公开(公告)号：AU5140601A

公开(公告)日：2001-11-07

申请号：AU5140601

申请日：2001-04-06

Applicant: BIO RAD LABORATORIES

Inventor： PEREZ EVELIO

IPC: B01D57/02 ,  B03C5/00 ,  G01N27/447

Abstract: Parallel plate slab gel enclosures (slab gel cassettes) used for vertical slab gel electrophoresis are secured to a frame to form a chamber for an upper buffer solution, and the securement is achieved by a pair of clamps that compress the cassettes against the frame. The clamps are preferably mounted to the frame in a pivotal connection that enables the user to easily rotate the clamps in and out of their clamping positions. An additional preferred feature is a pin protruding from each clamp in a position causing the pint to move upward against the bottom of the cassette and push the cassette upwards as the clamp is being engaged. This is particularly useful for cassettes formed of plates of unequal height where the shorter plate fits under an inverse shoulder on a gasket which thereby seals against both plates.

公开(公告)号：CA2723650C

公开(公告)日：2016-06-28

申请号：CA2723650

申请日：2009-05-08

Applicant: BIO-RAD LABORATORIES INC

Inventor： PRICE GLENN ,  PANATTONI CORY ,  ROWELL CRAIG ,  PETERSEN SHANE ,  PEREZ EVELIO

IPC: G01N27/453

Abstract: A slab gel cassette is formed from generally flat plates welded together along their borders with a gel space between the plates that is open at the top and bottom edges of the plates to expose the opposing ends of a gel in the gel space to buffer solutions in which electrodes are immersed. The plates are shaped such that the weld line does not intersect with the bottom opening of the gel space. Sealing of the bottom of the gel space, which is necessary for gel casting, is achieved by placing a seal-ing strip over the bottom opening with no danger of leakage of the gel solution along a weld line.

公开(公告)号：CA2396970C

公开(公告)日：2010-05-11

申请号：CA2396970

申请日：2001-09-04

Applicant: BIO RAD LABORATORIES

Inventor： FERNWOOD GEORGE ,  WHITMAN CHRISTINA ,  HARBERS ADRIANA J ,  PEREZ EVELIO

IPC: G01N27/447 ,  B01D57/02 ,  B03C5/00

Abstract: Electrophoresis is performed simultaneously in a multitude of slab gels in a single cell that supports the slab gels vertically and parallel to each other while immersed in a buffer solution, and that applies a voltage to all gels simultaneously through a single pair of plate electrodes. Temperature control is achieved by circulating the buffer solution upward through the cell, entering near the base of each slab gel and leaving near the top, and cooling the circulating buffer solution with a tube heat exchanger positioned on the floor of the cell.

公开(公告)号：DE60034314D1

公开(公告)日：2007-05-24

申请号：DE60034314

申请日：2000-02-10

Applicant: BIO RAD LABORATORIES

Inventor： PEREZ EVELIO ,  FERNWOOD GEORGE

IPC: G01N27/447

Abstract: Flat plates serving as molds and enclosures for slab gels are held together by a clamping frame in which the side edges of the plates slide into facing channels and are clamped by lever-operated cams that compress the channel walls against the plate surfaces. The joined plates are held on a vertical support rack containing a finger-operated spring-loaded notched clamp that presses down on the plates to seal the opening at the bottom edges of the plates against a gasket. A well-forming comb for insertion between the plates contains flexible outwardly angled fingers to seal against the spacers between the plates.

公开(公告)号：DE03779509T1

公开(公告)日：2006-03-09

申请号：DE03779509

申请日：2003-11-06

Applicant: BIO RAD LABORATORIES

Inventor： PEREZ EVELIO ,  RODRIGUEZ GABRIELA

IPC: B01F11/00 ,  G01N1/31 ,  G01N27/447

Abstract: Slab gels held on trays are agitated in a staining or fixing solution by an apparatus that includes a tray carrier that holds a stack of slab gel trays, a tank that receives the tray carrier with sufficient excess room to allow the carrier to move back and forth within the tank, and a motor with a crankpin that is connected to the tray carrier in a reciprocating connection that translates the circular path of the crankpin into a linear path of movement of the tray carrier.

