公开(公告)号：ES2063770T3

公开(公告)日：1995-01-16

申请号：ES89101441

申请日：1989-01-27

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  SHIRAKAWA NORIKO ,  TSUTSUMI HISAO

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/26 ,  A61K8/55 ,  A61K8/58 ,  A61K47/00 ,  A61K47/12 ,  A61K47/24 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/12 ,  A61Q19/00 ,  C07F9/09 ,  C07F9/11 ,  C07F19/00 ,  C09D7/12 ,  A61K7/48

Abstract: A a polyaluminum dialkyl phosphate is discosed. The compound is prepared by the reaction of: (A) a dialkyl phosphate represented by formula (I): wherein R1 and R2 independently represent a hydrocarbon group of a C8-26 carbon atom content, or a salt thereof, and (B) a basic polyaluminum salt represented by formula (II): Alm(OH)nX1.kH2O (II) wherein X represents an anion having a valency of x other than a hydroxyl ion, m represents a positive integer satisfying the equation: 3m = n + x1, and k represents 0 or a positive integer, in an aqueous medium in which the resulting polyaluminum dialkyl phosphate is insoluble. The polyaluminum dialkyl phosphate, when it is formulated into a liquid oil, provides a highly transparent, densely structured, soft gel which contains only small amount of free oil component. The gel posseses favorable rheological characteristics and can adequately disperse by a stress and imparts a good feeling upon use.

公开(公告)号：DE3578121D1

公开(公告)日：1990-07-19

申请号：DE3578121

申请日：1985-01-28

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  KATO HARUYA ,  IWAYA KATSUMASA ,  SHIMIZU TAKAKO ,  KAWANO ATSUSHI

IPC: A61K8/00 ,  A61K8/11 ,  A61K8/26 ,  A61K8/55 ,  A61K8/58 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q19/00 ,  A61K7/48 ,  A61K7/035

Abstract: A cosmetic comprises an alkyl phosphate represented by the formula (I):in which R, and R 2 independently represent hydrogen atom or an alkyl group having from 1 to 36 carbon atoms, and R 3 represents an alkyl group having from 1 to 36 carbon atoms, and a cosmetic powder.The cosmetic is water-repellent in nature, unlikely to break by sweat and is readily spread on the skin with improved softness due to incorporation of the alkyl phosphate.The cosmetic is prepared by first mixing the cosmetic powder and the alkyl phosphate dissolved in an organic solvent under heating conditions. Subsequently, the solvent is distilled off to form an alkyl phosphate coating on the indivisual particles. The coated particles are mixed with other cosmetic ingredients.

公开(公告)号：PH23347A

公开(公告)日：1989-07-14

申请号：PH33875

申请日：1986-06-10

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  YASUDA YUTAKA ,  SATO YUJI ,  SHIDA JUN

IPC: A61K8/81 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q3/02 ,  A61K7/00

Abstract: A cosmetic composition acts as a film former resistant to various effects and comprises a copolymer of a fluoroalkyl (meth)acrylate and a long chain, linear alkyl (meth)acrylate. It may further comprise a volatile oil one or more solid fats.

公开(公告)号：DE69328575D1

公开(公告)日：2000-06-08

申请号：DE69328575

申请日：1993-02-05

Applicant: KAO CORP

Inventor： MIZUSHIMA HIROMOTO ,  FUKASAWA JUNICHI

IPC: A61K31/575 ,  C07J9/00 ,  A61K7/48

Abstract: This invention describes a dermatologic external preparation having an excellent effect of remedying the chaps of the skin, and being capable of stabilizing the lamellar liquid crystal structure, which comprises a ceramide and/or a structual analog of a ceramide, and one or more sterol derivatives represented by the formulas (V) or (VI): wherein R represents a residue remaining after removing the hydrogen atom from the hydroxyl group of a natural sterol having one hydroxyl group or a hydrogenation product thereof, R represents -(CH2)n- (n is an integer of 2 to 10) or - CH = CH -, M represents a hydrogen atom, alkali metal, ammonium, alkanol ammonium having 2 to 9 C-atoms in total, alkylammonium or alkenylammonium having 1 to 22 C-atoms in total, pyridinium which may be substituted by an alkyl or alkenyl group having 1-18 C-atoms, or basic amino acid, and L represents an alkaline earth metal.

公开(公告)号：ES2139609T3

公开(公告)日：2000-02-16

申请号：ES93101837

申请日：1993-02-05

Applicant: KAO CORP

Inventor： MIZUSHIMA HIROMOTO ,  FUKASAWA JUNICHI

IPC: A61K31/575 ,  C07J9/00 ,  A61K7/48

Abstract: This invention describes a dermatologic external preparation having an excellent effect of remedying the chaps of the skin, and being capable of stabilizing the lamellar liquid crystal structure, which comprises a ceramide and/or a structual analog of a ceramide, and one or more sterol derivatives represented by the formulas (V) or (VI): wherein R represents a residue remaining after removing the hydrogen atom from the hydroxyl group of a natural sterol having one hydroxyl group or a hydrogenation product thereof, R represents -(CH2)n- (n is an integer of 2 to 10) or - CH = CH -, M represents a hydrogen atom, alkali metal, ammonium, alkanol ammonium having 2 to 9 C-atoms in total, alkylammonium or alkenylammonium having 1 to 22 C-atoms in total, pyridinium which may be substituted by an alkyl or alkenyl group having 1-18 C-atoms, or basic amino acid, and L represents an alkaline earth metal.

