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    用于防止在微阵列扫描中的过分曝光和光泄漏的掩模
    21.
    发明公开
    用于防止在微阵列扫描中的过分曝光和光泄漏的掩模 无效

    公开(公告)号：CN101507256A

    公开(公告)日：2009-08-12

    申请号：CN200680045923.2

    申请日：2006-12-04

    Applicant: 生物辐射实验室股份有限公司

    Inventor： D·Y·楚

    IPC: H04N1/04 ,  G01J1/58 ,  G01N21/63 ,  G02B26/10

    CPC classification number: G01N21/253 ,  G01N2201/0446 ,  G01N2201/1042

    Abstract: 微阵列的扫描是通过能够曝光微阵列上的多个但不是所有位置的掩模来实现的，并且掩模可相对于微阵列移动或者微阵列可相对于掩模移动，或者两者兼之。掩模作为在扫描头的行进处于待机、目标速度时限制对能够照明的微阵列上的微阵列位置的照明的部件是十分有用的，它能够在扫描头轨迹中的一些扫描头加速或者减速的点上阻止光在扫描头和微阵列之间的通过。通过防止光泄漏到与正在扫描的位置相邻的位置上，掩模可以十分有效地减小在微阵列成像中的背景噪声。

    NEPHELOMETRY METHOD AND APPARATUS FOR DETERMINING THE CONCENTRATION OF SUSPENDED PARTICLES IN AN ARRAY OF SAMPLE CONTAINERS
    25.
    发明申请
    NEPHELOMETRY METHOD AND APPARATUS FOR DETERMINING THE CONCENTRATION OF SUSPENDED PARTICLES IN AN ARRAY OF SAMPLE CONTAINERS 审中-公开
    用于确定样品容器的阵列中悬浮颗粒浓度的测定方法和装置

    公开(公告)号：WO2015026794A1

    公开(公告)日：2015-02-26

    申请号：PCT/US2014/051645

    申请日：2014-08-19

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： BERNDT, Klaus, W. ,  HANSEN, Timothy, R.

    IPC: G01N21/49 ,  G01N21/51 ,  G01N15/06 ,  G01N33/483 ,  G01N33/53

    CPC classification number: G01N21/51 ,  G01N15/06 ,  G01N2015/0693 ,  G01N2021/4709 ,  G01N2021/4761 ,  G01N2021/513 ,  G01N2201/0446 ,  G01N2201/062

    Abstract: Described are devices, methods, and systems that are suitable for rapidly and simultaneously determining the concentration of suspended particles in a sample. The devices, methods, and systems allow for the rapid and simultaneous interrogation of a large number of sample wells in a single vessel, for example, samples contained in a two- dimensional array or micro-titer plate, without the need for moving reading heads or moving the sample vessel. The nephelometry system allows the user to rapidly and simultaneously measure the concentration of the particles in numerous samples, adjust the concentration of the particles in the sample with a sample handling system, and re-measure the concentration of the samples in order to achieve a desired concentration.

    Abstract translation: 描述了适于快速并同时确定样品中悬浮颗粒浓度的装置，方法和系统。 装置，方法和系统允许在单个容器中快速和同时询问大量样品孔，例如包含在二维阵列或微滴定板中的样品，而不需要移动读取头 或移动样品容器。 比浊法系统允许用户快速并同时测量多个样品中的颗粒浓度，用样品处理系统调节样品中颗粒的浓度，并重新测量样品的浓度以达到所需的 浓度。

    ILLUMINATION SYSTEMS
    26.
    发明申请
    ILLUMINATION SYSTEMS 审中-公开
    照明系统

    公开(公告)号：WO2014026156A1

    公开(公告)日：2014-02-13

    申请号：PCT/US2013/054413

    申请日：2013-08-09

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： MAHER, Kevin

    IPC: G01N21/64

    CPC classification number: G01N21/6486 ,  G01N21/6452 ,  G01N2021/6463 ,  G01N2201/0446 ,  G01N2201/062 ,  G01N2201/0631

    Abstract: A system (500) for detecting emissions from a sample containing nucleotide molecules contains a sample holder (501), an optical illumination system (612), and an optical sensor (620). The sample holder includes a plurality of spatially separated reaction sites configured to hold a sample containing nucleotide molecules. The optical illumination system comprises a radiant source (610) configured to simultaneously illuminate two or more of the reaction sites. The illumination system includes a homogenizer (112). An output from the homogenizer has less variation in power, energy, irradiance, or intensity than the variation in power, energy, irradiance, or intensity of the source.

    Abstract translation: 用于检测含有核苷酸分子的样品的发射的系统（500）包含样品保持器（501），光学照明系统（612）和光学传感器（620）。 样品架包括多个空间分离的反应位点，其配置成容纳含有核苷酸分子的样品。 光学照明系统包括被配置为同时照亮两个或更多个反应位点的辐射源（610）。 照明系统包括均化器（112）。 来自均化器的输出与功率，能量，辐照度或源的强度的变化相比，功率，能量，辐照度或强度的变化较小。

    INSTRUMENTATION AND METHOD ADAPTED FOR OPTICAL MEASUREMENT OF AN AMPLIFIED LUMINESCENT PROXIMITY HOMOGENEOUS ASSAY
    30.
    发明申请
    INSTRUMENTATION AND METHOD ADAPTED FOR OPTICAL MEASUREMENT OF AN AMPLIFIED LUMINESCENT PROXIMITY HOMOGENEOUS ASSAY 审中-公开
    适用于放大的LUMINESCENT近似均质测定的光学测量的仪器和方法

    公开(公告)号：WO2006027406A1

    公开(公告)日：2006-03-16

    申请号：PCT/FI2004/000525

    申请日：2004-09-10

    Applicant: WALLAC OY ,  KIVELÄ, Petri

    Inventor： KIVELÄ, Petri

    IPC: G01N21/64

    CPC classification number: G01N21/253 ,  G01N21/13 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0446 ,  G01N2201/0453 ,  G01N2201/0826 ,  G01N2201/103

    Abstract: The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by providing an optical measurement instrumentation wherein a sample (281-285) is activated (212AS, 218AS) and the emission is detected (291, 292), wherein between the activation and detection phases of measuring the sample, a shift is made in the relative position between the sample and means (218) directing the activation radiation to the sample as well as in the relative position between the sample and the means (293) receiving the emission radiation from the sample. This can be implemented e.g. by moving (299) the sample assay plate and/or a measuring head between the activation and emission phases of a sample. The invention allows a simultaneous activation of a first sample and detecting emission from a second sample thus enhancing efficiency of the measurement.

    Abstract translation: 本发明一般涉及生物化学实验室仪器领域，用于不同应用样品的测量性质。 微量滴定板和相应的样品支架。 本发明的目的是通过提供一种光学测量仪器实现的，其中样品（281-285）被激活（212AS，218AS）并且检测到发射（291,292），其中在测量样品的激活和检测阶段之间 在样品和将激活辐射指向样品的装置（218）之间的相对位置以及样品和接收来自样品的发射辐射的装置（293）之间的相对位置进行位移。 这可以被实现。 通过在样品的活化和发射阶段之间移动（299）样品测定板和/或测量头。 本发明允许同时激活第一样品并检测来自第二样品的发射，从而提高测量的效率。

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