公开(公告)号：US09839374B2

公开(公告)日：2017-12-12

申请号：US13243362

申请日：2011-09-23

Applicant: Martin Roche ,  Marc Boillot ,  Marc Stein

Inventor： Martin Roche ,  Marc Boillot ,  Marc Stein

IPC: A61B5/103 ,  A61B5/107 ,  A61B5/00 ,  A61F2/46 ,  A61F2/44 ,  A61F2/28 ,  A61F2/30

CPC classification number: A61B5/103 ,  A61B5/1036 ,  A61B5/1071 ,  A61B5/4566 ,  A61B5/686 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30011 ,  A61F2002/3085 ,  A61F2002/4475 ,  A61F2310/00023

Abstract: A load balance and alignment system is provided to assess load forces on the vertebra in conjunction with overall spinal alignment. The system includes a spine instrument having an electronic assembly and a sensorized head. The sensorized head can be inserted between vertebra and report vertebral conditions such as force, pressure, orientation and edge loading. A GUI is therewith provided to show where the spine instrument is positioned relative to vertebral bodies as the instrument is placed in the inter-vertebral space. The system can report optimal prosthetic size and placement in view of the sensed load and location parameters including optional orientation, rotation and insertion angle along a determined insert trajectory.

公开(公告)号：US09592010B2

公开(公告)日：2017-03-14

申请号：US12825931

申请日：2010-06-29

Applicant: Marc Stein

Inventor： Marc Stein

IPC: A61B5/05 ,  A61B5/00 ,  A61B8/15

CPC classification number: A61B5/6878 ,  A61B5/4509 ,  A61B5/4528 ,  A61B5/6846 ,  A61B5/7239 ,  A61B8/15 ,  Y10T307/615

Abstract: A dual-mode closed-loop measurement system (100) for capturing a transit time, phase, or frequency of energy waves propagating through a medium (122) is disclosed. A first device comprises an inductor drive circuit (102), an inductor (104), a transducer (106), and a filter (110). A second circuit comprises an inductor (114) and a transducer (116). A parameter to be measured is applied to the medium (122). The medium (122) is coupled between the first device and the second device. The first device initiates the transmit inductor (104) to query via inductive coupling to a receive inductor (114) on the second device via a first path. The inductor (114) triggers a transducer (116) on the second device to emit an energy wave that is propagated in the medium (122) and detected by the first device. The transit time of energy waves is affected by the parameter by known relationship.

Abstract translation: 公开了一种用于捕获通过介质（122）传播的能量波的传播时间，相位或频率的双模式闭环测量系统（100）。 第一装置包括电感器驱动电路（102），电感器（104），换能器（106）和滤波器（110）。 第二电路包括电感器（114）和换能器（116）。 要测量的参数被应用于介质（122）。 介质（122）耦合在第一装置和第二装置之间。 第一设备启动发射电感器（104），以通过经由第一路径的电感耦合到第二设备上的接收电感器（114）来查询。 电感器（114）触发第二装置上的换能器（116）以发射在介质（122）中传播并由第一装置检测的能量波。 能量波的传播时间受到已知关系的参数的影响。

公开(公告)号：US09332943B2

公开(公告)日：2016-05-10

申请号：US13244211

申请日：2011-09-23

Applicant: Marc Stein ,  Andrew P. Miller ,  Jason Addink ,  Andrew U. Chase

Inventor： Marc Stein ,  Andrew P. Miller ,  Jason Addink ,  Andrew U. Chase

IPC: A61B5/00 ,  A61B5/103 ,  A61F2/38 ,  A61F2/46 ,  A61F2/30

CPC classification number: A61B5/6878 ,  A61B5/0031 ,  A61B5/1036 ,  A61B5/6882 ,  A61F2/3859 ,  A61F2/389 ,  A61F2/4657 ,  A61F2002/30565 ,  A61F2002/30589 ,  A61F2002/30607 ,  A61F2002/30616 ,  A61F2002/30668 ,  A61F2002/3067 ,  A61F2002/30672 ,  A61F2002/30772 ,  A61F2002/3895 ,  A61F2002/4666

Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert can be less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The insert includes a flexible articular surface. Flexible articular surface transfers loading to sensors internal to the insert.

