Abstract:
A system (10) which embodies the features of the invention includes first means (12) for establishing a flow of whole blood from a donor and second means (14) for separating the whole blood into essentially plasma and plasma-poor components without using a centrifugation device. The system (10) also includes third means (16) for collecting a volume of the separated plasma and forth means (18) for returning the plasma-poor components associated with this collected volume of separated plasma to the donor. The system further includes fifth means (20) for collecting a volume of whole blood. In the preferred embodiment, the second means (14) includes microporous membrane means (22) which is operative for filtering the plasma from the other components of whole blood. Also in the preferred embodiment, the fifth means (20) includes means (60) for collecting the components of the whole blood in response to subsequent centrifugal separation.
Abstract:
Separable integral donor connector (15) with an improved clamping mechanism for use with flexible blood collection tubing (16). The device is positioned in line with the blood tubing (16) between a phlebotomy needle and the collection bag (10). Separation of the device is accomplished by manipulation and breaking of a thin frangible ring area (26) and drawing the sections (18 and 24) of the device apart. This separation exposes an internally-mounted needle (36) that may be used for penetration of sample collection tube closures and subsequent collection of blood samples. The present embodiment of this invention includes improved manually-operated clamping means that are flexibly biased away from the blood tubing. Clamping jaws (28 and 30) of differing lengths are disclosed which, when engaged, overlap and cause an area of tubing to be collapsed into a distinctive, S-shaped configuration which crimps and more effectively seals the tubing against blood flow. The clamping device is free from restraints permitting simple, one-handed operation, as well as the broadest control over the blood flow.
Abstract:
PLASMAPHERESIS ASSEMBLY AND ASSOCIATED FLUID MANIFOLD A plasmapheresis assembly includes a fluid manifold which interconnects the phlebotomy needle of the assembly with a pair of blood collection containers. The manifold includes a removably insertable plug member which when inserted, blocks fluid flow through the manifold to retain anticoagulant solution in the containers prior to use and which, after removal, affords fluid flow through the manifold and permits the attachment of a recipient set to the manifold.
Abstract:
Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable ester such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.
Abstract:
Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.