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公开(公告)号：EP0044864A4
公开(公告)日：1982-06-10
申请号：EP81900589
申请日：1980-12-29
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
CPC classification number: A01N1/02 , A01N1/0226
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公开(公告)号：CA1341221C
公开(公告)日：2001-05-01
申请号：CA545136
申请日：1987-08-24
Applicant: BAXTER TRAVENOL LAB
Inventor： GLASH DEAN , MIRIPOL JEFFREY E , FOLEY JOHN , BILSTAD ARNOLD
Abstract: A thin film of white blood cells is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 15 milliwatts per square cm.. At such a radiation intensity it is not necessary to agitate the thin film of white blood cells to accomplish the purposes of this invention. The white blood cells so processed substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation.
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公开(公告)号：NO793417A
公开(公告)日：1980-04-29
申请号：NO793417
申请日：1979-10-25
Applicant: BAXTER TRAVENOL LAB
Inventor： COLLINS HENRY W , MEASELLS PAUL E , GAJEWSKI HENRY M , MIRIPOL JEFFREY E , GEISSLER ULRICH C , STITH WILLIAM J , GRODE GERALD A , WILLIAMS RONALD A
CPC classification number: A61J1/10 , A61L33/0005 , A61L33/0052 , A61M1/3687 , C08K5/12 , Y10S128/24 , C08L67/02
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公开(公告)号：FI793324A
公开(公告)日：1980-04-27
申请号：FI793324
申请日：1979-10-25
Applicant: BAXTER TRAVENOL LAB
Inventor： COLLINS HENRY W , MEASELLS PAUL E , GAJEWSKI HENRY M , MIRIPOL JEFFREY E , GEISSLER ULRICH C , STITH WILLIAM J , GRODE GERALD A , WILLIAMS RONALD A
Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.
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公开(公告)号：IT1135257B
公开(公告)日：1986-08-20
申请号：IT1945381
申请日：1981-02-02
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
Abstract: An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.
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Patent Agency Ranking
公开(公告)号：DE3070750D1
公开(公告)日：1985-07-11
申请号：DE3070750
申请日：1980-12-29
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
Abstract: An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.
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公开(公告)号：CA1140860A
公开(公告)日：1983-02-08
申请号：CA370056
申请日：1981-02-04
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
Abstract: RED CELL STORAGE SOLUTION Inventors: Gerald A. Grode Jeffrey E. Miripol An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.
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公开(公告)号：ZA81258B
公开(公告)日：1982-02-24
申请号：ZA81258
申请日：1981-01-15
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
Abstract: An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.
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公开(公告)号：ZA8100258B
公开(公告)日：1982-02-24
申请号：ZA8100258
申请日：1981-01-15
Applicant: BAXTER TRAVENOL LAB
Inventor： GRODE GERALD A , MIRIPOL JEFFREY E
CPC classification number: A01N1/02 , A01N1/0226
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公开(公告)号：DE2943179A1
公开(公告)日：1980-05-08
申请号：DE2943179
申请日：1979-10-25
Applicant: BAXTER TRAVENOL LAB
Inventor： COLLINS HENRY W , GAJEWSKI HENRY M , GEISSLER ULRICH C , GRODE GERALD A , MEASELLS PAUL E , MIRIPOL JEFFREY E , STITH WILLIAM J , WILLIAMS RONALD A
IPC: A61J1/00 , A61J1/05 , A61J1/10 , A61K35/14 , A61L33/00 , A61M1/36 , A61M5/14 , C08K5/12 , A61M5/00
Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexylphthalate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.
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