公开(公告)号：DE1277048T1

公开(公告)日：2003-08-14

申请号：DE01924783

申请日：2001-04-06

Applicant: BIO RAD LABORATORIES

Inventor： PEREZ EVELIO

IPC: B01D57/02 ,  B03C5/00 ,  G01N27/447

Abstract: Parallel plate slab gel enclosures (slab gel cassettes) used for vertical slab gel electrophoresis are secured to a frame to form a chamber for an upper buffer solution, and the securement is achieved by a pair of clamps that compress the cassettes against the frame. The clamps are preferably mounted to the frame in a pivotal connection that enables the user to easily rotate the clamps in and out of their clamping positions. An additional preferred feature is a pin protruding from each clamp in a position causing the pint to move upward against the bottom of the cassette and push the cassette upwards as the clamp is being engaged. This is particularly useful for cassettes formed of plates of unequal height where the shorter plate fits under an inverse shoulder on a gasket which thereby seals against both plates.

公开(公告)号：CA2396970A1

公开(公告)日：2002-03-14

申请号：CA2396970

申请日：2001-09-04

Applicant: BIO RAD LABORATORIES

Inventor： HARBERS ADRIANA J ,  PEREZ EVELIO ,  WHITMAN CHRISTINA ,  FERNWOOD GEORGE

IPC: B01D57/02 ,  B03C5/00 ,  G01N27/447

Abstract: Electrophoresis is performed simultaneously in a multitude of slab gels in a single cell that supports the slab gels vertically and parallel to each othe r while immersed in a buffer solution, and that applies a voltage to all gels simultaneously through a single pair of plate electrodes. Temperature contro l is achieved by circulating the buffer solution upward through the cell, entering near the base of each slab gel and leaving near the top, and coolin g the circulating buffer solution with a tube heat exchanger positioned on the floor of the cell.

公开(公告)号：CA2399752A1

公开(公告)日：2001-11-01

申请号：CA2399752

申请日：2001-04-06

Applicant: BIO RAD LABORATORIES

Inventor： PEREZ EVELIO

IPC: B01D57/02 ,  B03C5/00 ,  G01N27/447

Abstract: Parallel plate slab gel enclosures (slab gel cassettes) used for vertical sl ab gel electrophoresis are secured to a frame (14) to form a chamber for an upp er buffer solution, and the securement is achieved by a pair of clamps (16, 17) that compress the cassettes (12, 13) against the frame. The clamps are preferably mounted to the frame in a pivotal connection that enables the use r to easily rotate the clamps in and out of their clamping positions. An additional preferred feature is a pin protruding from each clamp in a positi on causing the pin to move upward against the bottom of the cassette and push t he cassette upwards as the clamp is being engaged. This is particularly useful for cassettes formed of plates of unequal height where the shorter plate fit s under an inverse shoulder on a gasket which thereby seals against both plate s.

公开(公告)号：EP2820676A4

公开(公告)日：2015-10-21

申请号：EP13755695

申请日：2013-01-14

Applicant: BIO RAD LABORATORIES

Inventor： HILLENDAHL JAMES W ,  PEREZ EVELIO

IPC: G01N21/25 ,  F21K99/00 ,  G01N21/64 ,  G01N27/447 ,  H01L33/08

CPC classification number: F21V21/005 ,  F21V9/083 ,  F21V13/02 ,  G01N21/255 ,  G01N21/6452 ,  G01N21/6456 ,  G01N27/447 ,  G01N2021/6463 ,  G01N2021/6471 ,  G01N2201/06 ,  G01N2201/0626 ,  G01N2201/0635

Abstract: A planar sample, particularly of the type used in biological laboratories for detection and sometimes analysis of two-dimensional arrays of proteins, nucleic acids, or other biological species, is illuminated by epi-illumination using optically filtered line lights that are arranged along opposing parallel sides of a rectangle in which the sample array resides, with two coaxial line lights on each side of the rectangle, and the two on any given side being separated by a gap whose optimal width depends on the wavelength band transmitted by the optical filter. Surprisingly, the gap eliminates the peak in intensity at the center of the sample area and the decrease that occurs from the center outward that would otherwise occur with a single continuous filtered line light, producing instead a substantially uniform intensity along the direction parallel to the line lights.

公开(公告)号：EP2277034A4

公开(公告)日：2011-10-19

申请号：EP09747252

申请日：2009-05-08

Applicant: BIO RAD LABORATORIES

Inventor： PRICE GLENN ,  PANATTONI CORY ,  ROWELL CRAIG ,  PETERSEN SHANE ,  PEREZ EVELIO

IPC: G01N27/26 ,  G01N27/447 ,  G01N27/453

CPC classification number: G01N27/453 ,  G01N27/44704 ,  G01N27/44756