전단응력 측정을 이용한 생분자들간의 결합 여부 검출 방법
    31.
    发明授权
    전단응력 측정을 이용한 생분자들간의 결합 여부 검출 방법 有权
    电视节目播放时间表

    公开(公告)号:KR100442822B1

    公开(公告)日:2004-08-02

    申请号:KR1020010065484

    申请日:2001-10-23

    CPC classification number: C12Q1/6825 Y10S436/806 C12Q2565/107 C12Q2565/607

    Abstract: A method and sensor for detecting the binding of probes and target biomolecules by measuring a difference in the shear stress of the biomolecules bound to the surface of the sensor before and after hybridization of the target molecules to the probes, such as nucleic acids or proteins are provided. The shear stress can be measured sensitively and conveniently as an electrical signal without additional fluorescent labeling and without use of expensive additional devices.

    Abstract translation: 通过在靶分子与探针杂交之前和之后测量与传感器表面结合的生物分子的剪切应力的差异来检测探针和靶生物分子的结合的方法和传感器,所述探针如核酸或蛋白质是 提供。 剪切应力可以灵敏方便地作为电信号进行测量,无需额外的荧光标记,也无需使用昂贵的附加设备。 <图像>

    전기적 신호를 측정하는 PCR 증폭 산물을 검출하는 방법
    32.
    发明公开
    전기적 신호를 측정하는 PCR 증폭 산물을 검출하는 방법 失效
    通过测量电子信号检测PCR产物的方法

    公开(公告)号:KR1020040042021A

    公开(公告)日:2004-05-20

    申请号:KR1020020070141

    申请日:2002-11-12

    Abstract: PURPOSE: A method for detecting a PCR product by measuring the electrical signal is provided, thereby detecting the PCR product at real time, and reducing the size of the detecting system. CONSTITUTION: A method for detecting a PCR product by measuring the electrical signal comprises the steps of: (a) providing a pair of electrodes within a PCR reaction vessel; (b) conducting the PCR reaction; (c) inducing an electric field between the electrodes; and (d) measuring a change of genetic characteristics of the PCR reaction solution, wherein the PCR is carried out by using no an ion-labeled primer; the PCR reaction vessel is a PCR tube or a micro polymerization reaction chamber; the genetic characteristic is impedance, genetic loss, genetic constant or admittance; the electric field is induced by using an alternating current of 1Hz to 100 MHz; and the electric field is induced by using an alternating voltage of 1 mV to 10 V.

    Abstract translation: 目的:提供通过测量电信号检测PCR产物的方法,从而实时检测PCR产物,减少检测系统的大小。 构成:通过测量电信号检测PCR产物的方法包括以下步骤:(a)在PCR反应容器内提供一对电极; (b)进行PCR反应; (c)在电极之间产生电场; 和(d)测量PCR反应溶液的遗传特征的变化,其中通过使用不含离子标记的引物进行PCR; PCR反应容器是PCR管或微聚合反应室; 遗传特征是阻抗,遗传损失,遗传常数或导纳; 通过使用1Hz至100MHz的交流电感应电场; 并且通过使用1mV至10V的交流电压来感应电场。

    경혈점 탐색 장치 및 방법
    33.
    发明公开
    경혈점 탐색 장치 및 방법 失效
    使用平板电极测量局部皮肤电阻的装置和方法

    公开(公告)号:KR1020040036236A

    公开(公告)日:2004-04-30

    申请号:KR1020020065185

    申请日:2002-10-24

    CPC classification number: A61B5/0532

    Abstract: PURPOSE: An apparatus and a method for measuring a local skin resistance using plural electrodes are provided to measure the resistance distribution of a local skin region by using a multi-channel electrode. CONSTITUTION: An apparatus for measuring a local skin resistance using plural electrodes includes a multi-channel electrode(110), a channel selection unit(120), a constant current source(130), a preprocessing unit(140), an A/D converter(150), and a control unit(160). The multi-channel electrode(110) includes a plurality of measuring sensors. The channel selection unit(120) selects channels of the multi-channel electrode in response to a channel control signal of the control unit(160). The constant current source(130) applies the constant current to a measuring target. The preprocessing unit(140) amplifies and filters the measured electric potential values of the channels. The A/D converter(150) is used for converting the electric potential of the preprocessing unit to a digital signal. The control unit(160) processes an output signal of the A/D converter.

