公开(公告)号：US4140162A

公开(公告)日：1979-02-20

申请号：US81992477

申请日：1977-07-28

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  MEASELLS PAUL E ,  LAURIN DEAN G ,  CZUBA LEONARD F

IPC: C08L23/00 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  C08L7/00 ,  C08L21/00 ,  C08L23/04 ,  C08L23/10 ,  C08L51/00 ,  C08L51/02 ,  C08L53/00 ,  C08L77/00 ,  C08L101/00 ,  B65D37/00

CPC classification number: A61J1/10 ,  Y10T428/1345

Abstract: A clear, autoclavable, blow-moldable plastic formulation for medical and other uses comprises a two, or optionally three, component system including (1) a polyolefin consisting of propylene units as a first component, (2) a block copolymer having thermoplastic rubber characteristics with a central block of ethylenebutylene copolymer and terminal blocks of polystyrene, and (3) an optional third ingredient comprising a softening agent of polyethylene or poly(ethylene-vinyl acetate), which is particularly desirably used if the thermoplastic rubber copolymer has a molecular weight of more than 70,000. The formulation is essentially free of liquid plasticizers.

Abstract translation: 用于医疗和其它用途的透明的，可高压灭菌的可吹塑塑料制剂包括两种或任选的三种组分体系，包括（1）由作为第一组分的丙烯单元组成的聚烯烃，（2）具有热塑性橡胶特性的嵌段共聚物 具有乙烯丁烯共聚物的中心嵌段和聚苯乙烯的端基，和（3）包含聚乙烯或聚（乙烯 - 乙酸乙烯酯）的软化剂的任选的第三成分，如果热塑性橡胶共聚物具有分子量 超过70,000。 该制剂基本上不含液体增塑剂。

公开(公告)号：EP0120873A4

公开(公告)日：1986-11-26

申请号：EP83902616

申请日：1983-07-21

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  MEASELLS PAUL

IPC: A61M1/00 ,  A61J1/10 ,  A61L31/14 ,  A61L33/00 ,  A61J1/00

CPC classification number: A61L31/143 ,  A61L31/141 ,  C08K5/09 ,  C08K5/12 ,  Y10S128/24 ,  A61L31/048 ,  C08L27/06

Abstract: A method of storing blood components uses a blood component storage container which is made of a plasticized polyvinyl chloride formulation which includes a heat stabilizer system selected from the group consisting of salts of C10 to C26 saturated fatty acids present in an amount of less than about one percent by weight of the composition. Surprisingly, use of only minimal amounts of these higher molecular weight fatty acids results in an effectively heat stabilized product suited for mass production techniques. As a result, the total amount of the heat stabilizer which can possibly leach into blood plasma is significantly reduced. The material from which the container is made preferably includes an effective amount of a plasticizer which is also essentially nonextractable in blood plasma.

公开(公告)号：AU535149B2

公开(公告)日：1984-03-08

申请号：AU4731879

申请日：1979-05-23

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  LAURIN DEAN G ,  MEASELLS PAUL ,  WEBSTER R DANIEL

IPC: A61J1/00 ,  A61J1/05 ,  B32B27/08 ,  B32B27/28 ,  B32B27/32 ,  B65D65/40 ,  C08L23/02 ,  C09D153/00 ,  B32B1/02 ,  B32B7/02 ,  B32B25/14 ,  B32B27/30

Abstract: A multiple-layered, autoclavable, flexible plastic sheet comprises (a) at least one first layer consisting essentially of 30 to 90 percent by weight of a block copolymer having thermoplastic rubbery characteristics and having rubbery olefin blocks and blocks of a polystyrene; and from 10 to 70 percent by weight of a polyolefin derived principally from at least one of propylene, ethylene and 4-methylpentene-1, said polyolefin having a Vicat Softening Temperature of about 120 DEG C.; and (b) at least one second layer consisting essentially of a polyolefin derived principally by from at least one of propylene, ethylene, and 4-methylpentene-1 and being of semi-crystalline characteristics to exhibit low permeability to water vapor, the first and second layers being bonded together in alternating arrangement.

公开(公告)号：CA1155578A

公开(公告)日：1983-10-18

申请号：CA316346

申请日：1978-11-16

Applicant: BAXTER TRAVENOL LAB

Inventor： BECKER LAWRENCE F ,  DONOHUE JOHN J ,  LAURIN DEAN G ,  GAJEWSKI HENRY M

IPC: A61L29/04 ,  A61L29/14 ,  A61M25/00 ,  C08L53/00

Abstract: IMPROVED BALLOON-TYPE CATHETER Inventors: Lawrence F. Becker John J. Donohue Dean G. Laurin Henry M. Gajewski A balloon-type catheter is disclosed having a catheter shank made of a block copolymer having thermoplastic rubber characteristics with a central block of ethylene-butylene copolymer and terminal blocks of polystyrene. The inflatable balloon member, and preferably the distal Y-member, of the catheter are made of an elastic composition which includes the same or a similar block copolymer, in the presence of polystyrene or equivalent material as a tackifying agent, polypropylene, and an oil-type plasticizer.

