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    Process for the preparation of 3,4-dihydro-1,2,3-oxathiazin-4-ones
    1.
    发明授权
    Process for the preparation of 3,4-dihydro-1,2,3-oxathiazin-4-ones 失效
    制备3,4-二氢-1,2,3-氧代西他嗪-4-酮的方法

    公开(公告)号：US3689485A

    公开(公告)日：1972-09-05

    申请号：US3689485D

    申请日：1971-01-07

    Applicant: HOECHST AG

    Inventor： CLAUSS KARL ,  LOHAUS GERHARD

    IPC: C07D291/06 ,  C07D95/00

    CPC classification number: C07D291/06

    Abstract: 3,4-DIHYDRO-1,2,3-OXATHIAZINONES ARE OBTAINED WHEN REACTING KETONES WITH ARYLOXYSULFONYL ISOCYANATES. THE COMPOUNDS HAVING LOW-MOLECULAR SUBSTITUENTS ARE ARTIFICIAL SWEETENING AGENTS AND THE DERIVATIVES HAVING HYDROPHOBIC SUBSTITUENTS ARE INTERFACIAL ACTIVE AGENTS. ALL OF THE NEW COMPOUNDS ARE ORGANIC INTERMEDIATES HAVING A PLURALITY OF REACTIVE GROUPS.

    Certain 1-hydroxy-2-pyridones
    2.
    发明授权
    Certain 1-hydroxy-2-pyridones 失效
    某些1-羟基-2-吡啶酮

    公开(公告)号：US3883545A

    公开(公告)日：1975-05-13

    申请号：US31738772

    申请日：1972-12-22

    Applicant: HOECHST AG

    Inventor： LOHAUS GERHARD ,  DITTMAR WALTER

    IPC: C07D213/89 ,  C07D31/30

    CPC classification number: C07D213/89

    Abstract: New 1-hydroxy-2-pyridones of the general formula
    IN WHICH R1 is alkyl of 1 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, cyclohexylalkyl or phenalkyl both having 1 to 3 carbon atoms in the alkylene chain or Alpha -furyl, all of which may be substituted by halogen and R2 to R4 are hydrogen or lower alkyl or 2 adjacent substituents together form a trimethylene or tetramethylene chain, and in which R1 to R4 together contain at least 2 carbon atoms, are prepared by contacting unsaturated delta -keto esters or mixtures thereof with hydroxylamine and subjecting the products to cyclization. The compounds exhibit antimycotic properties.

    Abstract translation: 新的具有1至17个碳原子的烷基，5至8个碳原子的环烷基，环烷基或苯烷基，其中亚烷基链中具有1至3个碳原子的α-羟基-2-吡啶酮或α-呋喃基 所有这些可以被卤素取代，并且R 2至R 4是氢或低级烷基或2个相邻的取代基一起形成三亚甲基或四亚甲基链，并且其中R 1至R 4一起含有至少2个碳原子，通过使不饱和三 - 酯或其与羟胺的混合物，并使产物环化。

    Substituted 2-pyrones
    4.
    发明授权
    Substituted 2-pyrones 失效
    取代的2-PYRONES

    公开(公告)号：US3872109A

    公开(公告)日：1975-03-18

    申请号：US44628974

    申请日：1974-02-27

    Applicant: HOECHST AG

    Inventor： FURRER HARALD ,  LOHAUS GERHARD

    IPC: C07D309/38 ,  G03F7/038 ,  C07D7/16

    CPC classification number: C07D309/38 ,  G03F7/0388

    Abstract: Novel substituted 2-pyrones

    IN WHICH ONE OF THE RADICALS R1 to R4 is substituted by an acryloyl or methacryloyl group are obtained from the corresponding 2-pyrone derivatives and acrylic or methacrylic acid or a derivative thereof. The compounds can be polymerized forming light-sensitive polymers which are cross-linked by the action of light and may be used in light-sensitive copying layers.

    Abstract translation: 获自相应的2-吡喃酮衍生物和丙烯酸或甲基丙烯酸或其衍生物的新型取代的2-吡咯烷酮其中R 1至R 4中的一个被丙烯酰基或甲基丙烯酰基取代。 化合物可以聚合形成通过光的作用交联的感光聚合物，并可用于光敏复印层。

    1-HYDROXY-2-PYRIDONE DERIVATIVES
    6.
    发明专利
    1-HYDROXY-2-PYRIDONE DERIVATIVES 未知

    公开(公告)号：AU7171787A

    公开(公告)日：1987-10-22

    申请号：AU7171787

    申请日：1987-04-16

    Applicant: HOECHST AG

    Inventor： LOHAUS GERHARD ,  GROBEL BENGT-THOMAS ,  DITTMAR WALTER ,  HANEL HEINZ ,  RAETHER WOLFGANG ,  REUSCHLING DIETER

