公开(公告)号：US11953437B2

公开(公告)日：2024-04-09

申请号：US17445880

申请日：2021-08-25

Applicant: SpectraSensors, Inc.

Inventor： Marc Winter ,  Xiang Liu ,  Thomas Wilhelm

IPC: G01N21/64 ,  G01N21/17 ,  G01N21/39

CPC classification number: G01N21/6428 ,  G01N21/1702 ,  G01N21/39 ,  G01N2021/1704 ,  G01N2021/1755 ,  G01N2021/6432 ,  G01N2201/06113 ,  G01N2201/12761

Abstract: The present disclosure relates to a device for measuring a first analyte concentration and a second analyte concentration in a measuring medium, the device including: a sample cell; a first light source unit; a first detector unit; a functional element; a second light source unit; a second detector unit; and a control unit adapted to analyze a detected first light for determining a first value representing the concentration of the first analyte in the measuring medium and adapted to analyze a detected third light for determining a second value representing the concentration of the second analyte in the measuring medium. A method of using the device is also disclosed.

公开(公告)号：US11879765B2

公开(公告)日：2024-01-23

申请号：US16560170

申请日：2019-09-04

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Tobias Nebel ,  Sebastien Tixier ,  Michael Kon Yew Hughes ,  Gertjan Hofman ,  Paul Mounter

IPC: G01B15/02 ,  G01G17/02 ,  G01N21/31 ,  G01N21/3563 ,  G01N21/84 ,  G01N21/17

CPC classification number: G01G17/02 ,  G01N21/3151 ,  G01N21/3563 ,  G01N21/8422 ,  G01N2021/1755 ,  G01N2021/8427 ,  G01N2201/12761

Abstract: A measurement apparatus for weight measuring composite sheet including a sheet material having a second material thereon as a coating and/or as embedded particles therein. The apparatus includes an x-ray sensor for providing an x-ray signal from x-ray irradiating the composite sheet and an infrared (IR) sensor for providing an IR signal from IR irradiating the composite sheet. A computing device is coupled to receive the x-ray signal and the IR signal that includes a processor having an associated memory for implementing an algorithm, where the algorithm uses the x-ray signal and the IR signal to compute a plurality of weights selected from a weight of the sheet material, a weight of the second material, and a total weight of the composite sheet.

公开(公告)号：US11662316B2

公开(公告)日：2023-05-30

申请号：US17058091

申请日：2019-05-30

Applicant: Sony Corporation

Inventor： Hirokazu Tatsuta ,  Gakuji Hashimoto ,  Tetsuro Kuwayama

IPC: G01N21/64 ,  G02B21/00 ,  G02B21/16 ,  G02B21/36

CPC classification number: G01N21/6458 ,  G02B21/0064 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/367 ,  G01N2021/6419 ,  G01N2021/6423 ,  G01N2201/12761

Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.

公开(公告)号：US20180259453A1

公开(公告)日：2018-09-13

申请号：US15975686

申请日：2018-05-09

Applicant: Quidel Corporation

Inventor： David Dickson Booker ,  Jhobe Steadman

IPC: G01N21/64 ,  G01N21/27 ,  G01N33/543

CPC classification number: G01N21/645 ,  G01N21/274 ,  G01N21/278 ,  G01N33/54386 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/10 ,  G01N2201/12746 ,  G01N2201/12753 ,  G01N2201/12761

Abstract: Disclosed herein is a method for improving the precision of a test result from an instrument with an optical system that detects a signal. The method comprises including in the instrument a normalization target disposed directly or indirectly in the optical path of the optical system. Also disclosed are instruments comprising a normalization target, and systems comprising such an instrument and a test device that receives a sample suspected of containing an analyte.

公开(公告)号：US4938602A

公开(公告)日：1990-07-03

申请号：US329293

申请日：1989-03-27

Applicant: Joe T. May ,  Edward A. Casacia

Inventor： Joe T. May ,  Edward A. Casacia

IPC: G01J1/16 ,  G01N21/01 ,  G01N21/09 ,  G01N21/25 ,  G01N21/85 ,  G03F7/30

CPC classification number: G01N21/251 ,  G01N21/8507 ,  G03F7/30 ,  G01J1/1626 ,  G01J2001/161 ,  G01J2001/1636 ,  G01N2021/0162 ,  G01N21/09 ,  G01N2201/0693 ,  G01N2201/12761

Abstract: Instrumentation for measuring the amount of material dissolved in a liquid solution which utilizes electro-optic technology based on the Beer-Lambert Law is implemented either as a portable, battery powered model or integrated in an automated process monitoring system. In the portable, battery powered model, a sample probe (14) is inserted into a solution to be measured. The results of the measurement are displayed on a display (22). The displayed results are frozen for a predetermined period of time at the expiration of which, the power is turned off to conserve battery power. In the automated process monitoring model, a solution loading analyzer (100) is supplied with a sample of solution to be analyzed. A probe (14) positioned in a measurement well (200) is used to determine the ratio of incident light to light transmitted through the sample. A spray nozzle (212) is used for cleaning the probe head (16).

