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公开(公告)号：GB2363378A
公开(公告)日：2001-12-19
申请号：GB0120083
申请日：2000-02-24
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , GRAY WILLIAM KEITH , SWAN THOMAS MACKLYN , ROSS STEPHEN KEITH , WIELAND STEFAN
IPC: C07C1/24 , C07C41/09 , C07C41/56 , C07D307/08 , C07D317/12 , C07C1/20 , C07C41/50
Abstract: The present invention relates to methods for inhibiting cathepsin K activity in a mammal in need thereof comprising administering a nitric oxide donor compound having cathepsin K inhibition activity. The present invention also relates to methods for inhibiting bone resorption in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of such a nitric oxide donor. The present invention also relates to compositions comprising such a nitric oxide donor.
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公开(公告)号：BR9911999A
公开(公告)日：2001-03-27
申请号：BR9911999
申请日：1999-06-30
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND SFEFAN , ROEDER STEFAN
Abstract: In a process for the hydroformylation of alkanes, alkenes or trialkylboranes under supercritical or near-critical conditions, hydroformylation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation may be achieved by independently varying one of more of the temperature, pressure, catalyst, mole ratios of hydrogen and carbon monoxide and flow rate.
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公开(公告)号：GB2332905B
公开(公告)日：2000-08-23
申请号：GB9905939
申请日：1997-09-29
Applicant: THOMAS SWAN & COMPANY LIMITED , DEGUSSA
Inventor： SWAN THOMAS MACKLYN , ROSS STEPHEN KEITH , POLIAKOFF MARTYN , HITZLER MARTIN GEORG , SMAIL FIONA RUTH , TACKE THOMAS , WIELAND STEFAN
IPC: B01J3/00 , C07B37/02 , C07B37/04 , C07B41/06 , C07B61/00 , C07C2/66 , C07C2/70 , C07C2/86 , C07C15/02 , B01J31/06 , C07C41/30 , C07C43/205 , C07C45/46 , C07C37/14 , C07C37/16
Abstract: A process for the alkylation of aromatic substrates under supercritical or near-critical reaction conditions is described. In particular, a method for performing Friedel-Crafts alkylation reactions is disclosed under those conditions. Friedel-Crafts reactions may be effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation can be achieved by varying one or more of temperature, pressure, catalyst, flow rates and also by varying the ratios of aromatic substrate to alkylating agent.
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公开(公告)号：NO984844L
公开(公告)日：1998-12-17
申请号：NO984844
申请日：1998-10-16
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , SWAN THOMAS M , TACKE THOMAS , HITZLER MARTIN G , ROSS STEPHEN K , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66
Abstract: PCT No. PCT/GB97/01014 Sec. 371 Date Feb. 18, 1999 Sec. 102(e) Date Feb. 18, 1999 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/38955 PCT Pub. Date Oct. 23, 1997Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.
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公开(公告)号：NO984844D0
公开(公告)日：1998-10-16
申请号：NO984844
申请日：1998-10-16
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , SWAN THOMAS M , TACKE THOMAS , HITZLER MARTIN G , ROSS STEPHEN K , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66 , C07B
Abstract: PCT No. PCT/GB97/01014 Sec. 371 Date Feb. 18, 1999 Sec. 102(e) Date Feb. 18, 1999 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/38955 PCT Pub. Date Oct. 23, 1997Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.
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Patent Agency Ranking
公开(公告)号：ZA978764B
公开(公告)日：1998-03-27
申请号：ZA978764
申请日：1997-09-30
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , SWAN THOMAS MACKLYN , TACKE THOMAS , HITZLER MARTIN GEORG , ROSS STEPHEN KEITH , WIELAND STEFAN , SMAIL FIONA RUTH
IPC: B01J3/00 , C07B37/02 , B01J31/06 , C07B37/04 , C07B41/06 , C07B61/00 , C07C2/66 , C07C2/70 , C07C2/86 , C07C15/02 , C07C41/30 , C07C43/205 , C07C45/46 , C07B , B01J
Abstract: A process for the alkylation of aromatic substrates under supercritical or near-critical reaction conditions is described. In particular, a method for performing Friedel-Crafts alkylation reactions is disclosed under those conditions. Friedel-Crafts reactions may be effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation can be achieved by varying one or more of temperature, pressure, catalyst, flow rates and also by varying the ratios of aromatic substrate to alkylating agent.
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公开(公告)号：ZA973204B
公开(公告)日：1997-11-14
申请号：ZA973204
申请日：1997-04-15
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , TACKE THOMAS , ROSS STEPHEN K , SWAN THOMAS M , HITZLER MARTIN G , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66 , C07B , C10G
Abstract: PCT No. PCT/GB97/01014 Sec. 371 Date Feb. 18, 1999 Sec. 102(e) Date Feb. 18, 1999 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/38955 PCT Pub. Date Oct. 23, 1997Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.
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公开(公告)号：NO20014268A
公开(公告)日：2001-11-02
申请号：NO20014268
申请日：2001-09-03
Applicant: DEGUSSA
Inventor： POLIAKOFF MARTYN , ROSS STEPHEN KEITH , ROEDER STEFAN , GRAY WILLIAM KEITH , SWAN THOMAS MACKLYN , WIELAND STEFAN
IPC: C07C1/24 , C07C41/09 , C07C41/56 , C07D307/08 , C07D317/12 , C07C41/50
CPC classification number: C07D317/12 , C07C1/24 , C07C41/09 , C07D307/08 , Y02P20/544 , C07C11/10 , C07C43/04 , C07C43/13 , C07C43/10
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公开(公告)号：NO20006712A
公开(公告)日：2001-03-01
申请号：NO20006712
申请日：2000-12-29
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND STEFAN , ROEDER STEFAN
CPC classification number: C07C45/50 , Y02P20/544 , C07C47/02
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公开(公告)号：GB2326640B
公开(公告)日：2000-11-22
申请号：GB9817801
申请日：1997-04-11
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor： POLIAKOFF MARTYN , SWAN THOMAS MACKLYN , TACKE THOMAS , HITZLER MARTIN GEORG , ROSS STEPHEN KEITH , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66
Abstract: PCT No. PCT/GB97/01014 Sec. 371 Date Feb. 18, 1999 Sec. 102(e) Date Feb. 18, 1999 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/38955 PCT Pub. Date Oct. 23, 1997Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.
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