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公开(公告)号：KR1020100087923A
公开(公告)日：2010-08-06
申请号：KR1020090006987
申请日：2009-01-29
Applicant: 삼성전자주식회사
CPC classification number: F16K99/0001 , B01L3/502707 , B01L3/502738 , B01L2400/0406 , B01L2400/0677 , F16K99/0032 , F16K99/004 , F16K2099/008 , F16K2099/0084 , Y10T29/49405 , Y10T137/218 , Y10T137/2196 , Y10T137/2202
Abstract: PURPOSE: A microfluid for a control valve part and a manufacturing method thereof, which can reduce manufacturing costs by simplifying and miniaturizing a structure, are provided to open a channel without giving pressure in a flowing direction of fluid. CONSTITUTION: A microfluid for a control valve part comprises a channel(101), a valve fill(V) and a capillary tube(121). The channel is to transfer the fluid. The valve fill includes the phase change material which is fused in the room temperature. The valve fill closing channel is fused to make the capillary tube flows in. The valve fill is expanded from the sidewall of channel. The capillary tube has a cross section which is smaller than the channel has.
Abstract translation: 目的：提供一种用于控制阀部件的微流体及其制造方法，其可以通过简化和小型化结构来降低制造成本，以在流体的流动方向上施加压力而打开通道。 构成：用于控制阀部件的微流体包括通道（101），阀填充件（V）和毛细管（121）。 通道是传输流体。 阀门填充物包括在室温下熔合的相变材料。 阀填充关闭通道被熔化以使毛细管流入。阀填充从通道的侧壁扩展。 毛细管具有比通道小的横截面。
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公开(公告)号：KR1020090079032A
公开(公告)日：2009-07-21
申请号：KR1020080004951
申请日：2008-01-16
Applicant: 삼성전자주식회사
IPC: G01N35/00
CPC classification number: B01L3/50273 , B01L2200/16 , B01L2300/0803 , B01L2300/0864 , B01L2300/087 , B01L2400/0409 , B01L3/5027
Abstract: A method for loading liquid reagents into a microfluidic device for blood biochemistry analysis is provided to inject a reagent into a microfluidic device in order to enable the reagent to perform a blood biochemistry test automatically. A method for loading liquid reagents into a microfluidic device(100) for blood biochemistry analysis comprises: a first step of injecting a reagent into reaction chambers(A1~9, B1~11) of the microfluidic device; and a second step of freeze-drying the reagent in the state of being injected into the microfluidic device. The reagent represents a liquid reagent. The reagent is concentrated to a predetermined degree and then injected into the several reaction chambers.
Abstract translation: 提供将液体试剂装载到用于血液生物化学分析的微流体装置中的方法，以将试剂注射到微流体装置中，以使试剂能够自动进行血液生物化学测试。 将液体试剂装入用于血液生物化学分析的微流体装置（100）的方法包括：将试剂注入微流体装置的反应室（A1〜9，B1〜11）中的第一步骤; 以及在注射到微流体装置中的状态下将试剂冷冻干燥的第二步骤。 试剂代表液体试剂。 将试剂浓缩至预定的程度，然后注入几个反应室。
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公开(公告)号：KR100763907B1
公开(公告)日：2007-10-05
申请号：KR1020050129584
申请日：2005-12-26
Applicant: 삼성전자주식회사
CPC classification number: B01L3/502707 , B01L2200/12 , B01L2300/0816 , B01L2300/0887 , Y10T156/1052
Abstract: 본 발명은 유체 포트가 형성되어 있는 제1 기판에 접착물질을 코팅하여 접착층을 형성하는 단계; 상기 접착층이 도포된 상기 제1 기판의 상기 접착층이 형성된 표면에 대하여 미세구조가 형성되어 있는 제2 기판을 상기 유체 포트 및 상기 미세구조가 서로 대응되도록 정렬하는 단계; 50℃ 내지 180℃의 온도 범위의 열을 가하여 상기 제1 기판과 제2 기판을 결합시키는 단계를 포함하는, 미세유동 장치의 제조방법 및 그에 의하여 제조된 장치를 제공한다.
