公开(公告)号：NO793417L

公开(公告)日：1980-04-29

申请号：NO793417

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： COLLINS HENRY W ,  MEASELLS PAUL E ,  GAJEWSKI HENRY M ,  MIRIPOL JEFFREY E ,  GEISSLER ULRICH C ,  STITH WILLIAM J ,  GRODE GERALD A ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M1/36 ,  A61M5/14 ,  C08K5/12 ,  A61M

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：IT8019600D0

公开(公告)日：1980-01-31

申请号：IT1960080

申请日：1980-01-31

Applicant: BAXTER TRAVENOL LAB

Inventor： BUCKLES RICHARD G ,  GARBER JAN W ,  GEISSLER ULRCH C ,  GRODE GERALD A ,  STITH WILLIAM J ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M5/14 ,  C08K5/12 ,  A61B

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable ester such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：FR2471928B1

公开(公告)日：1986-01-17

申请号：FR8006333

申请日：1980-03-21

Applicant: BAXTER TRAVENOL LAB

Inventor： BUCKLES RICHARD G ,  GARBER JAN W ,  GEISSLER ULRICH C ,  GRODE GERALD A ,  STITH WILLIAM J ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M5/14 ,  C08K5/12 ,  B65D81/24 ,  A61M1/00

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable ester such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：CA1140287A

公开(公告)日：1983-01-25

申请号：CA338467

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： GEISSLER ULRICH C ,  GRODE GERALD A ,  STITH WILLIAM J ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M1/36 ,  A61M5/14 ,  C08K5/12

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexyl-phthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：ZA81258B

公开(公告)日：1982-02-24

申请号：ZA81258

申请日：1981-01-15

Applicant: BAXTER TRAVENOL LAB

Inventor： GRODE GERALD A ,  MIRIPOL JEFFREY E

IPC: A01N1/02 ,  A61K35/14 ,  C07D ,  C12M

Abstract: An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.

公开(公告)号：ZA8100258B

公开(公告)日：1982-02-24

申请号：ZA8100258

申请日：1981-01-15

Applicant: BAXTER TRAVENOL LAB

Inventor： GRODE GERALD A ,  MIRIPOL JEFFREY E

IPC: A01N1/02 ,  A61K35/14 ,  C07D ,  C12M

CPC classification number: A01N1/02 ,  A01N1/0226

公开(公告)号：DE2943179A1

公开(公告)日：1980-05-08

申请号：DE2943179

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： COLLINS HENRY W ,  GAJEWSKI HENRY M ,  GEISSLER ULRICH C ,  GRODE GERALD A ,  MEASELLS PAUL E ,  MIRIPOL JEFFREY E ,  STITH WILLIAM J ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M1/36 ,  A61M5/14 ,  C08K5/12 ,  A61M5/00

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：IT7926788D0

公开(公告)日：1979-10-25

申请号：IT2678879

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： HENRY COLLINS W ,  GAJEWSKI HENRY M ,  GEISSLER ULRICH C ,  GRODE GERALD A ,  MEASELLS PAUL E ,  MIRIPOL JEFFREY E ,  WILLIAM STITH J ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M1/36 ,  A61M5/14 ,  C08K5/12 ,  C08L

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

公开(公告)号：IT7922961V0

公开(公告)日：1979-10-25

申请号：IT2296179

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： COLLINS HENRY W ,  GAJEWSKI HENRY M ,  GEISSLER ULRICH C ,  GRODE GERALD A

IPC: A61J1/10 ,  A61J1/00 ,  A61J1/05 ,  A61L29/00 ,  A61L31/00 ,  A61M1/36 ,  A61M5/00 ,  C08K5/12

Abstract: A blood bag or other container which is made of a flexible, hemocompatible, sterilizable plastic material free of blood-extractable plasticizer. The blood bag contains an insert member which comprises a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates. Such a blood bag is capable of reducing the plasma hemoglobin in stored blood, when compared with similar blood bags without the insert member.