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    STEM CELLS
    31.
    发明申请
    STEM CELLS 审中-公开
    干细胞

    公开(公告)号：WO2005059113A1

    公开(公告)日：2005-06-30

    申请号：PCT/GB2004/005365

    申请日：2004-12-20

    Applicant: OMNICYTE LTD ,  GORDON, Myrtle ,  HABIB, Nagy

    Inventor： GORDON, Myrtle ,  HABIB, Nagy

    IPC: C12N5/00

    CPC classification number: C12N5/0607 ,  A61K2035/124 ,  C12N2501/125 ,  C12N2501/22 ,  C12N2501/23 ,  C12N2533/78

    Abstract: The present invention relates to an isolated stem cell population wherein said stem cells are CD34 + , capable of self regeneration, capable of differentiation into ectodermal, mesodermal and endodermal cells and capable of adhering to tissue-culture grade plastic as well as to methods of isolation of said cells, methods of culturing and differentiation thereof, the progeny of such methods of differentiation as well as uses, including therapeutic uses of the stem cells and their differentiated progeny.

    Abstract translation: 本发明涉及分离的干细胞群体，其中所述干细胞是能够自我再生的能够分化成外胚层，中胚层和内胚层细胞并且能够粘附于组织培养级塑料的干细胞以及方法 所述细胞的分离方法，培养和分化方法，这些分化方法的后代以及包括干细胞及其分化后代的治疗用途的用途。

    TREATMENT USING IMPLANTABLE DEVICES
    32.
    发明申请
    TREATMENT USING IMPLANTABLE DEVICES 审中-公开
    使用可植入装置的治疗

    公开(公告)号：WO0004946A2

    公开(公告)日：2000-02-03

    申请号：PCT/GB9902393

    申请日：1999-07-22

    Applicant: IMP COLLEGE INNOVATIONS LTD ,  HABIB NAGY ADLY ,  SANGSTER ALAN JOHN

    Inventor： HABIB NAGY ADLY ,  SANGSTER ALAN JOHN

    IPC: A61B5/01 ,  A61B5/00 ,  A61F2/02 ,  A61N1/372 ,  A61N1/378 ,  A61N1/40 ,  A61N2/10 ,  A61N5/02 ,  A61N5/04 ,  A61N

    CPC classification number: A61N5/02 ,  A61B5/0031 ,  A61F2250/0002 ,  A61N1/37223 ,  A61N1/3787 ,  A61N1/40

    Abstract: A method of treatment using implantable devices is disclosed. The method comprises (a) implanting into the body of the human or non-human animal (i) a rectenna capable of receiving electromagnetic radiation in the microwave frequency range and of generating and/or storing electrical energy therefrom; and (ii) an electrically operated therapeutic device arranged to receive electrical energy from said rectenna; and (b) directing electromagnetic radiation in the microwave frequency range from a source external to the body being treated towards the position of the implanted rectenna so as to generate electrical energy to actuate said therapeutic device.

    Abstract translation: 公开了一种使用可植入装置的治疗方法。 该方法包括：（a）植入人或非人动物体内（i）能够接收微波频率范围内的电磁辐射并从其产生和/或储存电能的整流天线; 和（ii）被布置成从所述直肠天线接收电能的电操作治疗装置; 和（b）将微波频率范围内的电磁辐射引导到被处理的身体外部的源朝向植入的整流天线的位置，以产生电能来致动所述治疗装置。

    Methods of treatment
    37.
    发明专利
    Methods of treatment 未知

    公开(公告)号：GB9824436D0

    公开(公告)日：1999-01-06

    申请号：GB9824436

    申请日：1998-11-06

    Applicant: HABIB NAGY A

    IPC: A61M1/10 ,  A61M16/00

    Abstract: The use of an implantable pump in the treatment of a condition characterised by inadequate fluid flow, in vivo, in or through a vessel, channel or conduit, is disclosed. This comprises inserting said implantable pump into said vessel, channel or conduit and causing it to operate when required. Control is preferably by telemetric means. Conditions susceptible to treatment in this way include urinary incontinence, pulmonary hypertension and inadequate pulmonary ventilation.

    38.
    发明专利
    未知

    公开(公告)号：DK537087A

    公开(公告)日：1987-12-07

    申请号：DK537087

    申请日：1987-10-14

    Applicant: HABIB NAGY ADLY

    Inventor： HABIB NAGY ADLY ,  WOOD CHRISTOPHER BARRY ,  APOSTOLOV KOSTA ,  BARKER WILLIAM ROLAND

    IPC: C07C57/02 ,  A61K31/20 ,  A61K31/23 ,  A61P31/12 ,  A61P35/00 ,  C07C51/00 ,  C07C53/126 ,  C07C53/19 ,  C07C57/12 ,  C07C67/00

    Abstract: The invention is concerned with the use of certain fatty acids and inhibitors of an enzyme in effecting modifications to the lipid structure of cell membranes. The invention also relates to the formulation of pharmaceutical compositions and medicaments and to such products per se; to the treatment of a variety of clinical and veterinary disorders associated with a lowering of the saturation index of cell membranes, including malignancies, viral disorders and AIDS; and to the use of the active materials of the invention in the relief of pain. The active principals in the present invention are saturated fatty acids having from 12 to 28 carbon atoms in the alkyl chain, e.g. stearic acid, or pharmaceutically acceptable derivatives thereof; and inhibitors of the enzyme DELTA -9 desaturase, e.g. sterculic acid and malvalic acid or pharmacologically active derivatives or analogues thereof.

    Conditioned medium from Omnicytes for anticancer therapy
    40.
    发明专利
    Conditioned medium from Omnicytes for anticancer therapy 未知

    公开(公告)号：GB2464200A

    公开(公告)日：2010-04-14

    申请号：GB0917359

    申请日：2009-10-02

    Applicant: HABIB NAGY A ,  GORDON MYRTLE

    Inventor： HABIB NAGY A ,  GORDON MYRTLE

    IPC: A61K35/12 ,  A61K38/02 ,  A61K38/17 ,  A61K38/19 ,  A61K38/20 ,  A61K38/36 ,  A61P35/00

    Abstract: The conditioned medium from ECACC 04092401 Omnicytes, which are CD34+, wherein that medium comprises apoptosis modulating agents. Preferably the medium is for therapeutic use in the treatment of a hyperproliferative disorder such as skin disorders or cancer and particularly non-small cell lung carcinoma. The conditioned medium may have activity to promote the apoptosis of rapidly dividing cells or to promote the survival of slowly dividing cells and its activity is blocked by TNF-alpha blocking antibodies. Also disclosed is conditioned medium from other stem cells, particularly CD34+ stem cells having pluripotency and the ability to adhere plastic, for therapeutic use in the treatment of cancers and hyperproliferative disorders and in vitro use for apoptosis activation or inhibition.

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