입자 부분 노출형 기재 및 그 제조방법
    31.
    发明公开
    입자 부분 노출형 기재 및 그 제조방법 有权
    颗粒暴露基板及其制造方法

    公开(公告)号:KR1020150136923A

    公开(公告)日:2015-12-08

    申请号:KR1020140064652

    申请日:2014-05-28

    Inventor: 김재호 김효섭

    CPC classification number: B05C19/00 B05D7/02 B82B3/00 C23C24/02

    Abstract: 본실시예에따른입자코팅기재의제조방법은, 밀착성고분자기판을준비하는준비단계; 상기밀착성고분자기판위에복수의입자를코팅하는코팅단계; 상기밀착성고분자기판및 상기복수의입자위에기재를형성하는단계; 및상기밀착성고분자기판을제거하여상기복수의입자를부분적으로노출하는노출단계를포함한다.

    Abstract translation: 本实施方式的粒子被覆基材的制造方法包括:准备粘合性聚合物基材的准备工序; 在粘合剂聚合物基底上涂覆多个颗粒的涂覆步骤; 在粘合剂聚合物基材和多个颗粒上形成基材; 以及通过除去粘合剂聚合物基材而部分暴露多个颗粒的曝光步骤。

    입자 정렬을 이용한 코팅 방법 및 이에 의해 제조된 입자 코팅 기판
    32.
    发明公开
    입자 정렬을 이용한 코팅 방법 및 이에 의해 제조된 입자 코팅 기판 有权
    使用由其制造的颗粒对准和颗粒涂层基材的涂布方法

    公开(公告)号:KR1020140069639A

    公开(公告)日:2014-06-10

    申请号:KR1020120137171

    申请日:2012-11-29

    Inventor: 김재호 김효섭

    Abstract: A coating method using a particle alignment according to an embodiment of the present invention comprises: a preparation method of preparing an adhesive polymer substrate having a smooth surface; and a coating step of coating multiple particles by applying pressure on multiple particles on the smooth surface of the adhesive polymer substrate, forming multiple concave parts corresponding to the multiple particles on the smooth surface of the adhesive polymer substrate and reinforcing the bonding property between the multiple particles and the adhesive polymer substrate.

    Abstract translation: 根据本发明实施方案的使用粒子对准的涂布方法包括:制备具有光滑表面的粘合剂聚合物基材的制备方法; 以及涂布步骤,通过对粘合剂聚合物基材的光滑表面上的多个颗粒施加压力来涂覆多个颗粒,形成与粘合剂聚合物基材的光滑表面上的多个颗粒相对应的多个凹部,并增强多个颗粒之间的粘合性能 颗粒和粘合剂聚合物基材。

    바이오 센서용 광학 표지자, 이를 포함하는 광학 바이오센서 및 상기 바이오 센서용 광학 표지자의 제조방법
    35.
    发明公开
    바이오 센서용 광학 표지자, 이를 포함하는 광학 바이오센서 및 상기 바이오 센서용 광학 표지자의 제조방법 有权
    用于生物传感器的光学标记物,包含其的光学生物传感器以及用于生产用于生物传感器的光学标记物的方法

    公开(公告)号:KR1020170075221A

    公开(公告)日:2017-07-03

    申请号:KR1020150184599

    申请日:2015-12-23

    Abstract: 목적생체물질과선택적으로결합하고, 입사광을재귀반사시키는바이오센서용광학표지자가개시된다. 광학표지자는투명한코어입자, 코어입자표면의일부를피복하고코어입자보다굴절률이작은물질로형성된전반사유도층, 전반사유도층상에형성된수식층및 수식층에결합되고목적생체물질과선택적으로결합하는생체인지물질을구비한다. 이러한광학표지자는비분광광원및 분광광원모두에대해서우수한광학표지자로서기능할수 있다.

    Abstract translation: 公开了一种用于选择性结合目标生物材料并回射入射光的生物传感器的光学标记。 光学盖的透明核粒子的活体,覆盖中心粒子表面的一部分,并且被耦合到形成在全反射诱导层的公式层和式层,更小的折射率的材料形成全反射衍生层比芯粒子选择性地耦合到所述对象的生物材料 认知材料。 这种光学标记可以用作非光谱和光谱光源的优异光学标记。

    마이크로미터 수준 입자의 함침율 조절방법 및 이에 의해 제조된 입자 코팅 기판
    36.
    发明公开
    마이크로미터 수준 입자의 함침율 조절방법 및 이에 의해 제조된 입자 코팅 기판 有权
    控制微乳液颗粒和颗粒涂层底物的印迹方法

    公开(公告)号:KR1020150137198A

    公开(公告)日:2015-12-09

    申请号:KR1020140064505

    申请日:2014-05-28

    Abstract: 밀착성고분자기판에경화제(1차경화제)를포함시켜혼합한밀착성고분자기판을투액성기판에도포하는단계; 상기투액성기판상에위치한밀착성고분자기판상에입자를위치시키는단계; 상기입자를밀착성고분자기판의표면에입자를코팅하는단계; 코팅된입자와밀착성고분자층의결합력을향상시키기위해입자가코팅된기판을공기분위기하에서 UV를조사시키는단계; 경화제(2차경화제)를용기상에도포하는단계; 상기입자가코팅된밀착성고분자기판뒷면의투액성기판을상기용기상에위치시켜경화제(2차경화제)를흡수시키는단계로이루어진마이크로미터수준입자의함침율향상방법이개시된다.

