Abstract:
가. 청구범위에 기재된 발명이 속한 기술분야 통신단말기의 멜로디 입력방법에 관한 것이다. 나. 발명이 해결하려고 하는 기술적 과제 통신단말기에 사용자가 원하는 멜로디를 입력할 수 있는 통신단말기의 멜로디 입력방법을 제공함에 있다. 다. 발명의 해결방법의 요지 각 음과 음표 데이터를 저장하고 있는 제 1메모리와 멜로디 코드를 저장하는 제 2메모리를 구비하는 통신단말기의 멜로디 입력방법에 있어서, 소정의 키입력에 의해 멜로디 입력 모드로 설정되면 음 및 음표 키데이터의 입력을 감지하는 제 1과정과, 감지된 음 및 음표 키데이터에 대한 해당 정보를 상기 제 1메모리로부터 독출하여 멜로디 코드를 생성하는 제 2과정과, 소정의 키입력에 의해 상기 생성한 멜로디 코드를 제 2메모리에 저장하는 제3과정으로 이루어짐을 특징으로 한다. 라. 발명의 중요한 용도 통신단말기에 이용한다.
Abstract:
제조설비의 기구적인 동작을 위해 사용되는 구동모터등의 동력원에 파워를 공급하기 위해 연결되는 파워라인에 관한 것이다. 본 발명은 구동모터(13) 등의 동력원에 파워를 공급하기 위한 것으로, 동력원과 전기적으로 접속하기 위한 커넥터(12)와 연결되는 반도체 제조설비의 파워라인에 있어서, 반복적으로 유동하거나 휘어짐 등의 변형을 유발하는 부분의 구조를 코일형상으로 형성하여 탄성과 신축성을 부여한 것이다. 따라서 커넥터와 연결되는 부위에 탄성 및 신축성이 부여됨으로써 휘어짐 등의 변형에 의한 단선이 방지되는 것이고, 이로써 설비의 가동율을 증대시켜 생산성이 향상되는 효과가 있다.
Abstract:
혈청과 같은 생화학 시료에 포함된 특정 성분의 농도를 측정하는 방법과, 이 방법을 이용하여 검사 결과의 신뢰도를 추정하는 방법이 개시된다. 개시된 특정 성분의 농도를 측정하는 방법은, 적어도 한 종류의 특정 성분이 포함되고, 그 포함된 특정 성분의 농도가 서로 다른 자연수 n 개의 표준 시료(standard sample)를 준비하는 표준 시료 준비 단계와, 서로 다른 파장 대역을 갖는 자연수 m개의 광을 준비된 n 개의 표준 시료에 차례로 조사(照査)하고 이를 투과한 투과광을 감지함으로써, 표준 시료에 포함된 특정 성분의 농도 및 광의 파장 대역에 따른 자연수 m×n 개의 흡광도를 측정하는 흡광도 측정 단계와, 측정된 m×n 개의 흡광도를 이용하여, m 개의 파장 대역 광의 흡광도를 독립 변수로 포함하는 특정 성분의 농도에 관한 회귀식(regression equation)을 구하는 회귀식 결정 단계와, 생화학 시료 또는 증류수에 의해 희석된 생화학 시료를 대상으로 m 개의 파장 대역의 흡광도를 측정하고, m 개의 흡광도를 회귀식의 대응되는 독립 변수에 대입하여 특정 성분의 농도를 산출하는 회귀식 적용 단계;를 구비한다.
Abstract:
본 발명은 12 종의 호흡기 질환을 야기시키는 박테리아의 표적 서열을 증폭시킬 수 있는 프라이머 세트, 12 종의 박테리아의 표적 서열에 특이적으로 혼성화하는 프로브 세트, 상기 프로브 세트가 고정화되어 있는 마이크로어레이 및 상기 프로브 세트를 이용하여 12 종의 박테리아의 존재를 검출하는 방법을 제공한다. 프라이머, 프로브, 독성인자
Abstract:
A centrifugal force-based microfluidic device having sample distribution structure is provided to distribute sample into a plurality of reaction chambers by one fluid sample transfer operation, and reduce sample distribution time by performing the sample distributing function in the microfluidic device without adding additional resistance to a moving path of a fluid sample, and a microfluidic system including the microfluidic device is provided. A centrifugal force-based microfluidic device comprises: a rotatable platform(21); a sample chamber(30) which is disposed in the platform, and which contains a fluid sample; a distribution channel(40) which is connected to an outlet(33) of the sample chamber, has a first section extending an outer side of rotation radius of the platform and a second section extending along the circumferential direction from the first section, and is constant in fluid resistance along the entire section; a plurality of sealed reaction chambers(50) disposed at an outer side of the radius direction of the distribution channel in the platform; and a plurality of inlet channels(42) for connecting the second section of the distribution channel to the reaction chambers respectively, wherein the centrifugal force-based microfluidic device has sample distribution structure for distributing the fluid sample contained in the sample chamber into the sealed reaction chambers through the distribution channel using centrifugal force according to rotation of the platform. Further, partition walls for separating the inlet channel into sub channel are additionally comprised in the inlet channels.