미세유동 장치, 접착물질, SU-8-
公开(公告)号：KR1020070073456A
公开(公告)日：2007-07-10
申请号：KR1020060001395
申请日：2006-01-05
Applicant: 삼성전자주식회사
IPC: C12M1/00
Abstract: A pH regulating device is provided to regulate the pH of a solution accurately and easily regardless of difference among samples such as gas generated during electrolysis, and salt concentration of samples. And a method for regulating the pH of the solution using the same device is provided. The pH regulating device comprises: an electrolysis chip(10) receiving a solution to be subject to the pH adjustment and including a chamber, a cathode electrode, and an anode electrode; an electrolysis chip loading portion(11) for loading the electrolysis chip and including an electrolysis chip supporting portion; an electrode contact terminal, and a cover, an input portion(12) in which the electrolysis condition is inputted; a control portion(13) which controls the electrolysis of the electrolysis chip through input of the electrolysis condition; and a display portion(14) which outputs the electrolysis condition and the progress state. The device further comprises a voltage measuring portion(30), an electric current measuring portion(31), an interface portion(34), a power supplying portion(36) and a power control portion(38).
Abstract translation: 提供了一种pH调节装置，无论样品如电解产生的气体和样品的盐浓度之间的差异如何，都能够准确且容易地调节溶液的pH。 并且提供了使用相同装置调节溶液的pH的方法。 pH调节装置包括：电解芯片（10），其接收要进行pH调节的溶液，并且包括室，阴极电极和阳极电极; 用于装载电解芯片并包括电解芯片支撑部分的电解芯片装载部分（11） 电极接触端子和盖子，输入电解条件的输入部分（12）; 控制部，其通过输入所述电解条件来控制所述电解芯片的电解; 以及输出电解条件和进行状态的显示部（14）。 该装置还包括电压测量部分（30），电流测量部分（31），接口部分（34），供电部分（36）和功率控制部分（38）。
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公开(公告)号：KR1020060109254A
公开(公告)日：2006-10-19
申请号：KR1020050082442
申请日：2005-09-05
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/24 , C12N1/20 , C12N7/00 , C12N2509/10
Abstract: A cell separation method by using hydrophobic solid supports is provided to enhance the separation efficiency and rapidness of cells or viruses, and concentrate cells or viruses so as to be used in purification of nucleic acids by using lab-on-a-chip. The cells are separated by contacting the hydrophobic solid support having water contact angle of 70-90 degree with solution containing cells or viruses at pH 2.5-4, wherein the washing step of the hydrophobic solid support bound with cells or viruses is further added; the contacting step is performed under the static or fluidic condition; the hydrophobic solid support has the structure selected from plane, pillar, bead and sieve; and the pillar-structured hydrophobic solid support has an aspect ratio of 1:1 to 20:1, a ratio of pillar height(H) to pillar distance(D) of 1:1 to 25:1, and pillar distance(D) of 5-100 mum.
Abstract translation: 提供了使用疏水性固体支持物的细胞分离方法，以提高细胞或病毒的分离效率和快速性，并且浓缩细胞或病毒，以便通过使用芯片实验室在核酸的纯化中使用。 通过使具有70-90度的水接触角的疏水性固体支持物与pH 2.5-4的含有细胞或病毒的溶液接触来分离细胞，其中进一步加入与细胞或病毒结合的疏水性固体支持物的洗涤步骤; 接触步骤在静态或流体条件下进行; 疏水性固体支持体具有从平面，立柱，珠粒和筛子中选择的结构; 并且柱状结构的疏水性固体支持体的纵横比为1:1〜20:1，柱高（H）与柱距离（D）的比例为1：1〜25：1，柱距（D） 5-100 mum。
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Patent Agency Ranking
公开(公告)号：KR100624452B1
公开(公告)日：2006-09-18
申请号：KR1020040109272
申请日：2004-12-21
Applicant: 삼성전자주식회사
IPC: C12N15/10
CPC classification number: C07H21/04
Abstract: 본 발명은 기판 상에 작용기를 갖는 히드로겔 또는 PEG-히드로겔 공중합체를 고정화하는 단계; 상기 히드로겔 또는 PEG-히드로겔 공중합체가 고정된 기판에 염과 핵산이 포함된 시료의 혼합 용액을 첨가하여 상기 핵산을 상기 히드로겔 또는 PEG-히드로겔 공중합체에 결합시키는 단계; 상기 핵산이 결합된 히드로겔 또는 PEG-히드로겔 공중합체를 세정하는 단계; 및 용출 용매를 사용하여 상기 결합된 핵산을 용출시키는 단계를 포함하는 고정화된 히드로겔 또는 PEG-히드로겔 공중합체를 이용한 핵산의 분리 및 정제 방법에 관한 것이다. 본 발명에 따르면 히드로겔 또는 PEG-히드로겔 공중합체를 기판 상에 고정화하여 기판 상에서 DNA를 분리, 정제하는 경우 별도의 화학물질의 첨가 없이 DNA를 결합 및 용출시키고, PCR 과 같은 후속 공정에 대한 영향을 최소화할 수 있으며, PEG 농도 조절에 따라 결합되는 DNA의 양 및 결합의 세기를 조절할 수 있으며, 히드로겔 형태의 화합물이 기판 상에 존재하기 때문에 패터닝이 가능하다.
