公开(公告)号：JPH045671B2

公开(公告)日：1992-02-03

申请号：JP15431586

申请日：1986-07-01

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  FUJIKURA YOSHIAKI ,  SEKIGUCHI TAKASHI ,  MASUDA SHINICHI

IPC: C07B61/00 ,  C07D311/76 ,  C07D311/78

公开(公告)号：JPH03261751A

公开(公告)日：1991-11-21

申请号：JP6061290

申请日：1990-03-12

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  TATEZAWA OSAMU ,  YOKOTA YUKINAGA ,  TAKIGAWA HIROBUMI

IPC: A61K8/00 ,  A01N37/20 ,  A61K8/40 ,  A61Q5/12 ,  C07C233/47 ,  C09K15/22

Abstract: NEW MATERIAL:A quaternary ammonium salt shown by formula I [R is n-or iso-1-21C alkyl or alkenyl; R , R , R and R are 1-6C alkyl; R is n-, iso-or cyclic 1-22C alkyl, alkenyl or aralkyl which may contain substituent group; n is 1-6; X(-) is anion]. EXAMPLE:3-{-[3-Ethoxy-1-(ethoxycarbonyl)-3-oxopropyl](1-oxododecyl)ami no}-N,N, N-trimethyl-1-propanaminium chloride. USE:A disinfectant having low irritation, softener, rinse base, antistatic agent, etc. PREPARATION:A diamine shown by formula II is reacted with a maleic acid dialkyl ester shown by formula III to form a compound shown by formula IV, which is then reacted with a compound shown by formula V to give a compound shown by formula VI. This compound is reacted with a compound shown by formula VII (Y is halogen or alkyl sulfate residue) to give a compound shown by formula I.

公开(公告)号：JPH03220170A

公开(公告)日：1991-09-27

申请号：JP1555890

申请日：1990-01-25

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  KOIKE TOYOMI ,  YOKOTA YUKINAGA ,  SUGITA JUNICHI

IPC: B01F17/24 ,  B01F17/38 ,  C07C303/22 ,  C07C309/15 ,  C11D1/28

Abstract: NEW MATERIAL:A compound expressed by formula I (R is 1-21C alkyl or alkenyl; R' is 3-22C alkyl, 1-22C alkenyl or hydroxyalkyl or 2-25C alkoxyalkyl; M is H, alkali metal, alkaline earth metal or ammonium compound) or salt thereof. EXAMPLE:Sodium 3-[N-lauroyl-N-(2'-hydroxypropyl)amino]-2-hydroxyl-1- propanesulfonate. USE:A surfactant, mild to the skin, good in biodegradability, improved in foaming power and hard water resistance and excellent in solubility in water. PREPARATION:A compound expressed by formula II (M' is alkali metal; X is halogen) is allowed to react with a primary amine expressed by the formula R'-NH2 and the resultant compound is then acylated with an acyl chloride in the presence of an alkali (e.g. NaOH) at 0-60 deg.C to afford the compound expressed by formula I.

公开(公告)号：JPH0363256A

公开(公告)日：1991-03-19

申请号：JP19983689

申请日：1989-08-01

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  KOIKE TOYOMI ,  YOKOTA YUKINAGA ,  TAKIGAWA HIROBUMI

IPC: A01N37/34 ,  C07C253/30 ,  C07C255/29

Abstract: NEW MATERIAL:A 3-[(cyanoethyl) (1-oxoalkyl)amino]-N,N,N-trialkyl-1 propanamium salt of formula I (R' is 1-21C alkyl or alkenyl; R and R are each 1-6C alkyl; R is 1-22C alkyl or arylalkyl; X is anion). EXAMPLE:3-[(cyanoethyl) (1-oxododecyl)amino]-N,N,N-trimethyl-1propanaminium chloride. USE:Useful as a low-irritant bactericide. Also having effects as a surfactant. Excellent in foaming power and good in biodegradability and degradability in water, thus finding wide applications in various fields. PREPARATION:The objective compound can be obtained by quaternarizing an alkyl halide to a 3-[N-acyl-N(dialkylaminopropyl)amino]propionitrile of formula II.

