公开(公告)号：US20070263214A1

公开(公告)日：2007-11-15

申请号：US11346982

申请日：2006-02-03

Applicant: William Fateley ,  Ronald Coifman ,  Frank Geshwind ,  Richard DeVerse

Inventor： William Fateley ,  Ronald Coifman ,  Frank Geshwind ,  Richard DeVerse

IPC: G01J3/12 ,  G02B5/20 ,  G02F1/29

CPC classification number: G02B27/1013 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/027 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J3/2823 ,  G01J3/2846 ,  G01J3/2889 ,  G01J3/32 ,  G01J3/42 ,  G01J3/433 ,  G01J3/457 ,  G01J2003/2866 ,  G01N21/39 ,  G01N2021/393 ,  G01N2021/6463 ,  G02B26/0833 ,  G02B26/0841 ,  G02B27/1086 ,  G02B27/126

Abstract: Encoded spatio-spectral information processing is performed using a system having a radiation source, wavelength dispersion device and two-dimensional switching array, such as digital micro-mirror array (DMA). In one aspect, spectral components from a sample are dispersed in space and modulated separately by the switching array, each element of which may operate according to a predetermined encoding pattern. The encoded spectral components can then be detected and analyzed. In a different aspect, the switching array can be used to provide a controllable radiation source for illuminating a sample with radiation patterns that have predetermined characteristics and separately encoded components. Various applications are disclosed.

Abstract translation: 使用具有辐射源，波长色散器件和二维开关阵列（例如数字微镜阵列（DMA））的系统执行编码空间光谱信息处理。 在一个方面，来自样本的频谱分量被分散在空间中，并且由开关阵列分开调制，开关阵列的每个元件可以根据预定的编码模式进行操作。 然后可以检测和分析编码的光谱分量。 在不同的方面，开关阵列可以用于提供用于利用具有预定特征的辐射图案和分开编码的部件来照射样本的可控辐射源。 公开了各种应用。

公开(公告)号：US20070114417A1

公开(公告)日：2007-05-24

申请号：US11539962

申请日：2006-10-10

Applicant: JAMES HOBBY ,  MARTIN LOPEZ

Inventor： JAMES HOBBY ,  MARTIN LOPEZ

IPC: G01J5/02

CPC classification number: G01N21/3504 ,  G01J3/457 ,  G01N21/274 ,  G01N21/37 ,  G01N21/61

Abstract: Correlation spectroscopy measure is improved by correcting for cross interference. This is achieved through applying different gains to the output signals whereby the effect of background interferent species can be calculated and an automatic correction factor applied.

Abstract translation: 通过校正交叉干扰来改进相关光谱测量。 这通过对输出信号应用不同的增益来实现，从而可以计算背景干扰物质的效果并应用自动校正因子。

公开(公告)号：US20060279731A1

公开(公告)日：2006-12-14

申请号：US11451690

申请日：2006-06-13

Applicant: Eckhard Beyer ,  Jorg Hoschele ,  Steffen Nowotny ,  Alexander Ohnesorge ,  Jurgen Steinwandel

Inventor： Eckhard Beyer ,  Jorg Hoschele ,  Steffen Nowotny ,  Alexander Ohnesorge ,  Jurgen Steinwandel

IPC: G01J3/30 ,  G01J3/28

CPC classification number: G01J3/443 ,  G01J3/1809 ,  G01J3/457 ,  G01N21/718

Abstract: In material depositing processes such as welding or thermal spraying the large variety of processes and material parameters necessitate a broad range of the resulting characteristics of the applied material. The task of the present invention is comprised of providing a process and a device for determining the quality of specific layer characteristics, in particular their adhesion or strength of joining to the base material. This task is solved thereby, that as the quality characteristic there is employed the degree of mixing of the applied material with the base material.

Abstract translation: 在诸如焊接或热喷涂的材料沉积过程中，各种各样的工艺和材料参数需要施加材料的所得特征的广泛范围。 本发明的任务包括提供用于确定特定层特性的质量的方法和装置，特别是其与基材的接合或强度。 因此解决了这个任务，因为质量特性使用了应用材料与基材的混合程度。

公开(公告)号：US07030990B2

公开(公告)日：2006-04-18

申请号：US10182844

申请日：2001-02-20

Applicant: Constantine Dean Capetanopoulos

Inventor： Constantine Dean Capetanopoulos

IPC: G01B9/02

CPC classification number: G01N21/3504 ,  G01J3/447 ,  G01J3/457 ,  G01J2003/2866

Abstract: A spectrometer for determining the concentration of a substance within a sample comprises a. a radiation source (11) for supplying radiation to the sample to be measured; b. a filter (15) for filtering radiation transmitted by the sample, the filter having a number of pass bands at wavelengths corresponding to absorption peaks in the absorption spectrum of the sample to be detected, the filter being responsive to an applied signal to modulate the wavelengths of the pass bands; and, c. a detector (16) for detecting the filtered radiation, the detector being responsive to the applied signal to determine the relative intensities of the maxima and minima in the absorption spectra of the substance, characterized in that the radiation source is selectively activated in response to the applied signal.

