Abstract:
A vaccine for the immunization of domestic fowl, such as turkeys and chickens, against E. coli infections (Colibacillosis) is disclosed which contains an effective amount of a live temperature sensitive mutant of E. coli dispersed in a physiologically acceptable, non-toxic liquid vehicle. The E. coli mutant disclosed exhibits growth at 32 DEG C but not at 41 DEG C and has a reversion frequency of less than about 1 x 10 .
Abstract:
A microsensor or micromechanical device based upon the piezoelectric properties of thin film lead zirconate titanate (PZT) with a thickness of between 0.1 and 5 microns. The thin film PZT (11) is sandwiched between first and second electrodes (10, 12) which are provided with electrical connection means (14, 15) for electrically connecting the electrodes to a voltage sensor or voltage source (16). The invention also relates to a method for making such microsensor or micromechanical device.
Abstract:
Pokeweed antiviral protein (PAP) - monoclonal antibody conjugates capable of inhibiting virus replication in mammalian cells without detectable cytotoxicity are provided.
Abstract:
A particle measurement apparatus (10) for obtaining accurate information relating to airborne particles in a gas under vacuum from a process chamber (12) including a sampling chamber (14) which can be subjected to a very strong vacuum (20) and used for obtaining a sample of the gas in the process chamber (12). The interior of the sampling chamber (14) is first flushed with very clean purge gas (30), and subsequently opened to the process vacuum chamber (12) which is to be sampled so that a sample of the atmosphere of gas from the process vacuum chamber (12) is held in the sampling chamber (14). The sampling chamber (14) is sealed from the process chamber (12) and the sample is brought to atmospheric pressure by adding a particle-free purified gas. The sample is then flushed from the sampling chamber (14) and passed through a particle counter (40). Calculations can then be made to determine the original particle concentration in the process vacuum chamber (12) based on the measured particle concentration from the sample of the sampling chamber (14). By having a series of valves (V1-V6) operated in a selected sequence, a very accurate measurement of particles down to as small as .01 microns can be measured, and the system can be used to measure particles in chambers (12) under from about one atmosphere to approximately .001 atmosphere.
Abstract:
The present invention provides a method of depositing passivation layers on the surface of a superconducting ceramic oxide comprising employing the techniques of activated chemical vapor deposition and molecular beam deposition to apply a layer of an oxide of Al, Bi, Si or Al-W, or a layer of CaF2 to the surface.
Abstract:
A method for diagnosing, treating and monitoring hypertension uses the parameter C2 (i.e. distal vascular compliance) of the modified Windkessel model as an indication of the hypertensive disease condition. Apparatus for determining the parameter C2 of the modified Windkessel model includes means for obtaining a pressure pulse contour and a cardiac output value and for determining the model parameters.
Abstract:
A cleaning system which utilizes surface tension forces (4) and phase changes. The surface (21) to be cleaned is submerged within a vessel (30), and the vessel pressure is increased. Rapid depressurization causes bubbles (12) to form around undesired particulate matter (13) on the surface (14) of the article, the bubbles (12) rising to the surface of the liquid (27), thereby cleaning the article. A second embodiment applies a cleaning fluid (52) to the surface of the article (49) and freezes the fluid (52), thereby reducing the adhesion force between the surface and the particulates. The surface is subsequently heated, and the particulate matter is removed through the medium of the cleaning fluid (52).
Abstract:
The present invention provides a liquid infusate for the chronic vascular infusion of a hydrophobic biologically-active compound, such as cyclosporin, comprising a solution of a therapeutically-effective amount of the biologically-active compound in a mixture of about 10-80% glycerol and about 90-20% ethanol, by volume.
Abstract:
A method is disclosed for the prevention and alleviation of pathologic changes in the eye such as diabetic retinopathy or senile macular degeneration. The claimed method involves the parenteral administration of anisodamine in an amount effective for preventing or alleviating these pathologic changes.
Abstract:
A new family of memory cells and digital-logic gates use an enhancement-mode driver (20), a voltage-level shifter (16), and a current regulator (18) to provide improved noise margins and large logic swings. The voltage-level shifter (16) and the current regulator (18) are connected in series between an input (12) and the control electrode of the driver (20). The voltage-level shifter (16) establishes a voltage drop which is independent of current, while the current regulator (18) establishes a constant current in the series path to the control electrode which is independent of voltage. The driver (20) is an enhancement-mode device, such as a JFET, MESFET, or BJT.