    IPC: A61K31/44 ,  C07D213/89 ,  C07D309/38 ,  A01N43/40

    Abstract: New 1-hydroxy-2-pyridones of the general formula I I in which R1, R2 and R3, which are identical or different, denote hydrogen or lower alkyl having 1-4 carbon atoms, R1 and R3 preferably being hydrogen, and R2 preferably being methyl, X denotes S or, preferably, O, Y denotes hydrogen or up to 2 halogen atoms, namely chlorine and/or bromine, Z denotes a single bond or the bivalent radicals O, S, -CR2- (R=H or C1-C4-alkyl) or other 2-valent radicals with 2-10 carbon and, optionally, oxygen and/or sulfur atoms linked to form a chain, it being obligatory when the radicals contain 2 or more oxygen and/or sulfur atoms for the latter to be separated by at least 2 carbon atoms, and it being possible for 2 adjacent carbon atoms also to be linked together by a double bond, and the free valencies of the carbon atoms being saturated by H and/or C1-C4-alkyl groups, Ar denotes an aromatic ring system which has up to two rings and can be substituted by up to three radicals from the group comprising fluorine, chlorine, bromine, methoxy, C1-C4-alkyl, trifluoromethyl and trifluoromethoxy, are prepared by a variety of process variants. The compounds and their physiologically tolerated salts with inorganic or organic bases mainly have antimycotic, anti-bacterial and antiviral activity. The compounds of the formula V V in which R1, R2, R3, X, Y, Z and Ar have the same meaning as in formula I, which occur in the preparation of the compounds of the formula I, are also new.

    7.
    发明专利
    未知

    公开(公告)号：NO871602L

    公开(公告)日：1987-10-19

    申请号：NO871602

    申请日：1987-04-15

    Applicant: HOECHST AG

    Inventor： LOHAUS GERHARD ,  DITTMAR WALTER ,  HANEL HEINZ ,  RAETHER WOLFGANG ,  REUSCHLING DIETER ,  GROBEL BENGT-THOMAS

    IPC: A61K31/44 ,  C07D213/89 ,  C07D309/38 ,  C07D213/00

    Abstract: New 1-hydroxy-2-pyridones of the general formula I I in which R1, R2 and R3, which are identical or different, denote hydrogen or lower alkyl having 1-4 carbon atoms, R1 and R3 preferably being hydrogen, and R2 preferably being methyl, X denotes S or, preferably, O, Y denotes hydrogen or up to 2 halogen atoms, namely chlorine and/or bromine, Z denotes a single bond or the bivalent radicals O, S, -CR2- (R=H or C1-C4-alkyl) or other 2-valent radicals with 2-10 carbon and, optionally, oxygen and/or sulfur atoms linked to form a chain, it being obligatory when the radicals contain 2 or more oxygen and/or sulfur atoms for the latter to be separated by at least 2 carbon atoms, and it being possible for 2 adjacent carbon atoms also to be linked together by a double bond, and the free valencies of the carbon atoms being saturated by H and/or C1-C4-alkyl groups, Ar denotes an aromatic ring system which has up to two rings and can be substituted by up to three radicals from the group comprising fluorine, chlorine, bromine, methoxy, C1-C4-alkyl, trifluoromethyl and trifluoromethoxy, are prepared by a variety of process variants. The compounds and their physiologically tolerated salts with inorganic or organic bases mainly have antimycotic, anti-bacterial and antiviral activity. The compounds of the formula V V in which R1, R2, R3, X, Y, Z and Ar have the same meaning as in formula I, which occur in the preparation of the compounds of the formula I, are also new.

    8.
    发明专利
    未知

    公开(公告)号：PT84702A

    公开(公告)日：1987-05-01

    申请号：PT8470287

    申请日：1987-04-16

    Applicant: HOECHST AG

    Inventor： LOHAUS GERHARD ,  DITTMAR WALTER ,  HAENEL HEINZ ,  RAETHER WOLFGANG ,  REUSCHLING DIETER ,  GROEBEL BENGT-THOMAS

    IPC: A61K31/44 ,  C07D213/89 ,  C07D309/38 ,  C07D211/00 ,  C07D309/00

    Abstract: New 1-hydroxy-2-pyridones of the general formula I I in which R1, R2 and R3, which are identical or different, denote hydrogen or lower alkyl having 1-4 carbon atoms, R1 and R3 preferably being hydrogen, and R2 preferably being methyl, X denotes S or, preferably, O, Y denotes hydrogen or up to 2 halogen atoms, namely chlorine and/or bromine, Z denotes a single bond or the bivalent radicals O, S, -CR2- (R=H or C1-C4-alkyl) or other 2-valent radicals with 2-10 carbon and, optionally, oxygen and/or sulfur atoms linked to form a chain, it being obligatory when the radicals contain 2 or more oxygen and/or sulfur atoms for the latter to be separated by at least 2 carbon atoms, and it being possible for 2 adjacent carbon atoms also to be linked together by a double bond, and the free valencies of the carbon atoms being saturated by H and/or C1-C4-alkyl groups, Ar denotes an aromatic ring system which has up to two rings and can be substituted by up to three radicals from the group comprising fluorine, chlorine, bromine, methoxy, C1-C4-alkyl, trifluoromethyl and trifluoromethoxy, are prepared by a variety of process variants. The compounds and their physiologically tolerated salts with inorganic or organic bases mainly have antimycotic, anti-bacterial and antiviral activity. The compounds of the formula V V in which R1, R2, R3, X, Y, Z and Ar have the same meaning as in formula I, which occur in the preparation of the compounds of the formula I, are also new.

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