    Abstract translation: 本发明公开了一种改善微米级粒子浸渍的方法,其特征在于,包括以下步骤:通过在粘合性聚合物基材上含有固化剂(一次固化剂)在透水性基材上涂布粘合剂聚合物基材; 将颗粒定位在位于透水性基材上的粘合剂聚合物基材上; 在粘合剂聚合物基材的表面上涂覆颗粒; 在空气条件下在颗粒涂覆的基材上辐射UV以改善涂覆颗粒和粘合剂聚合物层的粘附性; 在容器上涂覆固化剂(二次固化剂); 并通过将透水性基材放置在涂覆有颗粒的粘合剂聚合物基材的背面上来吸收固化剂(二次固化剂)。

    입자 정렬을 이용한 코팅 방법 및 이에 의해 제조된 입자 코팅 기판
    37.
    发明公开
    입자 정렬을 이용한 코팅 방법 및 이에 의해 제조된 입자 코팅 기판 审中-实审
    使用由其制造的颗粒对准和颗粒涂层基材的涂布方法

    公开(公告)号:KR1020140070334A

    公开(公告)日:2014-06-10

    申请号:KR1020130079982

    申请日:2013-07-08

    Inventor: 김재호 김효섭

    CPC classification number: B05D7/02 B05D2201/02 B82Y40/00 C23C24/02

    Abstract: A coating method using particle alignment according to an embodiment of the present invention comprises: a preparing step for preparing a cohesive polymer substrate having a smooth surface; and a coating step for coating the smooth surface of the cohesive polymer substrate with a plurality of particles while forming recess parts respectively corresponding to the particles on the smooth surface of the cohesive polymer substrate by pressing the particles to the cohesive polymer substrate, so that binding properties between the particles and the cohesive polymer substrate are enhanced.

    Abstract translation: 根据本发明实施方案的使用粒子排列的涂布方法包括:制备具有光滑表面的粘合聚合物基材的制备步骤; 以及涂布步骤,用多个颗粒涂布粘合聚合物基材的光滑表面,同时通过将颗粒压在粘合性聚合物基材上,形成分别对应于粘合聚合物基材的光滑表面上的颗粒的凹部,从而结合 增强了颗粒与内聚聚合物底物之间的性能。

    나노입자의 독성 평가방법
    38.
    发明公开
    나노입자의 독성 평가방법 有权
    纳米粒子的毒性评估方法

    公开(公告)号:KR1020140013390A

    公开(公告)日:2014-02-05

    申请号:KR1020120080204

    申请日:2012-07-23

    Abstract: The present invention relates to a method for evaluating toxicity of nanoparticles, and more particularly, to a method for evaluating toxicity of nanoparticles comprising the steps of: obtaining a sample of tissues or cells of a mammal exposed to nanoparticles; irradiating at least one selected from a group consisting of a glutamic acid content, a pyruvate content, whether mitochondria within a cell is damages or not, a reactive oxygen species (ROS) content and an ATP content within the sample; comparing with a control group. The method for evaluating toxicity of nanoparticles according to the present invention analyzes factors having high a correlation with the toxicity of nanoparticles. By using this, it is possible to more precisely detect the toxicity of nanoparticles with excellent detection sensitivity, and through this, it can be effectively used in monitoring or evaluating harmfulness of the toxicity of nanoparticles, as well as effectively used as a tool for examining various diseases, the effects on health or the like when exposed to nanoparticles.

    Abstract translation: 本发明涉及一种用于评价纳米颗粒的毒性的方法,更具体地,涉及一种用于评估纳米颗粒毒性的方法,包括以下步骤:获得暴露于纳米颗粒的哺乳动物的组织或细胞样品; 照射来自由谷氨酸含量,丙酮酸含量组成的组中的至少一种,细胞内的线粒体是否损伤,样品中的活性氧(ROS)含量和ATP含量; 与对照组比较。 根据本发明的纳米颗粒的毒性评估方法分析与纳米颗粒的毒性高度相关的因素。 通过使用这种方法,可以更精确地检测具有优异检测灵敏度的纳米颗粒的毒性,通过这种方法,可以有效地用于监测或评估纳米颗粒毒性的有害性,并有效地用作检查的工具 各种疾病,当暴露于纳米颗粒时对健康等的影响。

    미세구조의 세포배양 기판
    39.
    发明公开
    미세구조의 세포배양 기판 有权
    细胞培养的细微结构基质

    公开(公告)号:KR1020130043921A

    公开(公告)日:2013-05-02

    申请号:KR1020110108110

    申请日:2011-10-21

    CPC classification number: C12M23/04 C12M23/20 C12N5/0655 C12N5/0662

    Abstract: PURPOSE: A cell culture substrate of a fine structure is provided to control the growth and differentiation of a cell, and to overcome a dedifferentiation phenomenon of chondrocyte cultivation through a special structure design of the culture substrate. CONSTITUTION: A cell culture substrate comprises a thin film in which fine particles are arranged. The surface characteristics of the cell culture substrate obtained with the arrangement of the spherical fine particles satisfy the following: surface roughness(Rq)

    Abstract translation: 目的:提供细胞结构的细胞培养底物,以控制细胞的生长和分化,并通过培养基质的特殊结构设计克服软骨细胞培养的去分化现象。 构成:细胞培养基材包括其中布置细颗粒的薄膜。 通过配置球状微粒而获得的细胞培养基的表面特性满足以下:表面粗糙度(Rq)<= 0.13D(细颗粒的平均粒径)。 细颗粒的平均粒径在250纳米-10微米的范围内。 细颗粒的平均粒径在300纳米-3微米的范围内。 表面粗糙度为25纳米-1000纳米,表面高差为170纳米-10微米。

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