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公开(公告)号：ZA200709480B
公开(公告)日：2010-07-28
申请号：ZA200709480
申请日：2007-11-02
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , GRAHAM KEVIN , HOFFMAN KELLY SUE , LAWSON ALASTAIR , POPPLEWELL ANDY , WINKLER DAVID G , ROBINSON MARTYN KIM , HENRY ALISTAIR JAMES , LATHAM JOHN , LU HSIENG SEN , SHEN WENYAN , WINTERS AARON GEORGE
IPC: C07K20060101
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：NO20076046L
公开(公告)日：2008-01-30
申请号：NO20076046
申请日：2007-11-23
Applicant: UCB PHARMA SA
Inventor： LATHAM JOHN , PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K14/51 , C07K14/435 , C07K16/18 , C07K16/28
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：CA2607197A1
公开(公告)日：2006-11-09
申请号：CA2607197
申请日：2006-04-28
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LATHAM JOHN , HOFFMANN KELLY SUE , WINKLER DAVID , LAWSON ALASTAIR , LU HSIENG SEN , HENRY ALISTAIR JAMES , SHEN WENYAN , ROBINSON MARTYN KIM , GRAHAM KEVIN , PASZTY CHRISTOPHER , POPPLEWELL ANDY
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin-binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：RS62685B1
公开(公告)日：2021-12-31
申请号：RSP20211488
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
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公开(公告)号：UA123695C2
公开(公告)日：2021-05-19
申请号：UAA201202580
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Винахідналежитьдополіпептиду, щоявляєсобоюепітопбілкасклеростинулюдини, способуодержанняантитіла, якезв’язуєвказанийепітоп, антитіла, здатногозв'язуватисяізвказанимепітопомсклеростину, виділеногополінуклеотиду, клонуючогоабоекспресуючоговектора, клітини-хазяїна, фармацевтичноїкомпозиції, застосуванняфармацевтичноїкомпозиціїдлялікуванняпорушення, опосередкованогопідвищенимрівнемсклеростинутадіагностичногонабору, щоміститьзазначенеантитіло.
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Patent Agency Ranking
公开(公告)号：ES2689143T3
公开(公告)日：2018-11-08
申请号：ES10008795
申请日：2006-04-28
Applicant: UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTY KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Un anticuerpo de unión a esclerostina que comprende las siguientes secuencias de CDR: CDR-H1: DYIMH (SEQ ID NO: 269); CDR-H2: YINPYNDDTEYNEKFKG (SEQ ID NO: 270); CDR-H3: SIYYYDAPFAY (SEQ ID NO: 271); CDR-L1: RASQDISSYLN (SEC ID No: 239); CDR-L2: STSRLNS (SEQ ID NO: 240); y CDR-L3: QQDIKHPT (SEQ ID NO: 241).
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公开(公告)号：AU2012238247B2
公开(公告)日：2016-06-16
申请号：AU2012238247
申请日：2012-10-08
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LAWSON ALASTAIR , HENRY ALISTAIR JAMES , POPPLEWELL ANDY , PASZTY CHRISTOPHER , SHEN WENYAN , LU HSIENG SEN , LATHAM JOHN , HOFFMANN KELLY SUE , GRAHAM KEVIN , ROBINSON MARTYN KIM , WINKLER DAVID
Abstract: C:\NRPorbl\DCCSZPWA6573 I DOC.4/10/2012 Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. 4v Lu L % 6 Iii cc ~ O O. . .U te,, Lo~ .CD C; L 0ZDB aweI
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公开(公告)号：GEP20166454B
公开(公告)日：2016-04-11
申请号：GEAP2006012335
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: An invention relates to antibodies binding sclerostin epitopes, which crossly block Ab-C, Ab-D, Ab-13 or Ab-14 binding with sclerostin sequ¬ences SEQ ID NO: 1. Said antibodies are applied at the treatment of diseases related to abnormalities in bone mineral density and of bone mass.
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公开(公告)号：GEP20125594B
公开(公告)日：2012-08-10
申请号：GEAP2006010403
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWEL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: There are represented sclerostin binding sequences or amino acid sequences determining segments complementarity in (CDR) antibodies blocking binding and isolated coding polynucleotide sequences thereof, pharmaceutical compositions containing said antibodies and their usage at the treatment of diseases associated with sclerostin, particularly, with bone mineralization related diseases.
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公开(公告)号：MA29528B1
公开(公告)日：2008-06-02
申请号：MA30433
申请日：2007-11-29
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: L'INVENTION CONCERNE DES COMPOSITIONS ET DES PROCÉDÉS AYANT TRAIT AUX ÉPITOPES DE LA PROTÉINE SCLÉROSTINE, ET DES AGENTS DE FIXATION À LA SCLÉROSTINE TELS QUE DES ANTICORPS POUVANT SE FIXER À LA SCLÉROSTINE
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