    Abstract translation: 目的:提供使用多个电极测量局部皮肤电阻的装置和方法,以通过使用多沟道电极来测量局部皮肤区域的电阻分布。 构成:使用多个电极测量局部皮肤电阻的装置包括多通道电极(110),通道选择单元(120),恒流源(130),预处理单元(140),A / D 转换器(150)和控制单元(160)。 多通道电极(110)包括多个测量传感器。 信道选择单元(120)响应于控制单元(160)的信道控制信号选择多信道电极的信道。 恒流源(130)将恒定电流施加到测量对象。 预处理单元(140)对所测量的通道的电位值进行放大和滤波。 A / D转换器(150)用于将预处理单元的电位转换为数字信号。 控制单元(160)处理A / D转换器的输出信号。

    다챔버 PCR 칩
    34.
    发明公开
    다챔버 PCR 칩 失效
    多台PCR芯片

    公开(公告)号:KR1020030073255A

    公开(公告)日:2003-09-19

    申请号:KR1020020012730

    申请日:2002-03-09

    Abstract: PURPOSE: Provided is a multi chamber PCR chip which processes a large amount of genetic information with a minimized structure and a reduced reaction time. CONSTITUTION: A polynucleotide amplification PCR chip comprises a sample inject domain minutely formed at a solid substrate; a sample flow channel connected to the sample inject domain; PCR performance chambers fluid-communicated with the sample flow channel; a temperature control unit with one or more thin film heaters connected to the top or the bottom of the chambers and one or more temperature sensors connected to the center of the chambers; and adiabatic grooves surrounding the PCR performance chambers.

    Abstract translation: 目的:提供一种多室PCR芯片,其处理大量遗传信息,结构最小化,反应时间缩短。 构成:多核苷酸扩增PCR芯片包含在固体底物上微细形成的样品注入结构域; 连接到样品注入区的样品流动通道; 与样品流通道流体连通的PCR性能室; 具有连接到所述室的顶部或底部的一个或多个薄膜加热器的温度控制单元和连接到所述室的中心的一个或多个温度传感器; 以及围绕PCR性能室的绝热槽。

    칩 상의 전기적 미세 검출기
    35.
    发明公开
    칩 상의 전기적 미세 검출기 失效
    用于检查芯片的微电检测器

    公开(公告)号:KR1020030038084A

    公开(公告)日:2003-05-16

    申请号:KR1020010069502

    申请日:2001-11-08

    CPC classification number: G01N27/44791 G01N27/226 G01N27/4473

    Abstract: PURPOSE: A micro-electric detector for inspecting a surface of a chip is provided to simplify a manufacturing process and to reduce a manufacturing cost by inspecting a micro-channel formed on the surface of the chip using electric and dielectric characteristics of a test sample. CONSTITUTION: A micro-channel(6) is formed on a surface of a first substrate and a detecting section(7) is formed in the micro-channel(6). A second substrate is adjacent to an upper surface of the first substrate formed with the micro-channel(6). At least one pair of single electrodes(8) and interdigit electrodes(9) is formed at a lower surface of the second substrate. The interdigit electrodes(9) are aligned in the same plane with an array pattern. The micro-channel(6) includes an electrophoresis micro-channel.

    Abstract translation: 目的:提供用于检查芯片表面的微电检测器,以简化制造工艺并通过使用测试样品的电和介电特性检查形成在芯片表面上的微通道来降低制造成本。 构成:微通道(6)形成在第一基板的表面上,并且检测部分(7)形成在微通道(6)中。 第二基板与形成有微通道(6)的第一基板的上表面相邻。 在第二基板的下表面上形成至少一对单电极(8)和叉指电极(9)。 叉指电极(9)在阵列图案的同一平面上排列。 微通道(6)包括电泳微通道。

    물질 유로의 측벽에 형성된 MOSFET으로 이루어진물질 검출용 칩, 이를 포함하는 물질 검출 장치, 이의제조 방법 및 물질 검출 장치를 이용한 물질 검출 방법
    36.
    发明公开
    물질 유로의 측벽에 형성된 MOSFET으로 이루어진물질 검출용 칩, 이를 포함하는 물질 검출 장치, 이의제조 방법 및 물질 검출 장치를 이용한 물질 검출 방법 失效
    用于检测材料的芯片,用于检测包含该材料的材料的装置,其制造方法以及使用该材料检测材料的方法