Abstract translation: 用于测量溶解在基于Beer-Lambert法的电光技术的液体溶液中的材料的量的仪器可以作为便携式，电池供电型或者集成在自动化过程监控系统中来实现。 在便携式电池供电的模型中，将样品探针（14）插入待测量的溶液中。 测量结果显示在显示器（22）上。 显示的结果被冻结预定的时间段，在此期间电源被关闭以节省电池电力。 在自动化过程监控模型中，向溶液负载分析仪（100）提供待分析的溶液样品。 位于测量井（200）中的探头（14）用于确定入射光与穿过样品的光的比例。 喷嘴（212）用于清洁探头（16）。

公开(公告)号：WO2008048371A2

公开(公告)日：2008-04-24

申请号：PCT/US2007008394

申请日：2007-04-04

Applicant: SINGULEX INC ,  GOIX PHILIPPE ,  PUSKAS ROBERT ,  TODD JOHN ,  LIVINGSTON RICHARD ,  HELD DOUGLAS

Inventor： GOIX PHILIPPE ,  PUSKAS ROBERT ,  TODD JOHN ,  LIVINGSTON RICHARD ,  HELD DOUGLAS

IPC: B01J19/00 ,  C40B30/04 ,  G01N21/63 ,  G01N33/566 ,  G01N33/68 ,  G01N35/10

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples to levels of 1 femtomolar, 1 attomolar, or lower. The methods, kits, and compositions also allow the determination of concentration over a wide range, e.g., 7-log range, without need for sample dilution.

Abstract translation: 公开了用于分子的高灵敏度检测的方法，试剂盒和组合物。 方法，试剂盒和组合物可用于测定样品中分子的浓度为1飞摩尔，1 attomolar或更低的水平。 方法，试剂盒和组合物还允许在宽范围内测定浓度，例如7-log范围，而不需要样品稀释。

公开(公告)号：WO2005015241A1

公开(公告)日：2005-02-17

申请号：PCT/GB2004/003093

申请日：2004-07-16

Applicant: COUNCIL FOR THE CENTRAL LABORATORY OF THE RESEARCH COUNCILS ,  JONES, Gareth ,  CLARKE, David

Inventor： JONES, Gareth ,  CLARKE, David

IPC: G01N33/92

CPC classification number: G01N21/19 ,  G01N21/274 ,  G01N2201/12761

Abstract: The determination of the HDL content of a lipoprotein mixture using circular dichroism spectrometry. A first method comprises measuring the circular dichroism (CD) of the sample at a wavelength or wavelengths around at least one of the three CD maxima characteristic of the α-helix secondary structure, and determining the HDL concentration from said measurement. A second method comprises obtaining a circular dichroism (CD) spectrum of the sample, analysing the CD spectrum to determine the α-helix content of the sample, and determining the HDL concentration from the α-helix content.

Abstract translation: 使用圆二色光谱法测定脂蛋白混合物的HDL含量。 第一种方法包括测量样品在α-螺旋二级结构的三个CD最大值特征中的至少一个波长或波长附近的圆二色性（CD），并从所述测量确定HDL浓度。 第二种方法包括获得样品的圆二色性（CD）光谱，分析CD光谱以确定样品的α-螺旋含量，以及从α-螺旋含量确定HDL浓度。

公开(公告)号：WO2004053467A3

公开(公告)日：2004-08-12

申请号：PCT/EP0310617

申请日：2003-09-24

Applicant: INST TEXTILCHEMIE DER DEUTSCHE ,  SCHNEIDER REINHOLD

Inventor： SCHNEIDER REINHOLD

IPC: G01N15/06 ,  G01N21/27 ,  G01N21/31 ,  G01N21/53 ,  G01N21/85 ,  G01N33/28

CPC classification number: G01N21/8507 ,  G01N15/06 ,  G01N21/274 ,  G01N21/31 ,  G01N21/534 ,  G01N2201/0228 ,  G01N2201/062 ,  G01N2201/12753 ,  G01N2201/12761 ,  G01N2201/128

Abstract: The invention relates to an optical sensor (1) for determining particle and/or dye concentrations in liquid or gaseous media and to a method for operating the same. The optical sensor (1) comprises at least one measuring head. The measuring head consists of an emitter unit (2) with a semiconductor emitting element (9), which emits visible emission light beams (8), and with a receiver unit (3) with a semiconductor receiving element (10). The portion of the emission light beams (8), which pass through an absorption section containing liquid or gaseous medium, is guided onto the receiving element (10). An evaluating unit (6) is coupled to the measuring head via electric leads (4, 4'), and the received signals, which are present at the output of the semiconductor receiving element (10), are evaluated inside said evaluating unit in order to determine the particle or die concentration.

