: The present invention relates to a method of producing a recombinant polypeptide a filamentous fungus which is genetically modified to decrease or eliminate the activity of cellulase regulator 2 (CLR2) and to express said recombinant polypeptide. The method further relates to a filamentous fungus Myceliophthora thermophila, which is genetically modified to decrease or eliminate the activity of CLR2 and the use of this filamentous fungus in the production of a recombinant polypeptide.

公开(公告)号：CY1114595T1

公开(公告)日：2016-10-05

申请号：CY131100999

申请日：2013-11-11

Applicant: BASF SE

Inventor： KRÖGER BURKHARD ,  ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  SCHRÖDER HARTWIG ,  HAEFNER STEFAN

IPC: C12N15/77 ,  C07K14/34 ,  C12P13/08

Abstract: Ηπαρούσαεφεύρεσηαφοράστηχρησιμοποίησηακολουθιώννουκλεϊνικούοξέοςγιατηρύθμισητηςμεταγραφήςκαιέκφρασηςγονιδίων, στουςνέουςίδιουςπροαγωγούςκαιενότητεςέκφρασης, σεμεθόδουςγιατηντροποποίησηή πρόκλησητουρυθμούμεταγραφήςκαι/ήτουρυθμούέκφρασηςγονιδίων, σεκασέτεςέκφρασηςπουπεριέχουντιςενότητεςέκφρασης, στουςγενετικάτροποποιημένουςμικροοργανισμούςμετροποποιημένοή προκληθένταρυθμόμεταγραφήςκαι/ήρυθμόέκφρασης, καθώςκαισεμεθόδουςγιατηνπαρασκευήβιοσυνθετικώνπροϊόντωνμεκαλλιέργειατωνγενετικάτροποποιημένωνμικροοργανισμών.

公开(公告)号：BRPI1008267A2

公开(公告)日：2015-08-25

申请号：BRPI1008267

申请日：2010-02-12

Applicant: BASF SE

Inventor： SCHRÖDER HARTWIG ,  HAEFNER STEFAN ,  ABENDROTH GREGORY VON ,  HOLLMANN RAJAN ,  RADDATZ ALINE ,  ERNST HANSGEORG ,  GURSKI HANS

IPC: C12N1/32 ,  C12P7/46 ,  C12P17/10 ,  C12R1/01

公开(公告)号：BRPI0815409A2

公开(公告)日：2014-10-21

申请号：BRPI0815409

申请日：2008-08-14

Applicant: BASF SE

Inventor： SCHOLTEN EDZARD ,  DAEGELE DIRK ,  HAEFNER STEFAN ,  SCHROEDER HARTWIG

IPC: C12N1/20 ,  C12P7/46 ,  C12P17/10

Abstract: The present invention relates to a novel bacterial strain designated DD1, which has the ability to produce organic acids, in particular succinic acid (SA), which was originally isolated from bovine rumen, and is capable of utilizing glycerol as a carbon source; and variant strains derived there from retaining said capability; as well as to methods of producing organic acids, in particular succinic acid by making use of said microorganism.

公开(公告)号：CA2875603A1

公开(公告)日：2014-01-09

申请号：CA2875603

申请日：2013-07-03

Applicant: WINTERSHALL HOLDING GMBH ,  BASF SE

Inventor： BROCKMANN BEATA ,  HEROLD ANDREA ,  ZELDER OSKAR ,  HAEFNER STEFAN ,  FLECK CHRISTIAN ,  SCHRODER HARTWIG ,  GRANSTROM MARI ,  SCHMIDT JULIA KRISTIANE

IPC: C12N9/10 ,  C12P19/04

Abstract: The present invention relates to genetically modified microorganisms capable of producing beta-glucans, characterized in that said genetically modified microorganism overexpresses (i) a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity, and/or (ii) a polypeptide having 1,3-ß-glucan synthase-activity, compared to a corresponding non-modified control microorganism of the same strain. The present invention also relates to the use of a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity or the use of such a polypeptide for producing ß-glucans. Furthermore, the present invention relates to methods for producing ß-glucans comprising the introduction of a promoter upstream of a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity thereby increasing the expression of said polynucleotide, or a polynucleotide encoding a polypeptide having 1,3-ß-D-glucan synthase-activity into a microorganism being able to synthesize ß-glucans.

公开(公告)号：ES2380000T3

公开(公告)日：2012-05-07

申请号：ES07123772

申请日：2005-12-21

Applicant: BASF SE

Inventor： HAEFNER STEFAN ,  SCHROEDER HARTWIG ,  ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  HEROLD ANDREA

IPC: C12N15/77 ,  C07K14/34

Abstract: Bacteria corineforme genéticamente modificada, transformada con al menos un vector que contiene al menos un casete de expresión, en cuyo caso el casete de expresión comprende en dirección 5' -3' un módulo de secuencia de la siguiente fórmula general II: 5' -P1-(-Ax-Px-)n-Ay-Py-G-3' (II) Donde n representa un valor de número entero de 0 a 10, Ax y Ay son iguales o diferentes y representan un enlace químico o una secuencia de ácido nucleico enlazante; P1, Px y Py codifican secuencias de promotores iguales o diferentes derivadas de bacterias corineformes iguales o diferentes, que comprenden al menos un segmento que enlaza polimerasa de ARN; y al menos Py comprende un segmento de secuencia terminal 3' que facilita el enlace ribosómico, G representa al menos una secuencia de ácido nucleico codificante que está enlazada funcionalmente con la secuencia regulatoria ubicada corriente arriba de 5'.

公开(公告)号：PL1942198T3

公开(公告)日：2012-04-30

申请号：PL07123761

申请日：2005-07-16

Applicant: BASF SE

Inventor： ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  KRÖGER BURKHARD ,  SCHRÖDER HARTWIG ,  HAEFNER STEFAN

IPC: C12Q1/68 ,  C07K14/34

公开(公告)号：AT531819T

公开(公告)日：2011-11-15

申请号：AT07123761

申请日：2005-07-16

Applicant: BASF SE

Inventor： ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  KROEGER BURKHARD ,  SCHROEDER HARTWIG ,  HAEFNER STEFAN

IPC: C12Q1/68 ,  C07K14/34

Abstract: A specific nucleic acid (I) with promoter activity is used for transcribing genes, where (I) is: (a) a sequence (1) of 178 nucleotides (reproduced); (b) a derivative of (1) with >= 90% identity, formed by substitution, insertion or deletion; (c) a sequence that hybridizes to (1) under stringent conditions; or (d) a functional fragment of (a)-(c). Independent claims are also included for: (1) use of an expression unit (EU), containing and linked to a nucleic acid (NA) that ensures translation of RNA, for expressing genes; (2) (I), except sequence (1) itself, as new compounds and EU containing it; (3) method for altering (or causing) the transcription (or expression) rate of genes in microorganisms relative to the wild type; (4) expression cassette (EC) comprising EU, at least one other functionally linked NA to be expressed and optionally other genetic control elements that are heterologous with respect to EU; (5) expression vector containing EC; (6) genetically modified microorganism (GMM) in which the transcription rate of at least one gene is altered (or caused) relative to the wild type; (7) GMM containing EU and a functionally linked gene to be expressed, where this is heterologous with respect to EU; (8) preparation of biosynthetic products (A) by culturing the GMM of (6) or (7); (9) use of the sequence aggagga (21) as ribosome-binding site in expression units for expressing genes in Corynebacterium or Brevibacterium; (10) use of the sequences ttaatt (19) or taagct (20) as -10 regions in EU for expressing genes in Corynebacterium or Brevibacterium; and (11) EU that contain (21) or at least one of (19) or (20).