Abstract translation: 至少一个实施例涉及用于测量肌肉 - 骨骼系统的参数的插入件。 插入可以是临时的或永久的。 在一个实施例中，插入件是用于膝盖的单个隔室的假体部件。 插入件包括分别具有关节表面和承载表面的支撑结构和支撑结构。 刀片的高度可以小于10毫米。 当支撑结构耦合在一起以容纳电子电路，传感器和电源时，形成至少一个内部空腔。 插入物包括柔性关节表面。 弹性关节表面传递加载到插入物内部的传感器。

公开(公告)号：US08689647B2

公开(公告)日：2014-04-08

申请号：US13539476

申请日：2012-07-01

Applicant: Marc Stein

Inventor： Marc Stein

IPC: G01L1/04

CPC classification number: A61B5/6878 ,  A61B5/4509 ,  A61B5/4528 ,  A61B5/6846 ,  A61B5/7239 ,  A61B8/15 ,  Y10T307/615

Abstract: A sensing insert device (100) is disclosed for measuring a parameter of the muscular-skeletal system. The sensing insert device (100) can be temporary or permanent. Used intra-operatively, the sensing insert device (100) comprises an insert dock (202) and a sensing module (200). The sensing module (200) is a self-contained encapsulated measurement device having at least one contacting surface that couples to the muscular-skeletal system. The sensing module (200) comprises one or more sensing assemblages, electronic circuitry (307), an antenna (2302), and communication circuitry (320). The sensing assemblages are between a top plate (1502) and a bottom plate (1504) in a sensing platform (121). The sensing assemblages comprise a load disc (2004) and a piezo-resistive sensor (2002) to measure the parameter. An elastic support structure or springs (1108) is coupled between the top plate (1502) and the bottom plate (1504) to prevent cantilevering of a surface.

Abstract translation: 公开了一种用于测量肌肉 - 骨骼系统的参数的感测插入装置（100）。 感测插入装置（100）可以是暂时的或永久的。 在操作中使用的感测插入装置（100）包括插入坞（202）和感测模块（200）。 感测模块​​（200）是独立的封装测量装置，其具有耦合到肌肉 - 骨骼系统的至少一个接触表面。 感测模块​​（200）包括一个或多个感测组件，电子电路（307），天线（2302）和通信电路（320）。 感测组件位于感测平台（121）中的顶板（1502）和底板（1504）之间。 感测组件包括负载盘（2004）和压阻传感器（2002）以测量参数。 弹性支撑结构或弹簧（1108）联接在顶板（1502）和底板（1504）之间，以防止表面悬臂。

公开(公告)号：US08539830B2

公开(公告)日：2013-09-24

申请号：US13406524

申请日：2012-02-27

Applicant: Marc Stein

Inventor： Marc Stein

IPC: A61B5/22

CPC classification number: A61B5/4528 ,  A61B5/4509 ,  A61B5/6846

Abstract: A measurement system for capturing a transit time, phase, or frequency of energy waves propagating through a propagation medium is disclosed. The measurement system comprises a compressible waveguide (403), ultrasonic transducers (405, 406), and circuitry to sustain energy wave propagation in the waveguide (403). The circuitry includes a propagation tuned oscillator (404), a digital counter (409), a pulse generator (410), a phase detector (414), a counter (420), a digital timer (422), and a data register (424). The measurement system employs a continuous mode (CM), pulse mode, or pulse-echo mode of operation to evaluate propagation characteristics of continuous ultrasonic waves in the waveguide by way of closed-loop feedback to determine levels of applied forces on the waveguide.