    公开(公告)号:KR1020020082357A

    公开(公告)日:2002-10-31

    申请号:KR1020010021752

    申请日:2001-04-23

    Inventor: 임근배 박진성

    Abstract: PURPOSE: Provided are a chip for detecting material, a device for detecting material containing the same, a producing method thereof, and a method for detecting material using the same, thereby high integration of a sensor can be possible, a probe can be stably adhered on the chip, and the adherence of the probe can be easily confirmed in situ, so that various target materials can be detected using various probes. CONSTITUTION: The chip for detecting material comprises: a semi-conductive board(100); a microline(105) which is formed on the surface of the semi-conductive board(100) and is the pathway of a material; and MOSFET formed on the side wall of the microline, wherein the gate electrode(150G) of MOSFET is made from gold thin film; a material probe having thiol group is adhered on the surface of the gate electrode of MOSFET by a self assembled monolayer method; and the material is a nucleic acid, protein, an enzyme substrate, a supplemental factor or an oligosaccharide.

    Abstract translation: 目的:提供了用于检测材料的芯片,用于检测含有该材料的材料的装置,其制造方法和使用其的材料的检测方法,从而能够高度集成传感器,可以稳定地粘附探针 在芯片上,可以容易地确认探针的粘附性,从而可以使用各种探针检测各种靶材。 构成:用于检测材料的芯片包括:半导电板(100); 微导线(105),其形成在所述半导电板(100)的表面上并且是材料的通路; 和形成在微线侧壁上的MOSFET,其中MOSFET的栅电极(150G)由金薄膜制成; 具有硫醇基的材料探针通过自组装单层法粘附在MOSFET的栅电极的表面上; 并且该材料是核酸,蛋白质,酶底物,补充因子或寡糖。

    강유전체 박막을 이용한 초고밀도 정보 저장 장치
    37.
    发明授权
    강유전체 박막을 이용한 초고밀도 정보 저장 장치 失效
    使用铁电薄膜介质的小型超高密度数据存储系统

    公开(公告)号:KR100331444B1

    公开(公告)日:2002-04-09

    申请号:KR1019990036532

    申请日:1999-08-31

    Abstract: 본발명은강유전체박막위에최소나노미터크기의유전분극을형성/소멸/재형성하여정보를기록하거나독취할수 있는강유전체박막을이용한초소형정보저장장치를기재한다. 본발명에따른강유전체박막을이용한정보저장장치는, 강유전체박막을기록매체로이용하고, 동시에이 기록매체에정보를기록하거나읽기위한헤드로서강유전체박막과접촉되어원자간의척력(반발력)을이용하는접촉 AFM방식으로구동되는캔틸레버탐침을구비하여 100 Gbit/in이상의고밀도정보저장이가능할뿐 만아니라강유전체박막의특성에따라정보의장기간보존이가능하다.

    디퓨져/노즐 펌프
    38.
    发明公开
    디퓨져/노즐 펌프 失效
    DIFFUSER /喷嘴泵

    公开(公告)号:KR1020010046717A

    公开(公告)日:2001-06-15

    申请号:KR1019990050597

    申请日:1999-11-15

    Abstract: PURPOSE: A diffuser/nozzle pump is provided to reduce volumetric loss and mechanical damage to the check valve by preventing back flow of the fluid, while improving energy efficiency by increasing pumping volume. CONSTITUTION: A diffuser/nozzle pump comprises a main body(1) having a chamber(11) with a predetermine volume; a diaphragm arranged within the chamber so as to change the volume of the chamber; an actuator(12) for operating the diaphragm; a suction port(13a) coupled to the main body and which sucks fluid into the chamber; a discharge port(14a) coupled to the main body and which discharge the fluid from the chamber; and first electrodes(133,143) and second electrodes(134,144) arranged alternately at a diffuser(132) of the suction port and a nozzle(142) of the discharge port, and which form an electric field in the fluid flow direction. A fluid inlet hole(13) and a fluid outlet hole(14) are formed beneath the chamber. The fluid inlet hole is coupled with the suction port, and the fluid outlet hole is coupled with the discharge port.