公开(公告)号：JPH0344337A

公开(公告)日：1991-02-26

申请号：JP17884089

申请日：1989-07-11

Applicant: KAO CORP

Inventor： SEKIGUCHI TAKASHI ,  NAKAGAWA SHOJI ,  FUJIKURA YOSHIAKI

IPC: C07C2/70 ,  C07B61/00 ,  C07C13/465

Abstract: PURPOSE:To economically obtain a polyalkylindane useful as an intermediate for musk-based perfume by effectively utilizing an alkene dimer treated as a by-product in a conventional procedure by reacting an alkene dimer with alpha-methylstyrene in the presence of an acid catalyst. CONSTITUTION:An alkene dimer shown by formula I to formula Ill or a mixture thereof is reacted with alpha-methylstyrene in the presence of an acid catalyst, preferably a mixed acid prepared by blending sulfuric acid with acetic acid in the ratio of 1 sulfuric acid and 0.1-2.0, preferably 0.5-1.5, more preferably 0.8-1.2 acetic acid by weight at 40-120 deg.C, preferably 60-120 deg.C to economically give the objective compound shown by formula IV (R and R are H or methyl; R and R are methyl or ethyl) by effectively utilizing the alkene dimer, which has been produced in a large amount as a by-product by a conventional method and abandoned, as a raw material.

公开(公告)号：JPH0931003A

公开(公告)日：1997-02-04

申请号：JP20385995

申请日：1995-07-17

Applicant: KAO CORP

Inventor： SAWADA HIROKI ,  NAKAGAWA SHOJI ,  HAGIWARA TOSHIYA ,  TOGASHI HIROYASU

IPC: C07D317/22 ,  C07C41/06 ,  C07C43/04 ,  C07C43/11 ,  C07D317/72 ,  C07D319/06 ,  C07D493/04 ,  C08G2/00

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound containing both polyoxyalkyleneoxymethylene and cyclic acetal units in the molecule, high in linear orientation of the alkylene oxide, excellent in the adsorption to to-be- lubricated surface and lubricity, thus useful as e.g. a refrigerating machine oil. SOLUTION: This compound has e.g. a structure of formula I [R1 is H, a 1-21C (branched) alkyl (A), etc.; R2 is such that when R1 is H, it is a 3-21C branched alkyl, while, when R1 is A, it is A, etc.; R3 is H or a 1-8C (branched) alkyl; X is a 2-4C (branched) alkylene; k1 is 0-5; p1 is 0-2; m1 is 0 or 1; k1 , p1 and m1 satisfy the relationship: k1 +(m1 +2)p1 =5; a1 and b1 are each 0-20, satisfying the relationship: 0

公开(公告)号：JPH083590A

公开(公告)日：1996-01-09

申请号：JP13846694

申请日：1994-06-21

Applicant: KAO CORP

Inventor： JIN NORIKAZU ,  YAMAGUCHI OSAMU ,  INOUE TAKUMI ,  TSUKUDA KAZUKUNI ,  NAKAGAWA SHOJI

IPC: C11D3/20 ,  C11D7/26

Abstract: PURPOSE:To obtain the composition capable of sufficiently cleaning not only a common stain but also an oil stain having a high degree of denaturation by adding a surfactant, a builder and water to a prescribed acetal derivative. CONSTITUTION:This cleaning agent composition for hard surface contains (A) an acetal derivative of formula I (R and R are independently each H, a 1-5C alkyl, alkynyl, etc.; A is a 2-4C alkylene; (n) is 0-10), (B) a surfactant, (C) a builder and (D) water. The component A is synthesized by acetalizing or ketalizing with an aldehyde or a ketone with a glycerol in the presence of an acid catalyst by a scheme of formula II. The cleaning agent composition for hard surface suitable for a cleaning agent for kitchens is obtained.