Abstract translation: 用于确定样品中物质浓度的光谱仪包括a。 辐射源（11），用于向被测样品供给辐射; b。 滤波器（15），用于滤波由样品透射的辐射，滤光器具有多个通过带，其波长对应于待检测样品的吸收光谱中的吸收峰，该滤波器响应所施加的信号以调制波长 的通带; 和，c。 检测器（16），用于检测经滤波的辐射，所述检测器响应所施加的信号以确定所述物质的吸收光谱中的最大值和最小值的相对强度，其特征在于，所述辐射源根据 应用信号。

公开(公告)号：US06965113B2

公开(公告)日：2005-11-15

申请号：US09779461

申请日：2001-02-09

Applicant: Peet Kask ,  Stefan Jäger ,  Kaupo Palo ,  Ülo Mets ,  Karsten Gall

Inventor： Peet Kask ,  Stefan Jäger ,  Kaupo Palo ,  Ülo Mets ,  Karsten Gall

IPC: G01J3/28 ,  G01J3/44 ,  G01J3/457 ,  G01N21/64

CPC classification number: G01N21/64 ,  G01J3/4406 ,  G01J3/457 ,  G01J2003/2866 ,  G01N21/6408 ,  G01N21/6458 ,  G01N2021/6421 ,  G01N2021/6463

Abstract: A method for distinguishing samples having flourescent particles includes (a) monitoring intensity fluctuations of fluorescence emitted by the particles in at least one measurement volume by detecting sequences of photon counts by at least one photon detector, (b) determining, from the sequences of photon counts, intermediate statistical data involving at least two probability functions of the number of photon counts detected in different sets of counting time intervals, and (c) determining from the intermediate statistical data a distribution of particles as a function of at least two arguments, wherein one argument is a specific brightness of the particles, or a measure thereof, and another argument is a diffusion coefficient of the particles, or a measure thereof.

Abstract translation: 用于区分具有荧光颗粒的样品的方法包括（a）通过至少一个光子检测器检测光子计数序列来监测由至少一个测量体积中的颗粒发射的荧光的强度波动，（b）从光子序列 计数涉及在不同的计数时间间隔集中检测的光子计数的至少两个概率函数的中间统计数据，以及（c）从中间统计数据确定作为至少两个参数的函数的粒子分布，其中 一个参数是颗粒的特定亮度或其度量，另一个参数是颗粒的扩散系数或其度量。

公开(公告)号：US06853449B2

公开(公告)日：2005-02-08

申请号：US10352828

申请日：2003-01-28

Applicant: G. Benjamin Hocker

Inventor： G. Benjamin Hocker

IPC: G01J3/28 ,  G01J3/457 ,  G01N21/17 ,  G01N29/24 ,  G01J3/18

CPC classification number: G01N29/2425 ,  G01J3/28 ,  G01J3/457 ,  G01N21/1702 ,  G01N2021/1725 ,  G01N2201/0635 ,  G01N2201/0691

Abstract: A programmable substance detector includes a light source, a sample cell, a programmable diffraction grating positioned to receive light from the light source and to direct diffracted light to the sample cell, and a detector associated with the cell to detect a match between a characteristic of the diffracted light and a corresponding characteristic of a substance within the cell.

Abstract translation: 可编程物质检测器包括光源，样品池，定位成接收来自光源的光并将衍射光引导到样品池的可编程衍射光栅，以及与该电池相关联的检测器，用于检测 衍射光和细胞内物质的相应特征。

公开(公告)号：US20030090670A1

公开(公告)日：2003-05-15

申请号：US10182844

申请日：2002-10-09

Inventor： Constantine Dean Capetanopoulos

IPC: G01B009/02

CPC classification number: G01N21/3504 ,  G01J3/447 ,  G01J3/457 ,  G01J2003/2866

Abstract: A spectrometer for determining the concentration of a substance within a sample comprises a. a radiation source (11) for supplying radiation to the sample to be measured; b. a filter (15) for filtering radiation transmitted by the sample, the filter having a number of pass bands at wavelengths corresponding to absorption peaks in the absorption spectrum of the sample to be detected, the filter being responsive to an applied signal to modulate the wavelengths of the pass bands; and, c. a detector (16) for detecting the filtered radiation, the detector being responsive to the applied signal to determine the relative intensities of the maxima and minima in the absorption spectra of the substance, characterized in that the radiation source is selectively activated in response to the applied signal.