公开(公告)号：CA1126637A

公开(公告)日：1982-06-29

申请号：CA326223

申请日：1979-04-24

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  LAURIN DEAN G ,  MEASELLS PAUL ,  WEBSTER R DANIEL

IPC: A61J1/00 ,  A61J1/05 ,  B32B27/08 ,  B32B27/28 ,  B32B27/32 ,  B65D65/40 ,  C08L23/02 ,  C09D153/00 ,  B65D30/02

Abstract: A multiple-layered, autoclavable, flexible plastic sheet comprises (a) at least one first layer consisting essentially of 30 to 90 percent by weight of a block copolymer having thermoplastic rubbery characteristics and having rubbery olefin blocks and blocks of a polystyrene; and from 10 to 70 percent by weight of a polyolefin derived principally from at least one of propylene, ethylene and 4-methylpentene-1, said polyolefin having a Vicat Softening Temperature of about 120.degree.C.; and (b) at least one second layer consisting essentially of a polyolefin derived principally from at least one of propylene, ethylene, and 4-methylpentene-1 and being of semicrystalline characteristics to exhibit low permeability to water vapor, the first and second layers being bonded together in alternating arrangement.

公开(公告)号：NO792012A

公开(公告)日：1979-12-20

申请号：NO792012

申请日：1979-06-18

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  LAURIN DEAN G ,  MEASELLS PAUL ,  WEBSTER R DANIEL

IPC: A61J1/00 ,  A61J1/05 ,  B32B27/08 ,  B32B27/28 ,  B32B27/32 ,  B65D65/40 ,  C08L23/02 ,  C09D153/00 ,  B29D

CPC classification number: B32B27/08 ,  A61J1/10 ,  B32B27/302 ,  B32B27/32 ,  B32B2250/246 ,  B32B2250/42 ,  B32B2307/7246 ,  B32B2323/04 ,  B32B2325/00 ,  B32B2439/00 ,  B32B2439/06 ,  C08L23/02 ,  C09D153/00 ,  Y10T428/1334 ,  Y10T428/24967 ,  Y10T428/26 ,  Y10T428/31913 ,  C08L53/00 ,  C08L2666/24

公开(公告)号：AU4148478A

公开(公告)日：1979-05-31

申请号：AU4148478

申请日：1978-11-10

Applicant: BAXTER TRAVENOL LAB

Inventor： BECKER LAWRENCE F ,  DONOHUE JOHN J ,  LAURIN DEAN G ,  GAJEWSKI HENRY M

IPC: A61L29/04 ,  A61L29/14 ,  A61M25/00 ,  C08J5/00 ,  C08K3/22 ,  C08K5/20 ,  C08L53/00

公开(公告)号：DE2848854A1

公开(公告)日：1979-05-23

申请号：DE2848854

申请日：1978-11-10

Applicant: BAXTER TRAVENOL LAB

Inventor： BECKER LAWRENCE F ,  DONOHUE JOHN J ,  LAURIN DEAN G ,  GAJEWSKI HENRY M

IPC: A61L29/04 ,  A61L29/14 ,  A61M25/00 ,  C08L53/00

公开(公告)号：DE2831034A1

公开(公告)日：1979-02-08

申请号：DE2831034

申请日：1978-07-14

Applicant: BAXTER TRAVENOL LAB

Inventor： GAJEWSKI HENRY M ,  MEASELLS PAUL E ,  LAURIN DEAN G ,  CZUBA LEONARD F

IPC: C08L23/00 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  C08L7/00 ,  C08L21/00 ,  C08L23/04 ,  C08L23/10 ,  C08L51/00 ,  C08L51/02 ,  C08L53/00 ,  C08L77/00 ,  C08L101/00 ,  C08L23/08 ,  C08L31/04

Abstract: A clear, autoclavable, blow-moldable plastic formulation for medical and other uses comprises a two, or optionally three, component system including (1) a polyolefin consisting of propylene units as a first component, (2) a block copolymer having thermoplastic rubber characteristics with a central block of ethylenebutylene copolymer and terminal blocks of polystyrene, and (3) an optional third ingredient comprising a softening agent of polyethylene or poly(ethylene-vinyl acetate), which is particularly desirably used if the thermoplastic rubber copolymer has a molecular weight of more than 70,000. The formulation is essentially free of liquid plasticizers.

公开(公告)号：IT1166913B

公开(公告)日：1987-05-06

申请号：IT2678879

申请日：1979-10-25

Applicant: BAXTER TRAVENOL LAB

Inventor： COLLINS W HENRY ,  GAJEWSKI HENRY M ,  GEISSLER ULRICH C ,  GRODE GERALD A ,  MEASELLS PAUL E ,  MIRIPOL JEFFREY E ,  STITH J WILLIAM ,  WILLIAMS RONALD A

IPC: A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61L33/00 ,  A61M1/36 ,  A61M5/14 ,  C08K5/12 ,  C08L

Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.