엔테로코커스 패칼리스 시알엔비-에이3을 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물
    37.
    发明公开
    엔테로코커스 패칼리스 시알엔비-에이3을 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물 有权
    包含用于治疗或预防原发性胆汁淤积的生物化学CRNB-A3的发酵金山提取物的组合物

    公开(公告)号:KR1020130122067A

    公开(公告)日:2013-11-07

    申请号:KR1020120045102

    申请日:2012-04-30

    Inventor: 남명수 송규용

    CPC classification number: A61K36/258 A23L19/00 A23L33/10 A61K35/747

    Abstract: The present invention relates to a composition containing an extract of fermented ginseng using Enterococcus faecalis CRNB-A3 (accession number KCTC 11930BP) for preventing or treating atopic dermatitis. The composition effectively suppresses the activities of monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), and interleukin-6 (IL-6), thereby being used as a therapeutic agent which treats or alleviates symptoms of various skin disorders such as atopic dermatitis. [Reference numerals] (AA) Normal group;(BB) Mite extract;(CC) Dexamethasone;(DD) Example 3-1;(EE) Example 3-2;(FF) Example 3-3;(GG) Comparative example 1-1;(HH) Comparative example 1-2;(II) Comparative example 2-1;(JJ) Comparative example 2-2

    Abstract translation: 本发明涉及含有用于预防或治疗特应性皮炎的发酵人参提取物的组合物,其使用粪肠球菌CRNB-A3(登录号KCTC 11930BP)。 该组合物有效抑制单核细胞趋化蛋白-1(MCP-1),白细胞介素-8(IL-8)和白细胞介素-6(IL-6)的活性,从而被用作治疗或缓解 各种皮肤疾病如特应性皮炎。 实施例3-1;(EE)实施例3-2;(FF)实施例3-3;(GG)比较例(AA)正常组;(BB)螨提取物;(CC)地塞米松; 1-1;(HH)比较例1-2;(II)比较例2-1;(JJ)比较例2-2

    락토바실러스 플랜타럼 시알엔비-22를 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물
    38.
    发明公开
    락토바실러스 플랜타럼 시알엔비-22를 이용한 발효인삼의 추출물을 함유하는 아토피 피부염의 예방 또는 치료용 조성물 有权
    一种包含使用植物乳杆菌CRNB-22处理或预防原生质体的发酵金山提取物的组合物

    公开(公告)号:KR1020130122066A

    公开(公告)日:2013-11-07

    申请号:KR1020120045101

    申请日:2012-04-30

    Inventor: 남명수 송규용

    CPC classification number: A61K36/258 A23L19/00 A23L33/10 A61K35/747 C12R1/25

    Abstract: The present invention relates to a composition containing an extract of fermented ginseng using Lactobacillus plantarum CRNB-22 (accession number KCTC 11931BP) for preventing or treating atopic dermatitis. The composition effectively suppresses the activities of monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), and interleukin-6 (IL-6), thereby being used as a therapeutic agent for treating or relieving symptoms of various skin disorders such as atopic dermatitis. [Reference numerals] (AA) Normal bacteria;(BB) Mite extract;(CC) Dexamethasone;(DD) Example 3-1;(EE) Example 3-2;(FF) Example 3-3;(GG) Comparative example 1-1;(HH) Comparative example 1-2;(II) Comparative example 2-1;(JJ) Comparative example 2-2

    Abstract translation: 本发明涉及含有用于预防或治疗特应性皮炎的植物乳杆菌CRNB-22(登录号KCTC 11931BP)的发酵人参提取物的组合物。 该组合物有效抑制单核细胞趋化蛋白-1(MCP-1),白细胞介素-8(IL-8)和白细胞介素-6(IL-6)的活性,从而用作治疗或缓解症状的治疗剂 各种皮肤疾病如特应性皮炎。 实施例3-1;(EE)实施例3-2;(FF)实施例3-3;(GG)比较例(AA)正常细菌;(BB)螨提取物;(CC)地塞米松; 1-1;(HH)比较例1-2;(II)比较例2-1;(JJ)比较例2-2