Abstract:
A method and a device for amplifying and hybridizing nucleic acids in a single solid support are provided to reduce time and labor required for treatment and analysis by processing all steps in the same chip continuously, increase the sensitivity due to no sample loss by removing a sample transferring step, and lower danger of cross-contamination significantly. A method for amplifying and hybridizing nucleic acids in a single solid support comprises the steps of: (a) introducing a sample including nucleic acids and a reagent for amplifying nucleic acids into a chamber having a solid support surface where a probe is fixed; (b) performing a nucleic acid amplification reaction to amplify the nucleic acids; and (c) hybridizing the amplified nucleic acids with the fixed probe, wherein the solid support is selected from the group consisting of a silicone wafer, a slide glass, polystyrene and a metallic plate, the nucleic acid amplification reaction is performed by a polymerase chain reaction(PCR), a ligase chain reaction, a nucleic acid sequence-based amplification, a transcription-based amplification system, a strand displacement amplification or an amplification through a Qbeta replicase, the nucleic acid amplifying reagent includes a PCR primer, a DNA polymerase, dNTPs, and a buffer. A device for amplifying and hybridizing nucleic acids in the single solid support comprises: a chamber having the solid support surface where the probe is fixed; and a heating portion and a cooling portion which are attached to the chamber and heat and cool down the chamber. The device further comprises: a nucleic acid containing sample storage portion which is communicated with the chamber through a microchannel and supplies a nucleic acid containing sample to the chamber; and a nucleic acid amplifying reagent storage portion which is communicated with the chamber through the microchannel and supplies a nucleic acid amplifying reagent to the chamber.
Abstract:
A primer set and probe set for predicting alcohol-degrading ability and hangover development is provided to improve rapidness and convenience of prediction by amplifying at least one target sequence selected from ALDH2(acetaldehyde dehydrogenase 2) gene, CYP2E1(cytochrome P450 2E1) gene and ADH2(alcohol dehydrogenase 2) gene. An oligonucleotide probe set capable of hybridizable with at least one target sequence selected from exon XII region of ALDH2 gene, 5'-regulating region of CYP2E1 gene and the exon III region and exon IX region of ADH2 gene is selected from (1) an oligonucleotide probe capable of hybridizable with the exon XII region of ALDH2 gene containing 10 or more consecutive nucleotide fragments containing a 11st base in the nucleotide sequence of SEQ ID NO:15, (2) an oligonucleotide probe capable of hybridizable with the 5-regulating region of CYP2E1 gene containing 10 or more consecutive nucleotide fragments containing a 12nd base in the nucleotide sequence of SEQ ID NO:17, (3) an oligonucleotide probe capable of hybridizable with the exon III region of ADH gene containing 10 or more consecutive nucleotide fragments containing a 12nd base in the nucleotide sequence of SEQ ID NO:19, (4) an oligonucleotide probe capable of hybridizable with the exon IX region of ADH2 gene containing 10 or more consecutive nucleotide fragments containing a 12nd base in the nucleotide sequence of SEQ ID NO:21, and (5) an oligonucleotide probe capable of hybridizable with the exon XII region of ADH2 gene containing 10 or more consecutive nucleotide fragments containing a 13rd base in the nucleotide sequence of SEQ ID NO:23.
Abstract translation:提供了一种用于预测酒精降解能力和宿醉发育的引物组和探针组,以通过扩增至少一种选自ALDH2(乙醛脱氢酶2)基因,CYP2E1(细胞色素P450 2E1)基因和ADH2的靶序列来提高预测的快速性和便利性 (醇脱氢酶2)基因。 选自能够与选自ALDH2基因的外显子XII区域,CYP2E1基因的5'-调节区域和外显子III区域和ADH2基因的外显子IX区域的至少一种靶序列杂交的寡核苷酸探针组,其选自(1)寡核苷酸 能够与包含在SEQ ID NO:15的核苷酸序列中含有11个碱基的10个以上连续核苷酸片段的ALDH2基因的外显子XII区域杂交的探针,(2)能够与SEQ ID NO:15的核苷酸序列杂交的寡核苷酸探针 CYP2E1基因,其含有在SEQ ID NO:17的核苷酸序列中含有12个碱基的10个以上的连续核苷酸片段,(3)能够与含有10个以上连续核苷酸片段的ADH基因的外显子III区域杂交的寡核苷酸探针, SEQ ID NO:19的核苷酸序列的第12个碱基,(4)能够与含有10个以上共有的ADH2基因的外显子IX区域杂交的寡核苷酸探针 在SEQ ID NO:21的核苷酸序列中含有第12个碱基的连续核苷酸片段,和(5)能够与ADH2基因的外显子XII区域杂交的寡核苷酸探针,其含有在核苷酸中含有第13个碱基的10个以上的连续核苷酸片段 SEQ ID NO:23的序列。
Abstract:
A centrifugal force-based microfluidic device for detecting nucleic acids is provided to perform automatically a series of operations including isolation, purification and concentration of a target cell from a biological sample, extraction of nucleic acids from the concentrated target cell and detection of genetic properties by PCR(polymerase chain reaction) in one device rapidly. A centrifugal force-based microfluidic device(101) for detecting nucleic acids comprises: a rotatable platform(100); a target cell nucleic acid extraction portion which, in a microfluidic structure located within the platform, mixes microparticles capturing a target cell in the surface with a biological sample, isolates and purifies the microparticles capturing the target cells, and destroys the target cells by using the electromagnetic wave irradiated to the microparticles from the outside; and a PCR(polymerase chain reaction) unit(90) which, in the microfluidic structure located within the platform and connected to the target cell nucleic acid extraction portion, mixes the nucleic acid solution with PCR solution, and performs PCR by the thermal cycling through heat exchange between the mixture and a temperature control unit located in the outside of the platform, wherein the PCR unit contains a reaction chamber(80) for storing the PCR solution and mixes with the target cell nucleic acid solution from the target cell nucleic acid extraction portion, and a PCR chamber(92) for receiving the mixture of the reaction solution and nucleic acid solution by connecting to the reaction solution chamber. Further, the PCR chamber is sealed up while polymerase chain-reacts.