公开(公告)号：DE69326569T2

公开(公告)日：2000-02-03

申请号：DE69326569

申请日：1993-02-05

Applicant: KAO CORP

Inventor： MIZUSHIMA HIROMOTO ,  FUKASAWA JUNICHI

IPC: A61K31/575 ,  C07J9/00 ,  A61K7/48

Abstract: This invention describes a dermatologic external preparation having an excellent effect of remedying the chaps of the skin, and being capable of stabilizing the lamellar liquid crystal structure, which comprises a ceramide and/or a structual analog of a ceramide, and one or more sterol derivatives represented by the formulas (V) or (VI): wherein R represents a residue remaining after removing the hydrogen atom from the hydroxyl group of a natural sterol having one hydroxyl group or a hydrogenation product thereof, R represents -(CH2)n- (n is an integer of 2 to 10) or - CH = CH -, M represents a hydrogen atom, alkali metal, ammonium, alkanol ammonium having 2 to 9 C-atoms in total, alkylammonium or alkenylammonium having 1 to 22 C-atoms in total, pyridinium which may be substituted by an alkyl or alkenyl group having 1-18 C-atoms, or basic amino acid, and L represents an alkaline earth metal.

公开(公告)号：DE3688895T2

公开(公告)日：1993-12-09

申请号：DE3688895

申请日：1986-06-12

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  YASUDA YUTAKA ,  SATO YUJI ,  SHIDA JUN

IPC: A61K8/81 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q3/02 ,  A61K7/027 ,  A61K7/11

Abstract: A cosmetic composition acts as a film former resistant to various effects and comprises a copolymer of a fluoroalkyl (meth)acrylate and a long chain, linear alkyl (meth)acrylate. It may further comprise a volatile oil one or more solid fats.

公开(公告)号：HK33791A

公开(公告)日：1991-05-10

申请号：HK33791

申请日：1991-05-02

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  KATO HARUYA ,  IWAYA KATSUMASA ,  SHIMIZU TAKAKO ,  KAWANO ATSUSHI

IPC: A61K8/00 ,  A61K8/11 ,  A61K8/26 ,  A61K8/55 ,  A61K8/58 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q19/00 ,  A61K7/48 ,  A61K7/035

Abstract: A cosmetic comprises an alkyl phosphate represented by the formula (I):in which R, and R 2 independently represent hydrogen atom or an alkyl group having from 1 to 36 carbon atoms, and R 3 represents an alkyl group having from 1 to 36 carbon atoms, and a cosmetic powder.The cosmetic is water-repellent in nature, unlikely to break by sweat and is readily spread on the skin with improved softness due to incorporation of the alkyl phosphate.The cosmetic is prepared by first mixing the cosmetic powder and the alkyl phosphate dissolved in an organic solvent under heating conditions. Subsequently, the solvent is distilled off to form an alkyl phosphate coating on the indivisual particles. The coated particles are mixed with other cosmetic ingredients.

公开(公告)号：PH22946A

公开(公告)日：1989-02-03

申请号：PH33729

申请日：1986-05-02

Applicant: KAO CORP

Inventor： FUKASAWA JUNICHI ,  INA YOSHIMITSU ,  TSUTSUMI HISAO

IPC: A61K8/02 ,  A61K8/06 ,  A61K8/55 ,  A61K8/58 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/12 ,  A61Q19/00 ,  A61K7/00

Abstract: A novel cosmetic comprises an oil gel formed by at least one metal salt of a dialkyl phosphate of the following general formula (I), (II) or (III) (I) (II) (III) in which each R1 and each R2 independently represent a saturated or unsaturated, linear or branched hydrocarbon group having from 8 to 36 carbon atoms, m is an integer of from 1 to 3, n is an integer of from 0 to 2, k is a value of 1 or 2, and 1 is a value of 0 to 1, and a cosmetic oil. The metal salt of the dialkyl phosphate can yield a good oil gel when it is incorporated into the oil in an amount as small as 0.1 to 10% of the oil. Further, the dialkyl phosphate retains good feel of oils without causing oozing of the oil, crazing, discoloration, perspiration and the like.

公开(公告)号：GB2160527B

公开(公告)日：1988-02-17

申请号：GB8512851

申请日：1985-05-21

Applicant: KAO CORP

Inventor： IMAMURA TAKASHI ,  NISHIGAWA NORIO ,  KUROSAKI TOMIHIRO ,  FUKASAWA JUNICHI ,  KATO HARUYA

IPC: A61K8/55 ,  A61Q1/02 ,  A61Q1/10 ,  C07F9/09 ,  C07F9/11 ,  A61K7/00 ,  C07F9/113

Abstract: Metal salts of monoalkyl phosphates of the following formula (I) in which each R represents a saturated or unsaturated, linear or branched hydrocarbon group having from 8 to 32 carbon atoms, and M represents an alkaline earth metal or divalent transition metal. The metal salts are particularly suitable as cosmetic powders, fillers for resins, and lubricants, parting agents and pigment dispersants for polymeric compounds. When used as cosmetic powders, the metal salts improve spreadability, moistness, smoothness, adherence, transparency and covering power of cosmetics. Preparation process of the metal salts is also disclosed.