    신나모일살리실아미드 유도체 또는 이의 약학적으로 허용 가능한 그의 염을 유효성분으로 함유하는 암질환 치료 및 예방용 조성물
    39.
    发明公开
    신나모일살리실아미드 유도체 또는 이의 약학적으로 허용 가능한 그의 염을 유효성분으로 함유하는 암질환 치료 및 예방용 조성물 有权
    包含新戊酰胺衍生物的组合物或其治疗或预防癌症疾病的药物可接受的盐

    公开(公告)号:KR1020120136762A

    公开(公告)日:2012-12-20

    申请号:KR1020110055907

    申请日:2011-06-10

    Inventor: 송규용 오상택

    Abstract: PURPOSE: A composition containing cinnamoylsalcylamide derivatives and pharmaceutically acceptable salts thereof is provided to strongly suppress Wint signal transduction and to prevent and treat cancer. CONSTITUTION: A pharmaceutical composition for preventing and treating cancer contains cinnamoylsalcylamide derivatives of general formula I, II, or III, or pharmaceutically acceptable salts thereof as an active ingredient. The cinnamoylsalcylamide derivative is an N-[3-benzo[1,3]deoxole-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ13) compound group or an N-[3-thiophene-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ24) compound group. A Wint signal transduction inhibitor contains the cinnamoylsalcylamide derivative or salts as an active ingredient.

    Abstract translation: 目的:提供含有肉桂酰硫代酰胺衍生物及其药学上可接受的盐的组合物以强烈抑制Wint信号转导并预防和治疗癌症。 构成:用于预防和治疗癌症的药物组合物含有通式I,II或III的肉桂酰基硫代酰胺衍生物或其药学上可接受的盐作为活性成分。 肉桂酰基硫代酰胺衍生物是N- [3-苯并[1,3]脱氧-1-氧代-2-苯基] -2-羟基苯甲酰胺(YJ13)化合物或N- [3-噻吩-1-氧代-2- 苯基] -2-羟基苯甲酰胺(YJ24)化合物。 Wint信号转导抑制剂含有肉桂酰基硫代酰胺衍生物或其盐作为活性成分。

    인삼 발효능을 갖는 신규 락토바실러스 플랜타럼 CRNB―22 〔KCTC11931 BP〕균주 및 이를 이용한 사포닌 전환 방법
    40.
    发明公开
    인삼 발효능을 갖는 신규 락토바실러스 플랜타럼 CRNB―22 〔KCTC11931 BP〕균주 및 이를 이용한 사포닌 전환 방법 有权
    新型植物乳杆菌CRNB-22 KCTC 11931能够发酵人参的BP菌株及使用其转化皂苷的方法

    公开(公告)号:KR1020120125113A

    公开(公告)日:2012-11-14

    申请号:KR1020110043207

    申请日:2011-05-06

    Inventor: 남명수 송규용

    Abstract: PURPOSE: A novel Lactobacillus plantarum CRNB-22 strain with a saponin decomposition ability and a method for decomposing saponin using the same are provided to prepare ginseng and red ginseng fermentations. CONSTITUTION: A Lactobacillus plantarum CRNB-22(KCTC 11931 BP) strain has a saponin converting ability. The strain is used for converting saponin Rb1 into other ginsenoside. A method for preparing fermented ginseng comprises a step of inoculating ginseng with the strain and a step of fermenting at 20-50 Deg. C. for 20-120 hours. A health functional food contains the fermented ginseng. A pharmaceutical composition for preventing or treating inflammation, allergy, cancer, impotency, hypertension, hyperlipidemia, or aging contains the fermented ginseng.

    Abstract translation: 目的:提供一种具有皂角苷分解能力的新型植物乳杆菌CRNB-22菌株和使用其分解皂苷的方法,以制备人参和红参发酵。 构成:植物乳酸乳杆菌CRNB-22(KCTC 11931 BP)菌株具有皂角苷转化能力。 该菌株用于将皂苷Rb1转化为其他人参皂甙。 制备发酵人参的方法包括用该菌株接种人参的步骤和在20-50度发酵的步骤。 C. 20-120小时。 保健功能食品含有发酵人参。 用于预防或治疗炎症,过敏,癌症,阳ency,高血压,高脂血症或衰老的药物组合物含有发酵人参。

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