    Abstract translation: 目的:提供扩散器/喷嘴泵,以通过防止流体的逆流来减小止回阀的体积损失和机械损伤,同时通过增加泵送体积来提高能量效率。 构成:扩散器/喷嘴泵包括具有预定体积的腔室(11)的主体(1); 隔膜,其设置在所述室内,以改变所述室的体积; 用于操作隔膜的致动器(12) 吸入口(13a),其联接到所述主体并且将流体吸入所述室中; 排出口(14a),其联接到主体并且从腔室排出流体; 和第一电极(133,143)和第二电极(134,144)交替布置在吸入口的扩散器(132)和排出口的喷嘴(142)之间,并且在流体流动方向上形成电场。 在腔室下方形成流体入口孔(13)和流体出口孔(14)。 流体入口孔与吸入口连接,流体出口孔与排出口相连。

    전계 효과 트랜지스터 채널 구조가 형성된 스캐닝 프로브마이크로스코프의 탐침 및 그 제작 방법
    39.
    发明公开
    전계 효과 트랜지스터 채널 구조가 형성된 스캐닝 프로브마이크로스코프의 탐침 및 그 제작 방법 失效
    具有场效应晶体管通道结构的扫描探针显微镜探测

    公开(公告)号:KR1020010045981A

    公开(公告)日:2001-06-05

    申请号:KR1019990049531

    申请日:1999-11-09

    CPC classification number: G01Q60/30 G11B9/02 G11B9/149 G11B11/007 Y10S977/875

    Abstract: PURPOSE: A probe of a scanning probe microscope(SPM) having a field-effect-transistor(FET) channel structure is provided to form a structure composed of a source, a channel and a drain, by etching a semiconductor substrate such as a single crystal silicon wafer to fabricate a probe structure, and by performing a doping process regarding an inclined etch surface of a tip portion at the end of the probe structure. CONSTITUTION: A probe(210) of a bar type is composed of a semiconductor. The first impurity is doped to a central inclined surface of a V-shaped tip at the end portion of the probe to form a channel region. The second impurity is doped to both inclined surfaces of the V-shaped tip of the end portion of the probe with the channel region as a center.

    Abstract translation: 目的:提供具有场效应晶体管(FET)沟道结构的扫描探针显微镜(SPM)的探针,以形成由源极,沟道和漏极构成的结构,通过蚀刻半导体衬底 晶体硅晶片以制造探针结构,并且通过对探针结构的末端处的尖端部分的倾斜蚀刻表面进行掺杂工艺。 构成:棒状的探针(210)由半导体构成。 第一杂质被掺杂到探针端部处的V形尖端的中心倾斜表面以形成沟道区。 第二杂质被掺杂到以通道区域为中心的探针的端部的V形尖端的两个倾斜表面。

    CPL에 의한 냉각장치
    40.
    发明公开
    CPL에 의한 냉각장치 失效
    冷却装置采用毛细管泵循环

    公开(公告)号:KR1020010045772A

    公开(公告)日:2001-06-05

    申请号:KR1019990049214

    申请日:1999-11-08

    CPC classification number: F28D15/043 H01L23/427 H01L2224/29499

    Abstract: PURPOSE: A cooling apparatus adopting capillary pumped loop(CPL) is provided to reduce size and improved cooling efficiency, while allowing the apparatus to operate without utilizing a power applied from an external source. CONSTITUTION: An apparatus(12) comprises a lower plate having a loop style groove formed at the upper surface of the lower plate; an upper plate coupled to the upper surface of the lower plate so as to close the groove, and which supplies a working fluid flow passage; an evaporator unit(125) arranged at the working fluid flow passage and which has a plurality of evaporation fins(125a) arranged integrally onto the upper or lower plate; and a condenser unit(124) spaced apart from the evaporator unit, and which has a plurality of condensing fins(124a) arranged integrally onto the upper or lower plate.

    Abstract translation: 目的:提供采用毛细管抽气回路(CPL)的冷却装置,以减小尺寸和提高冷却效率,同时允许设备在不利用外部源的功率的情况下运行。 构成:一种装置(12)包括一个下板,该下板在下板的上表面形成有一个环形槽; 上板,其联接到所述下板的上表面,以封闭所述槽,并且提供工作流体流动通道; 蒸发器单元(125),布置在工作流体流动通道处,并且具有多个整体地布置在上板或下板上的蒸发翅片(125a); 和与蒸发器单元间隔开的冷凝器单元(124),并且具有一体地布置在上板或下板上的多个冷凝翅片(124a)。

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