公开(公告)号：AU2003299683A1

公开(公告)日：2004-07-22

申请号：AU2003299683

申请日：2003-12-18

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.