Abstract translation: 公开了一种用于捕获通过传播介质传播的能量波的传播时间，相位或频率的测量系统。 测量系统包括可压缩波导（403），超声波换能器（405,406）和用于维持波导（403）中的能量波传播的电路。 电路包括传播调谐振荡器（404），数字计数器（409），脉冲发生器（410），相位检测器（414），计数器（420），数字定时器（422）和数据寄存器 424）。 测量系统采用连续模式（CM），脉冲模式或脉冲回波模式，通过闭环反馈来评估波导中连续超声波的传播特性，以确定波导上施加的力的水平。

公开(公告)号：US08516907B2

公开(公告)日：2013-08-27

申请号：US12825753

申请日：2010-06-29

Applicant: Marc Stein ,  James Ellis

Inventor： Marc Stein ,  James Ellis

IPC: G01L1/04

CPC classification number: A61B5/6878 ,  A61B5/4509 ,  A61B5/4528 ,  A61B5/6846 ,  A61B5/7239 ,  A61B8/15 ,  Y10T307/615

Abstract: A load sensing platform (121) is disclosed for capturing a transit time, phase, or frequency of energy waves propagating through a medium that measures a parameter of the muscular-skeletal system. The load sensing platform (121) comprises a sensing assemblage (1), substrates (702, 704, and 706), springs (315), spring posts (708), and spring retainers (710). The sensing assemblage (1) comprises a stack of a transducer (5), waveguide (3), and transducer (6). A parameter is applied to the contact surfaces (8) of the load sensing platform (121). The sensing assemblage (1) measures changes in dimension due to the parameter. Position of the applied parameter can be measured by using more than one sensing assemblage (1). The springs (315) couple to the substrates (702, 704) providing mechanical support and to prevent cantilevering. The spring posts (708) and spring retainers (710) maintain the springs (315) at predetermined locations in the load sensing platform (121).

Abstract translation: 公开了负载感测平台（121），用于捕获通过测量肌肉 - 骨骼系统的参数的介质传播的能量波的渡越时间，相位或频率。 负载感测平台（121）包括感测组件（1），基底（702,704和706），弹簧（315），弹簧柱（708）和弹簧保持器（710）。 感测组件（1）包括传感器（5），波导（3）和换能器（6）的堆叠。 将参数应用于负载感测平台（121）的接触表面（8）。 感测组合（1）由于参数而测量尺寸变化。 应用参数的位置可以通过使用多个传感组件（1）来测量。 弹簧（315）耦合到提供机械支撑并防止悬臂的基板（702,704）。 弹簧柱（708）和弹簧保持器（710）将弹簧（315）保持在负载感测平台（121）中的预定位置处。

公开(公告)号：US08427176B2

公开(公告)日：2013-04-23

申请号：US12748078

申请日：2010-03-26

Applicant: Marc Stein

Inventor： Marc Stein

IPC: G01R27/04 ,  G01R27/32

CPC classification number: G01L1/255 ,  G01D5/48 ,  G01L1/165 ,  G01L5/16 ,  G01L5/167

Abstract: At least one embodiment is directed to a sensor for measuring a parameter. A signal path of the system comprises an amplifier (612), a sensor element, and an amplifier (620). The sensor element comprises a transducer (4), a waveguide (5), and a transducer (30). A parameter such as force or pressure applied to the sensor element can change the length of waveguide (5). A pulsed energy wave is emitted by the transducer (4) into the waveguide (5) at a first location. The transducer (30) is responsive pulsed energy waves at a second location of the waveguide (5). The transit time of each pulsed energy wave is measured. The transit time corresponds to the pressure or force applied to the sensor element.

Abstract translation: 至少一个实施例涉及用于测量参数的传感器。 系统的信号路径包括放大器（612），传感器元件和放大器（620）。 传感器元件包括换能器（4），波导（5）和换能器（30）。 诸如施加到传感器元件的力或压力的参数可以改变波导（5）的长度。 在第一位置处，换能器（4）将脉冲能量波发射到波导（5）中。 换能器（30）在波导（5）的第二位置处响应脉冲能量波。 测量每个脉冲能量波的渡越时间。 通过时间对应于施加到传感器元件的压力或力。

公开(公告)号：US20130079674A1

公开(公告)日：2013-03-28

申请号：US13244227

申请日：2011-09-23

Applicant: Marc Stein ,  Andrew P. Miller ,  Jason Addink ,  Andrew U. Chase

Inventor： Marc Stein ,  Andrew P. Miller ,  Jason Addink ,  Andrew U. Chase

IPC: A61B5/103

CPC classification number: A61B5/4585 ,  A61B5/0031 ,  A61B5/11 ,  A61B5/686 ,  A61B5/6882 ,  A61B2560/0406 ,  A61B2562/24 ,  A61F2/4657 ,  A61F2/4684 ,  A61F2002/3895 ,  A61F2002/4666

Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The internal cavity is isolated from the external environment and can be hermetically sealed. The exterior surfaces of the support structure and the support structure are sterilized.

