Abstract:
Ketones are prepared by reacting carboxylic acid halides, in particular carboxylic acid chlorides, with aluminum-alkyl compounds, optionally in the presence of an aluminum trihalide, in methylene chloride as the solvent, at a temperature between about 20 DEG and about 100 DEG C., preferably between about 30 DEG and about 60 DEG C., more preferably of about 40 DEG C. which is the reflux temperature of the methylene chloride. When operating at a temperature above approximately 40 DEG C., pressure higher than atmospheric is applied. The reaction mixture is worked up in usual manner, suitably by decomposition with water followed by distillation.
Abstract:
Arylhydroxy compounds and aqueous alkali metal hydroxide solutions are separated and isolated from aqueous solutions of alkali metal arylates by extracting at a temperature of from 15 DEG to 150 DEG C. an aqueous solution containing the alkali metal arylate with a ketone immiscible or incompletely miscible with water at room temperature, separating the organic phase from the aqueous phase containing the alkali metal hydroxide, and isolating the free arylhydroxy compound from the organic phase by removing the ketone used as solvent.
Abstract:
2-Nitro-3-aminopyridine is prepared by nitrating N,N'-di- (3-pyridyl)-urea, with subsequent hydrolysis. N,N'-Di-(2-nitro-3-pyridyl)-urea, which is formed in the course of the reaction as an intermediate, is a new compound. The end product of the process, 2-nitro-3-aminopyridine, is principally an intermediate in various specialized fields, for example, in the pharmaceutical, dyestuff and plant protection sectors.