Abstract translation: 本发明涉及用于确定液体或气体介质中的颗粒和/或染料浓度的光学传感器（1）及其操作方法。 光学传感器（1）具有至少一个测量头。 测量头包括一个发射器单元（2）与Einein可见光透射光束（8）的发光半导体发射器元件（9）和接收器单元（3）的半导体接收元件（10）。 在具有通过部分透射光束（8）的液体或气体介质的吸收路径的接收元件（10）上被引导。 在测量头经由电引线（4，4`）耦合到评估单元（6）连接，其中在半导体接收元件的输出（10）挂起的接收信号，以确定颗粒或染料浓度进行评估。

公开(公告)号：WO1990011509A1

公开(公告)日：1990-10-04

申请号：PCT/US1989001764

申请日：1989-05-02

Applicant: ELECTRONIC INSTRUMENTATION AND TECHNOLOGY, INC.

Inventor： ELECTRONIC INSTRUMENTATION AND TECHNOLOGY, INC. ,  MAY, Joe, T. ,  CASACIA, Edward, A.

IPC: G01N21/59

CPC classification number: G01N21/251 ,  G01J1/1626 ,  G01J2001/161 ,  G01J2001/1636 ,  G01N21/09 ,  G01N21/8507 ,  G01N2021/0162 ,  G01N2201/0693 ,  G01N2201/12761 ,  G03F7/30

Abstract: Instrumentation for measuring the amount of material dissolved in a liquid solution which utilizes electro-optic technology based on the Beer-Lambert Law is implemented either as a portable, battery powered model or integrated in an automated process monitoring system. In the portable, battery powered model, a sample probe (14) is inserted into a solution to be measured. The results of the measurement are displayed on a display (22). The displayed results are frozen for a predetermined period of time at the expiration of which, the power is turned off to conserve battery power. In the automated process monitoring model, a solution loading analyzer (100) is supplied with a sample of solution to be analyzed. A probe (14) positioned in a measurement well (200) is used to determine the ratio of incident light to light transmitted through the sample. A spray nozzle (212) is used for cleaning the probe head (16).

Abstract translation: 用于测量溶解在基于Beer-Lambert法的电光技术的液体溶液中的材料的量的仪器可以作为便携式，电池供电型或者集成在自动化过程监控系统中来实现。 在便携式电池供电的模型中，将样品探针（14）插入待测量的溶液中。 测量结果显示在显示器（22）上。 显示的结果被冻结预定的时间段，在此期间电源被关闭以节省电池电力。 在自动化过程监控模型中，向溶液负载分析仪（100）提供待分析的溶液样品。 位于测量井（200）中的探头（14）用于确定入射光与穿过样品的光的比例。 喷嘴（212）用于清洁探头（16）。

公开(公告)号：US20240168000A1

公开(公告)日：2024-05-23

申请号：US18516847

申请日：2023-11-21

Applicant: MOTION METRICS INTERNATIONAL CORP.

Inventor： Obada Alhumsi ,  Sophia Alexandra Helen Piche ,  Peter Shang Yu Hsieh ,  Mohammad Sameti ,  Saeed Karimifard ,  Thomas C. Chudy

IPC: G01N33/24 ,  G01N1/28 ,  G01N21/31

CPC classification number: G01N33/24 ,  G01N1/286 ,  G01N21/31 ,  G01N2201/12761 ,  G01N2201/1296

Abstract: Spectral imaging systems are used to gather spectral image data on earthen material moving within an earthen material processing system, such as a mineral processing system or cement plant. Machine learning models such as 3D convolutional neural networks may be utilized to process the spectral image data to determine or classify one or more characteristics of the earthen material, such as ore grade, mineral alteration(s), moisture content, lithology and/or mineralogy. Such earthen material characteristics, or classifications thereof, may then be utilized to automatically control one or more operational characteristics of the earthen material processing system, such as rotational speed of milling equipment or flow rates of water or chemicals added to milling equipment or mineral concentration systems.