Abstract translation: 至少一个实施例涉及用于测量肌肉 - 骨骼系统的参数的插入件。 插入可以是临时的或永久的。 在一个实施例中，插入件是用于膝盖的单个隔室的假体部件。 插入件包括分别具有关节表面和承载表面的支撑结构和支撑结构。 刀片的高度小于10毫米。 当支撑结构耦合在一起以容纳电子电路，传感器和电源时，形成至少一个内部空腔。 内部空腔与外部环境隔离，可以密封。 支撑结构和支撑结构的外表面被灭菌。

公开(公告)号：US20120226359A1

公开(公告)日：2012-09-06

申请号：US13406515

申请日：2012-02-27

Applicant: Marc Stein ,  Andrew Chase

Inventor： Marc Stein ,  Andrew Chase

IPC: A61F2/38 ,  A61B5/11

CPC classification number: A61F2/4657 ,  A61B5/4509 ,  A61B5/4528 ,  A61B5/6846

Abstract: A prosthetic component suitable for long-term implantation is provided. The prosthetic component measures a parameter of the muscular-skeletal system is disclosed. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. The sensor couples to the support surface of the first structure. The first and second structure are coupled together housing the at least one sensor. The first and second structures comprises steel, titanium, cobalt or an alloy thereof. At least one of the first or second structures is coupled to ground to shield the sensor from parasitic coupling. The at least one sensor can be a pressure sensor for measuring load and position of load.

Abstract translation: 提供了适合于长期植入的假体部件。 公开了假肢部件测量肌肉骨骼系统的参数。 假体部件包括具有至少一个支撑表面的第一结构，具有被配置为耦合到骨骼的至少一个特征的第二结构以及至少一个传感器。 电子电路和传感器密封在假体部件内。 传感器耦合到第一结构的支撑表面。 第一和第二结构联接在一起，容纳至少一个传感器。 第一和第二结构包括钢，钛，钴或其合金。 第一或第二结构中的至少一个耦合到地以屏蔽传感器与寄生耦合。 至少一个传感器可以是用于测量负载和负载位置的压力传感器。

公开(公告)号：US20120220839A1

公开(公告)日：2012-08-30

申请号：US13406523

申请日：2012-02-27

Applicant: Marc Stein ,  Andrew Chase

Inventor： Marc Stein ,  Andrew Chase

IPC: A61B5/00

CPC classification number: A61B5/14507 ,  A61B5/1455 ,  A61B5/4509 ,  A61B5/4528 ,  A61B5/6846

Abstract: A prosthetic component suitable for long-term implantation is provided. The prosthetic component includes electronic circuitry and sensors to measure a parameter of the muscular-skeletal system. The prosthetic component comprises a first structure having at least one support surface, a second structure having at least one feature configured to couple to bone, and at least one sensor. The electronic circuitry and sensors are hermetically sealed within the prosthetic component. One or more sensors can be used to monitor synovial fluid in proximity to the joint to determine joint health. The prosthetic component includes a transmissive region. One or more optical sensors are mounted in proximity to the transmissive region. Periodic measurements of the synovial fluid are measured through the transmissive region. The measurements can include color and turbidity of the synovial fluid. The color and turbidity data can be compared against known data to determine joint status.

Abstract translation: 提供了适合于长期植入的假体部件。 假肢部件包括用于测量肌肉骨骼系统的参数的电子电路和传感器。 假体部件包括具有至少一个支撑表面的第一结构，具有被配置为耦合到骨骼的至少一个特征的第二结构以及至少一个传感器。 电子电路和传感器密封在假体部件内。 一个或多个传感器可用于监测靠近关节的滑液，以确定关节的健康状况。 假体部件包括透射区域。 一个或多个光学传感器安装在透射区域附近。 通过透射区域测量滑液的周期性测量。 测量可以包括滑液的颜色和浊度。 可以将颜色和浊度数据与已知数据进行比较以确定联合状态。