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公开(公告)号:CA644656A
公开(公告)日:1962-07-10
申请号:CA644656D
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , REUTER MARTIN , JUNGHANNS ERNST
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22.
公开(公告)号:CA1136646A
公开(公告)日:1982-11-30
申请号:CA339893
申请日:1979-11-15
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , SCHAEFFER GEORG
IPC: B01J27/00 , C07B61/00 , C07C17/00 , C07C17/14 , C07C22/04 , C07C25/02 , C07C25/13 , C07C51/00 , C07C51/093 , C07C63/04 , C07C63/70 , C07C67/00
Abstract: of the disclosure: p-Tert.butlbenzotribromide and the derivatives thereof halogen-substituted at the nucleus are prepared under side chain halogenation conditions by bromination of ptert.butyltoluene and its derivatives substituted at the nucleus by halogen. Practically no undesired bromination in the nucleus or at the tert.butyl radical takes place. By partical saponification of the benzotribromine the corresponding benzoyl bromide is obtained. Further saponification of the latter or complete saponification of the benzotribromide yeilds p-tert.butylbenzoic acid and derivatives thereof halogen substituted at the nucleus, the ester of which can be used in pharmacology.
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公开(公告)号:DE2857580A1
公开(公告)日:1980-07-31
申请号:DE2857580
申请日:1978-11-16
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , SCHAEFFER GEORG
IPC: A61K31/18 , A61P9/00 , B01J27/00 , C07B61/00 , C07C17/00 , C07C17/14 , C07C22/04 , C07C25/02 , C07C25/13 , C07C45/00 , C07C45/43 , C07C45/80 , C07C45/82 , C07C45/85 , C07C47/542 , C07C47/55 , C07C67/00 , C07C25/14
Abstract: In the prodn. of p-tert. -butyl-benzaldehyde and its halogenated derivs. of formula (I), opt. halogenated p-tert. butyl-toluene of formula (II) is first reacted with approx. 2 mol. Br2/mol. (II) at 40-200 degrees C, pref. 40-120 degrees C, opt. using high energy radiation or radical formers, to form an opt. halogenated p-tert. butylbenzal bromide of formula (III). (III) is then saponified with water at elevated temp. in the presence of standard saponification catalysts. In the formulae, X=H, F, Cl, Br to I. Cpds. (III) are new (I) are useful intermediates in the prodn. of pharmaceuticals, plant protection agents, dyes and aroma substances.
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公开(公告)号:AU5280979A
公开(公告)日:1980-05-22
申请号:AU5280979
申请日:1979-11-14
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , SCHAEFFER GEORG
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公开(公告)号:CA951327A
公开(公告)日:1974-07-16
申请号:CA96145
申请日:1970-10-21
Applicant: HOECHST AG
Inventor: BEERMANN CLAUS , LANDAUER FRANZ , SCHOEN FRANZ , WECKLER GERHARD
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公开(公告)号:CA862055A
公开(公告)日:1971-01-26
申请号:CA862055D
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , BEERMANN CLAUS , KIESLING HUBERT , LEBKUCHER KARL H , REUTER MARTIN
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公开(公告)号:CA787495A
公开(公告)日:1968-06-11
申请号:CA787495D
Applicant: HOECHST AG
Inventor: SCHMIDT ERWIN , BEERMANN CLAUS , LANDAUER FRANZ , LOHAUS GERHARD
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28.
公开(公告)号:CA767007A
公开(公告)日:1967-09-12
申请号:CA767007D
Applicant: HOECHST AG
Inventor: WECKLER GERHARD , LANDAUER FRANZ , REUTER MARTIN
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公开(公告)号:CA695422A
公开(公告)日:1964-10-06
申请号:CA695422D
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ , HERZBERG HORST , ORTHNER LUDWIG
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公开(公告)号:HUT42050A
公开(公告)日:1987-06-29
申请号:HU235385
申请日:1985-06-14
Applicant: HOECHST AG
Inventor: LANDAUER FRANZ
IPC: C07C51/363 , C07C53/19
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