Abstract:
A method and sensor for detecting the binding of probes and target biomolecules by measuring a difference in the shear stress of the biomolecules bound to the surface of the sensor before and after hybridization of the target molecules to the probes, such as nucleic acids or proteins are provided. The shear stress can be measured sensitively and conveniently as an electrical signal without additional fluorescent labeling and without use of expensive additional devices.
Abstract:
PURPOSE: A method for detecting a PCR product by measuring the electrical signal is provided, thereby detecting the PCR product at real time, and reducing the size of the detecting system. CONSTITUTION: A method for detecting a PCR product by measuring the electrical signal comprises the steps of: (a) providing a pair of electrodes within a PCR reaction vessel; (b) conducting the PCR reaction; (c) inducing an electric field between the electrodes; and (d) measuring a change of genetic characteristics of the PCR reaction solution, wherein the PCR is carried out by using no an ion-labeled primer; the PCR reaction vessel is a PCR tube or a micro polymerization reaction chamber; the genetic characteristic is impedance, genetic loss, genetic constant or admittance; the electric field is induced by using an alternating current of 1Hz to 100 MHz; and the electric field is induced by using an alternating voltage of 1 mV to 10 V.
Abstract:
PURPOSE: An apparatus and a method for measuring a local skin resistance using plural electrodes are provided to measure the resistance distribution of a local skin region by using a multi-channel electrode. CONSTITUTION: An apparatus for measuring a local skin resistance using plural electrodes includes a multi-channel electrode(110), a channel selection unit(120), a constant current source(130), a preprocessing unit(140), an A/D converter(150), and a control unit(160). The multi-channel electrode(110) includes a plurality of measuring sensors. The channel selection unit(120) selects channels of the multi-channel electrode in response to a channel control signal of the control unit(160). The constant current source(130) applies the constant current to a measuring target. The preprocessing unit(140) amplifies and filters the measured electric potential values of the channels. The A/D converter(150) is used for converting the electric potential of the preprocessing unit to a digital signal. The control unit(160) processes an output signal of the A/D converter.
Abstract translation:目的:提供使用多个电极测量局部皮肤电阻的装置和方法,以通过使用多沟道电极来测量局部皮肤区域的电阻分布。 构成:使用多个电极测量局部皮肤电阻的装置包括多通道电极(110),通道选择单元(120),恒流源(130),预处理单元(140),A / D 转换器(150)和控制单元(160)。 多通道电极(110)包括多个测量传感器。 信道选择单元(120)响应于控制单元(160)的信道控制信号选择多信道电极的信道。 恒流源(130)将恒定电流施加到测量对象。 预处理单元(140)对所测量的通道的电位值进行放大和滤波。 A / D转换器(150)用于将预处理单元的电位转换为数字信号。 控制单元(160)处理A / D转换器的输出信号。
Abstract:
PURPOSE: Provided is a multi chamber PCR chip which processes a large amount of genetic information with a minimized structure and a reduced reaction time. CONSTITUTION: A polynucleotide amplification PCR chip comprises a sample inject domain minutely formed at a solid substrate; a sample flow channel connected to the sample inject domain; PCR performance chambers fluid-communicated with the sample flow channel; a temperature control unit with one or more thin film heaters connected to the top or the bottom of the chambers and one or more temperature sensors connected to the center of the chambers; and adiabatic grooves surrounding the PCR performance chambers.
Abstract:
PURPOSE: A micro-electric detector for inspecting a surface of a chip is provided to simplify a manufacturing process and to reduce a manufacturing cost by inspecting a micro-channel formed on the surface of the chip using electric and dielectric characteristics of a test sample. CONSTITUTION: A micro-channel(6) is formed on a surface of a first substrate and a detecting section(7) is formed in the micro-channel(6). A second substrate is adjacent to an upper surface of the first substrate formed with the micro-channel(6). At least one pair of single electrodes(8) and interdigit electrodes(9) is formed at a lower surface of the second substrate. The interdigit electrodes(9) are aligned in the same plane with an array pattern. The micro-channel(6) includes an electrophoresis micro-channel.
Abstract:
PURPOSE: Provided are a chip for detecting material, a device for detecting material containing the same, a producing method thereof, and a method for detecting material using the same, thereby high integration of a sensor can be possible, a probe can be stably adhered on the chip, and the adherence of the probe can be easily confirmed in situ, so that various target materials can be detected using various probes. CONSTITUTION: The chip for detecting material comprises: a semi-conductive board(100); a microline(105) which is formed on the surface of the semi-conductive board(100) and is the pathway of a material; and MOSFET formed on the side wall of the microline, wherein the gate electrode(150G) of MOSFET is made from gold thin film; a material probe having thiol group is adhered on the surface of the gate electrode of MOSFET by a self assembled monolayer method; and the material is a nucleic acid, protein, an enzyme substrate, a supplemental factor or an oligosaccharide.
Abstract:
PURPOSE: A diffuser/nozzle pump is provided to reduce volumetric loss and mechanical damage to the check valve by preventing back flow of the fluid, while improving energy efficiency by increasing pumping volume. CONSTITUTION: A diffuser/nozzle pump comprises a main body(1) having a chamber(11) with a predetermine volume; a diaphragm arranged within the chamber so as to change the volume of the chamber; an actuator(12) for operating the diaphragm; a suction port(13a) coupled to the main body and which sucks fluid into the chamber; a discharge port(14a) coupled to the main body and which discharge the fluid from the chamber; and first electrodes(133,143) and second electrodes(134,144) arranged alternately at a diffuser(132) of the suction port and a nozzle(142) of the discharge port, and which form an electric field in the fluid flow direction. A fluid inlet hole(13) and a fluid outlet hole(14) are formed beneath the chamber. The fluid inlet hole is coupled with the suction port, and the fluid outlet hole is coupled with the discharge port.
Abstract:
PURPOSE: A probe of a scanning probe microscope(SPM) having a field-effect-transistor(FET) channel structure is provided to form a structure composed of a source, a channel and a drain, by etching a semiconductor substrate such as a single crystal silicon wafer to fabricate a probe structure, and by performing a doping process regarding an inclined etch surface of a tip portion at the end of the probe structure. CONSTITUTION: A probe(210) of a bar type is composed of a semiconductor. The first impurity is doped to a central inclined surface of a V-shaped tip at the end portion of the probe to form a channel region. The second impurity is doped to both inclined surfaces of the V-shaped tip of the end portion of the probe with the channel region as a center.
Abstract:
PURPOSE: A cooling apparatus adopting capillary pumped loop(CPL) is provided to reduce size and improved cooling efficiency, while allowing the apparatus to operate without utilizing a power applied from an external source. CONSTITUTION: An apparatus(12) comprises a lower plate having a loop style groove formed at the upper surface of the lower plate; an upper plate coupled to the upper surface of the lower plate so as to close the groove, and which supplies a working fluid flow passage; an evaporator unit(125) arranged at the working fluid flow passage and which has a plurality of evaporation fins(125a) arranged integrally onto the upper or lower plate; and a condenser unit(124) spaced apart from the evaporator unit, and which has a plurality of condensing fins(124a) arranged integrally onto the upper or lower plate.