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公开(公告)号：KR1020060069235A
公开(公告)日：2006-06-21
申请号：KR1020050066353
申请日：2005-07-21
Applicant: 삼성전자주식회사
IPC: C12M1/42
Abstract: Provided are a microfluidic device including an electrolysis device for cell lysis which includes an anode chamber, a cathode chamber and a separator, in which the separator is installed between the anode chamber and the cathode chamber, the anode chamber includes an inlet and an outlet for an anode chamber solution and an electrode, and the cathode chamber includes an inlet and an outlet for a cathode chamber solution and an electrode, and a method of electrochemically lysing cells using the same.
Abstract translation: 提供了一种微流体装置，其包括用于细胞裂解的电解装置，其包括阳极室，阴极室和隔板，其中隔膜安装在阳极室和阴极室之间，阳极室包括入口和出口 阳极室溶液和电极，阴极室包括用于阴极室溶液和电极的入口和出口，以及使用其进行电化学裂解细胞的方法。
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公开(公告)号：KR1020120113533A
公开(公告)日：2012-10-15
申请号：KR1020110031285
申请日：2011-04-05
CPC classification number: B01L3/502746 , B01L3/502753 , B01L2200/0652 , B01L2300/0816 , B01L2300/123 , B01L2400/0655 , B01L2400/086
Abstract: PURPOSE: A target molecular separating apparatus and a target molecular separating method using the same are provided to separate target molecules without external force and to control the cut off sizes of the separated target molecules. CONSTITUTION: A target molecular separating method includes the following steps: a fluid inlet(110) is arranged at one side of a substrate(10) made of elastomer; fluid containing at least one kinds of target molecules is injected into the fluid inlet; a fluid channel part(120) is connected to the fluid inlet, and a plurality of protruded parts is formed at the first sidewall of the fluid channel part; the flow of the fluid is controlled by the fluid channel part with variable heights, and target molecular are separated by sizes; and a fluid outlet is connected to the fluid channel part, and the fluid containing the separated target molecules is drained through the fluid outlet.
Abstract translation: 目的：提供目标分子分离装置和使用其的目标分子分离方法以在没有外力的情况下分离目标分子并控制分离的目标分子的切断大小。 构成：目标分子分离方法包括以下步骤：流体入口（110）布置在由弹性体制成的基底（10）的一侧; 含有至少一种靶分子的流体被注入到流体入口中; 流体通道部分（120）连接到流体入口，并且多个突出部分形成在流体通道部分的第一侧壁处; 流体的流动由具有可变高度的流体通道部分控制，并且靶分子通过尺寸分开; 并且流体出口连接到流体通道部分，并且包含分离的目标分子的流体通过流体出口排出。
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公开(公告)号：KR1020110108177A
公开(公告)日：2011-10-05
申请号：KR1020100027537
申请日：2010-03-26
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/6806 , C12Q2521/301
Abstract: 표적 핵산의 제조 방법에 관한 것이다. 일 구체예에 따른 표적 핵산의 제조 방법에 따르면, 마이크로어레이와 같은 바이오 칩에 사용될 수 있는 표적 핵산을 효율적으로 제조할 수 있다.
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