Abstract translation: 用于确定样品中物质浓度的光谱仪包括a。 辐射源（11），用于向被测样品供给辐射; b。 滤波器（15），用于滤波由样品透射的辐射，滤光器具有与待检测样品的吸收光谱中的吸收峰对应的波长的多个通带，滤光器响应所施加的信号以调制波长 的通带; 和，c。 检测器（16），用于检测经滤波的辐射，所述检测器响应所施加的信号以确定所述物质的吸收光谱中的最大值和最小值的相对强度，其特征在于，所述辐射源根据 应用信号。

公开(公告)号：US06556296B1

公开(公告)日：2003-04-29

申请号：US09509491

申请日：2000-06-12

Applicant: Kaupo Palo

Inventor： Kaupo Palo

IPC: G01N2164

CPC classification number: G01J3/4406 ,  G01J3/457 ,  G01J2003/2866 ,  G01N15/14 ,  G01N21/6408

Abstract: A method for characterizing samples having fluorescent particles, by monitoring fluctuating intensities of radiation emitted by said particles in at least one measurement volume, the monitoring being performed by at least one detection means, said method comprising the steps of: a) measuring in a repetitive mode a length of time intervals between photon counts, b) determining a function or a series of functions of the length of said time intervals, c) determining a function of at least one specific physical property of said particles on basis of said function or said series of functions of the length of time intervals, by finding a close fit between the experimentally determined and a theoretical function or series of functions of the length of said time intervals, the latter of which takes into account parameters of the spatial brightness function characteristic for the optical set-up.

Abstract translation: 一种用于表征具有荧光颗粒的样品的方法，通过在至少一个测量体积中监测由所述颗粒发射的辐射的波动强度，所述监测由至少一个检测装置执行，所述方法包括以下步骤：a）重复测量 模拟光子计数之间的时间间隔的长度，b）确定所述时间间隔的长度的函数或一系列函数，c）基于所述函数或所述函数确定所述粒子的至少一个特定物理特性的函数， 通过发现实验确定的理论功能或所述时间间隔的长度的一系列功能之间的紧密配合，其中后者考虑了空间亮度函数特性的参数， 光学设置。

公开(公告)号：US20020150299A1

公开(公告)日：2002-10-17

申请号：US09932438

申请日：2001-08-16

Inventor： David A.B. Miller

IPC: G06K009/76

CPC classification number: G01J3/453 ,  G01J3/26 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/457

Abstract: A method for adaptive spectral sensing developed for a two-dimensional image made up of picture elements. The method calls for illuminating at least one of the picture elements with an input light and deriving a time-varying spectral signal from the input light for that picture element. The time-varying spectral signal is processed with a time-varying reference signal by using a mathematical function such as convolution, multiplication, averaging, integrating, forming an inner product, matched filtering, addition, subtraction or division to obtain a processed output value for the picture element and this output value is then used in determining a spectral characteristic of the input light. The time-varying spectral signal is conveniently derived by optical filtering of the input light yielding an optical time-varying spectral signal. This method can be used by itself or in combination with at least one other adaptive technique such as adaptive spatial sensing and/or adaptive temporal sensing.

Abstract translation: 一种用于由图像元素组成的二维图像的自适应光谱感测方法。 该方法要求用输入光照射至少一个像素，并从该图像元素的输入光导出时变光谱信号。 时变频谱信号通过使用诸如卷积，乘法，平均，积分，形成内积，匹配滤波，加法，减法或除法等数学函数，用时变参考信号进行处理，以获得处理后的输出值 然后将像素和该输出值用于确定输入光的光谱特性。 时变光谱信号通过对产生光时变光谱信号的输入光的光学滤波方便地得出。 该方法可以单独使用或与至少一种其他自适应技术组合使用，例如自适应空间感测和/或自适应时间感测。

公开(公告)号：US06376843B1

公开(公告)日：2002-04-23

申请号：US09338439

申请日：1999-06-23

Applicant: Kaupo Palo

Inventor： Kaupo Palo

IPC: G01N2164

CPC classification number: G01J3/4406 ,  G01J3/457 ,  G01J2003/2866 ,  G01N21/6408 ,  G01N21/6458 ,  G01N2021/6421 ,  G01N2021/6463

Abstract: A method characterizes fluorescent molecules or other particles in samples by a) monitoring fluctuating intensity of fluorescence emitted by the molecules or other particles in at least one measurement volume of a non-uniform spatial brightness profile by measuring numbers of photon counts in primary time intervals by a single or more photon detectors, b) determining at least one distribution function of numbers of photon counts, {circumflex over (P)}(n), from the measured numbers of photon counts, c) determining physical quantities characteristic to the particles by fitting the experimentally determined distribution function of numbers of photon counts, wherein the fitting procedure involves calculation of a theoretical distribution function of the number of photon counts P(n) through its generating function, defined as G ⁡ ( ζ _ ) = ∑ n ⁢   ⁢ ζ _ n ⁢ P ⁡ ( n ) .

Abstract translation: 一种通过以下方式来表征样品中的荧光分子或其它颗粒：a）通过在一次时间间隔中测量光子计数的数量来监测在一次时间间隔中的光子计数的数量，通 单个或多个光子检测器，b）根据测量的光子计数确定至少一个光子计数数目的分布函数（从（P）}（n）回旋），c）通过以下方式确定颗粒特性的物理量： 拟合实验确定的光子计数数量的分布函数，其中拟合过程涉及通过其生成函数计算光子计数P（n）的数量的理论分布函数，定义为