公开(公告)号：WO2008157748A2

公开(公告)日：2008-12-24

申请号：PCT/US2008067616

申请日：2008-06-20

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  CHOO CAROLYN ,  FAICT DIRK ,  RODRIGUEZ ALFREDO

Inventor： CHOO CAROLYN ,  FAICT DIRK ,  RODRIGUEZ ALFREDO

IPC: A61L2/00 ,  A61L2/02 ,  A61L2/04 ,  B65B55/02

CPC classification number: A61L2/0011 ,  A61L2/0023 ,  A61L2/02 ,  A61L2/04 ,  B65B55/02

Abstract: The present disclosure provides a sterilized medical system that includes an ultra high pressure sterilized glucose solution in a container. The sterile glucose solution may contain less than about 40 ppm total glucose degradation product. The glucose solution may be a ready-to-use infusion solution disposed in a single chamber container.

Abstract translation: 本公开提供了一种在容器中包括超高压灭菌葡萄糖溶液的灭菌医疗系统。 无菌葡萄糖溶液可含有小于约40ppm的总葡萄糖降解产物。 葡萄糖溶液可以是设置在单室容器中的即用型输注溶液。

公开(公告)号：BR0317450A

公开(公告)日：2005-11-16

申请号：BR0317450

申请日：2003-12-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

公开(公告)号：MX2009014111A

公开(公告)日：2010-03-09

申请号：MX2009014111

申请日：2008-06-20

Applicant: BAXTER INT

Inventor： CHOO CAROLYN ,  RODRIGUEZ ALFREDO ,  FAICT DIRK

IPC: A61L2/00 ,  A61L2/02 ,  A61L2/04 ,  B65B55/02

Abstract: La presente invención proporciona un sistema médico esterilizado que incluye una solución de glucosa esterilizada a alta presión en un contenedor o recipiente. La solución de glucosa estéril puede contener menos de aproximadamente 40 ppm del producto de degradación de glucosa total. La solución de glucosa puede ser una solución de infusión lista para usarse dispuesta en un contenedor de de cámara individual.

公开(公告)号：CA2510788A1

公开(公告)日：2004-07-15

申请号：CA2510788

申请日：2003-12-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： CHOO CAROLYN ,  ZIESKE PAUL ,  MARTIS LEO

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Glucose polymer-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The glucose polymer-based solution preferably includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the glucose polymer-based solution to be mixed prior to infusion into a patient. The glucose polymer-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

公开(公告)号：HK1088535A1

公开(公告)日：2006-11-10

申请号：HK06108881

申请日：2006-08-10

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K20060101 ,  A61K31/718 ,  A61K31/724 ,  A61M20060101 ,  A61M1/28

Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

公开(公告)号：AU2003299683A1

公开(公告)日：2004-07-22

申请号：AU2003299683

申请日：2003-12-18

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

公开(公告)号：ES2755946T3

公开(公告)日：2020-04-24

申请号：ES03799967

申请日：2003-12-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Un recipiente de múltiples cámaras que aloja una solución de diálisis peritoneal de dos partes en el que la primera parte se almacena en una primera cámara del recipiente de múltiples cámaras y en el que la primera parte consiste en una primera solución que contiene icodextrina que varía de aproximadamente 100,0 g/l a aproximadamente 220,0 g/l, en el que la primera parte tiene un pH que varía de aproximadamente 1,5 a aproximadamente 5,0; y en el que la segunda parte se almacena en una segunda cámara del recipiente de múltiples cámaras y en el que la segunda parte comprende una solución tampón que tiene un pH que varía de aproximadamente 7,0 a aproximadamente 12; y en el que la solución tampón no contiene aminoácidos con un pK1 de entre 7 y 13, tales como glicina, alanina e histidina; y en el que la primera parte y la segunda parte están formadas y dispuestas de modo que la primera parte y la segunda parte se mezclen antes de su infusión a un paciente.

公开(公告)号：SG169228A1

公开(公告)日：2011-03-30

申请号：SG2006072987

申请日：2003-12-18

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： MARTIS LEO ,  CHOO CAROLYN ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Glucose polymer-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The glucose polymer-based solution preferably includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the glucose polymer based-solution to be mixed prior to infusion into a patient. The glucose polymer-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.

公开(公告)号：AU2003299683B2

公开(公告)日：2008-10-02

申请号：AU2003299683

申请日：2003-12-18

Applicant: BAXTER HEALTHCARE SA ,  BAXTER INT

Inventor： CHOO CAROLYN ,  MARTIS LEO ,  ZIESKE PAUL

IPC: A61K31/718 ,  A61K31/724 ,  A61M1/28

Abstract: Icodextrin-based solutions and methods of making same that can be used during medical therapy, such as dialysis therapy are provided. The icodextrin-based solution at least includes a first solution containing icodextrin at a pH ranging from about 1.5 to about 5.0 and a buffer solution at a pH ranging from about 7.0 to about 12.0 that are so constructed and arranged allowing the icodextrin-based solution to be mixed prior to infusion into a patient. The icodextrin-based solutions of the present invention can be made at physiologic pH and with minimal glucose degradation products.