公开(公告)号：JPH073289A

公开(公告)日：1995-01-06

申请号：JP14775893

申请日：1993-06-18

Applicant: KAO CORP

Inventor： INOUE TAKUMI ,  YAMAGUCHI OSAMU ,  NAKAGAWA SHOJI ,  TSUKUDA KAZUKUNI

IPC: C11D3/20

Abstract: PURPOSE:To obtain the subject composition containing a specific glyceryl ether, a surfactant, a builder and water respectively in a specified amount and exhibiting a high detergency on a hard surface of a kitchen, a bathroom, a wall, a floor, etc., regardless of the kind or the degree of a stain. CONSTITUTION:This composition is composed of (A) 0.01 to 50wt.% glyceryl ether derivative (preferably isopropyl glyceryl ether, etc.) of the formula (R is a 1 to 7C straight- or branched-chain alkyl, alkenyl, phenyl, etc.), (B) 0 to 50wt.% surfactant (preferably an alkylbenzenesulfonic acid salt, etc.), (C) 0 to 50wt.% builder (preferably ethylenediaminetetraacetic acid, etc.) and (D) water as the remainder component. Both the components (B) and (C) are not 0wt.% and the total amount of the components (B) and (C) is 0.01 to 70wt.%. In addition, the component (A) is obtained, e.g. by conducting an etherification reaction between an alcohol compound and 1-chloro-2,3-epoxypropane in the presence of a Lewis acid catalyst, condensing the resultant etherified compound, subsequently hydrolyzing it and opening the epoxy ring of the reaction product.

公开(公告)号：JPH06192194A

公开(公告)日：1994-07-12

申请号：JP34681192

申请日：1992-12-25

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  MATSUMOTO YASUMASA ,  KUSUMI TOMOKATSU

IPC: C07C231/02 ,  C07C231/10 ,  C07C233/18 ,  C07D263/14

Abstract: PURPOSE:To produce the subject compound useful for cosmetic base materials, etc., without causing dangers such as environmental pollution and fire by reacting a specific branched fatty acid with tris(hydroxymethyl)aminomethane and subsequently hydrolyzing the reactional product in the absence of a solvent in a specific volume of water at a specified temperature. CONSTITUTION:A branched fatty acid of formula I ((m), (n) are integers of 0-20, but (m+n)= 1-20)(preferably isostearic acid) is reacted with tris(hydroxymethyl)aminomethane at 160 deg.C for 6hrs to produce an oxazoline compound of formula II [e.g. 2-heptadecyl-4,4-bis(hydroxymethyl)-2-oxazoline]. The oxazoline compound is mixed with water in an amount of 1-3 time moles, and hydrolyzed in the absence of a solvent at 50-150 deg.C to simply and inexpensively the objective fatty acid [e.g. N-tris(hydroxymethyl)methyl-isostearic acid amide] of formula III useful for cosmetic base materials, emusifiers, lubricants, etc.

公开(公告)号：JPH0578294A

公开(公告)日：1993-03-30

申请号：JP23960591

申请日：1991-09-19

Applicant: KAO CORP

Inventor： NAKAGAWA SHOJI ,  OCHIAI TATSUSHI ,  YAHAGI KAZUYUKI

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/42 ,  A61K8/49 ,  A61Q5/00 ,  A61Q19/00 ,  C07C231/02 ,  C07C231/10 ,  C07C233/18 ,  C07D263/14

Abstract: PURPOSE:To obtain the new subject compound having extremely excellent lubricating properties, exhibiting excellent compatibility with most of solvents, capable of uniformly dispersing in water, useful for a base, emulsifier, etc., for hair cosmetic and skin cosmetic and capable of simply and inexpensively synthesizing. CONSTITUTION:A branched fatty acid amide of formula I (R and R are 2-24C straight chain alkyl, with the provide so that total carbon number of R and R is 4-26), e.g. N-tris(hydroxymethyl)methyl-alpha-octylarachidic amide. The compound is obtained by reacting a branched fatty acid of formula II with an equimolar tris(hydroxymethyl)aminomethane of formula III to afford an oxazoline derivative of formula IV and then hydrolyzing the oxazoline derivative. The reaction of the compound of formula II with the compound formula III is preferably carried out at 50-200 deg.C for 1-130hr while removing produced water. The hydrolysis reaction is preferably carried out in water or a mixed solution of water and 1-6C alcohol at 70-120 deg.C. Furthermore, the intermediate of formula IV is a new compound.