Abstract:
The present invention relates to a composition containing an extract of fermented ginseng using Enterococcus faecalis CRNB-A3 (accession number KCTC 11930BP) for preventing or treating atopic dermatitis. The composition effectively suppresses the activities of monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), and interleukin-6 (IL-6), thereby being used as a therapeutic agent which treats or alleviates symptoms of various skin disorders such as atopic dermatitis. [Reference numerals] (AA) Normal group;(BB) Mite extract;(CC) Dexamethasone;(DD) Example 3-1;(EE) Example 3-2;(FF) Example 3-3;(GG) Comparative example 1-1;(HH) Comparative example 1-2;(II) Comparative example 2-1;(JJ) Comparative example 2-2
Abstract:
The present invention relates to a composition containing an extract of fermented ginseng using Lactobacillus plantarum CRNB-22 (accession number KCTC 11931BP) for preventing or treating atopic dermatitis. The composition effectively suppresses the activities of monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), and interleukin-6 (IL-6), thereby being used as a therapeutic agent for treating or relieving symptoms of various skin disorders such as atopic dermatitis. [Reference numerals] (AA) Normal bacteria;(BB) Mite extract;(CC) Dexamethasone;(DD) Example 3-1;(EE) Example 3-2;(FF) Example 3-3;(GG) Comparative example 1-1;(HH) Comparative example 1-2;(II) Comparative example 2-1;(JJ) Comparative example 2-2
Abstract:
PURPOSE: A composition containing cinnamoylsalcylamide derivatives and pharmaceutically acceptable salts thereof is provided to strongly suppress Wint signal transduction and to prevent and treat cancer. CONSTITUTION: A pharmaceutical composition for preventing and treating cancer contains cinnamoylsalcylamide derivatives of general formula I, II, or III, or pharmaceutically acceptable salts thereof as an active ingredient. The cinnamoylsalcylamide derivative is an N-[3-benzo[1,3]deoxole-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ13) compound group or an N-[3-thiophene-1-oxo-2-prophenyl]-2-hydroxybenzamide(YJ24) compound group. A Wint signal transduction inhibitor contains the cinnamoylsalcylamide derivative or salts as an active ingredient.
Abstract:
PURPOSE: A novel Lactobacillus plantarum CRNB-22 strain with a saponin decomposition ability and a method for decomposing saponin using the same are provided to prepare ginseng and red ginseng fermentations. CONSTITUTION: A Lactobacillus plantarum CRNB-22(KCTC 11931 BP) strain has a saponin converting ability. The strain is used for converting saponin Rb1 into other ginsenoside. A method for preparing fermented ginseng comprises a step of inoculating ginseng with the strain and a step of fermenting at 20-50 Deg. C. for 20-120 hours. A health functional food contains the fermented ginseng. A pharmaceutical composition for preventing or treating inflammation, allergy, cancer, impotency, hypertension, hyperlipidemia, or aging contains the fermented ginseng.