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    SYSTEMS AND METHODS FOR MAKING TIME-SEQUENTIAL MEASUREMENTS OF BIOLOGICAL EVENTS
    22.
    发明申请
    SYSTEMS AND METHODS FOR MAKING TIME-SEQUENTIAL MEASUREMENTS OF BIOLOGICAL EVENTS 审中-公开
    制作生物事件时间序列测量的系统和方法

    公开(公告)号：WO1996025095A1

    公开(公告)日：1996-08-22

    申请号：PCT/US1996002090

    申请日：1996-02-14

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin

    IPC: A61B05/0402

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/6858 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056 ,  A61N1/3702 ,  A61N1/403

    Abstract: Analog or digital systems (10) and methods generate a composite signal derived from a biological event in a time sequential fashion. A first set of signals derived from a biological event using a first group of sensors (20) during a first time interval is input. A second set of signals derived from the biological event during a second time interval sequentially after the first time interval using a second group of sensors (36) is input. The second group of sensors has at least one common sensor that is part of the first group and other sensors that are not part of the first group. The first and second sets of signals are time aligned using signals sensed by the at least one common sensor, thereby generating the composite signal. The time alignment is done by shifting the first and second sets of signals either with or without computing a time difference between them.

    Abstract translation: 模拟或数字系统（10）和方法以时间顺序的方式产生从生物事件导出的复合信号。 输入在第一时间间隔期间使用第一组传感器（20）从生物事件导出的第一组信号。 输入使用第二组传感器（36）在第一时间间隔之后的第二时间间隔期间从生物事件导出的第二组信号。 第二组传感器具有至少一个共同的传感器，其是第一组的一部分和不是第一组的一部分的其它传感器。 使用由至少一个公共传感器感测的信号来对第一和第二组信号进行时间对准，从而产生复合信号。 时间对准是通过移动第一和第二组信号来完成的，无论是否计算它们之间的时间差。

    SYSTEM FOR EXAMINING CARDIAC TISSUE ELECTRICAL CHARACTERISTICS
    26.
    发明申请
    SYSTEM FOR EXAMINING CARDIAC TISSUE ELECTRICAL CHARACTERISTICS 审中-公开
    检查心脏组织电学特征的系统

    公开(公告)号：WO1995020344A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001085

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  MIROTZNIK, Mark, S. ,  SCHWARTZMAN, David, S. ,  FOSTER, Kenneth, R.

    IPC: A61B05/04

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/05 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/6858 ,  A61B18/00 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

    Abstract: Systems and methods examine heart tissue morphology using three or more spaced apart electrodes (38), at least two of which are located within the heart (12) in contact with endocardial tissue. The systems and methods transmit electrical current through a region of heart tissue lying between selected pairs of the electrodes (38), at least one of the electrodes (38) in each pair being located within the heart (12). The systems and methods derive the electrical characteristic of tissue lying between the electrode (38) pairs based, at least in part, upon sensing tissue impedances. The systems and methods make possible the use of multiple endocardial electrodes (38) for making multiple measurements of the electrical characteristics of heart tissue. Multiplexing can be used to facilitate date processing. The systems and methods almost make possible the identification of regions of low relative electrical characteristics, indicative of infarcted tissue, without invasive surgical techniques.

    Abstract translation: 系统和方法使用三个或更多个间隔开的电极（38）检查心脏组织形态，其中至少两个电极位于与心内膜组织接触的心脏（12）内。 系统和方法通过位于选定的电极对（38）之间的心脏组织的区域传输电流，每对电极（38）中的至少一个位于心脏（12）内。 系统和方法至少部分地基于感测组织阻抗而导出位于电极（38）对之间的组织的电特性。 系统和方法使得可以使用多个心内膜电极（38）来进行心脏组织的电特性的多个测量。 可以使用多路复用来进行日期处理。 系统和方法几乎可以识别低相对电特征的区域，指示梗死组织，无侵入性手术技术。

    MULTI-FUNCTION ELECTRODE STRUCTURES FOR ELECTRICALLY ANALYZING AND HEATING BODY TISSUE
    29.
    发明申请
    MULTI-FUNCTION ELECTRODE STRUCTURES FOR ELECTRICALLY ANALYZING AND HEATING BODY TISSUE 审中-公开
    用于电动分析和加热身体组织的多功能电极结构

    公开(公告)号：WO1997025917A1

    公开(公告)日：1997-07-24

    申请号：PCT/US1997000896

    申请日：1997-01-17

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  WHAYNE, James, G. ,  JACKSON, Jerome

    IPC: A61B05/04

    CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/1472 ,  A61B2218/002 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  C08L1/02

    Abstract: Systems and methods for heating body tissue places a multi-function structure (22) having an exterior wall in contact with body tissue. The structure includes an array of electrically conducting electrode segments (44) carried by the exterior wall. An electrically conductive network is coupled to the electrode segments, including at least one electrically conductive path (32) individually coupled to each electrode segment. The systems and methods operate in a first mode during which the network is electrically conditioned to individually sense at each electrode segment local electrical events in tissue, such as electrical potentials, resistivity, or impedance. The systems and methods operate in a second mode during which the network is electrically conditioned, based at least in part upon local electrical events sensed by the electrode segments, to couple at least two electrode segments together to simultaneously trasmit electrical energy to heat or ablate a region of body tissue.

    Abstract translation: 用于加热身体组织的系统和方法将具有外壁的多功能结构（22）与身体组织接触。 该结构包括由外壁承载的导电电极段（44）阵列。 导电网络耦合到电极段，包括分别耦合到每个电极段的至少一个导电路径（32）。 系统和方法以第一模式操作，在该模式期间，网络经电气调节以在每个电极段处单独感测组织中的局部电气事件，例如电势，电阻率或阻抗。 系统和方法在第二模式下操作，其中网络被电调节，至少部分地基于由电极段感测的局部电气事件，以将至少两个电极段耦合在一起，以同时对电能进行加热或消融 身体组织区域。

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