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    크립토탄시논을 유효성분으로 포함하는 안압 하강용 조성물
    31.
    发明公开
    크립토탄시논을 유효성분으로 포함하는 안압 하강용 조성물 无效
    一种用于降低眼内压的组合物，其包含隐丹参酮作为活性成分

    公开(公告)号：KR1020170076105A

    公开(公告)日：2017-07-04

    申请号：KR1020150185947

    申请日：2015-12-24

    Applicant: 한국과학기술연구원

    Inventor： 정상훈 ,  안홍열 ,  권만재 ,  김경아 ,  강석우

    IPC: A61K31/343 ,  A23L1/30

    Abstract: 본명세서에는크립토탄시논(Cryptotanshinone), 이의염, 이의프로드럭, 이의수화물, 이의용매화물또는이의이성질체를유효성분으로포함하는안압하강용조성물이개시된다. 상기크립토탄시논은종래안압강하제의두통, 피로또는흉부통과같은부작용이없이안압을낮추거나안압을정상수치로조절함으로써고안압증, 녹내장을예방, 개선또는치료하는효과가있다.

    Abstract translation: 本文公开了一种用于降低眼内压的组合物，其包含隐丹参酮，其盐，其前药，其水合物，其溶剂合物或其异构体作为活性成分。 当加密碳非具有预防，改善或通过控制在现有技术头痛，疲劳的眼压降低剂或降低眼内压而没有副作用如胸部传球或眼内压在正常水平治疗高眼压和青光眼的效果。

    산채류 추출물을 유효성분으로 함유하는 염증성 질환 예방 또는 치료용 조성물
    35.
    发明公开
    산채류 추출물을 유효성분으로 함유하는 염증성 질환 예방 또는 치료용 조성물 有权
    预防和治疗含有野生植物提取物作为活性成分的炎症性疾病的组合物

    公开(公告)号：KR1020100073553A

    公开(公告)日：2010-07-01

    申请号：KR1020080132264

    申请日：2008-12-23

    Applicant: 한국과학기술연구원

    Inventor： 판철호 ,  차광현 ,  구송이 ,  송대근 ,  노주원 ,  정상훈 ,  엄병헌 ,  김철영 ,  이은하 ,  이희주 ,  강석우 ,  이샛별 ,  강경수 ,  유지혜 ,  김명수 ,  이재권 ,  안수용 ,  김종환

    IPC: A61K36/896 ,  A61P29/00

    Abstract: PURPOSE: A composition containing plant extracts for preventing or treating inflammatory diseases is provided to suppress No and prostaglandin E2(PGE2) generations without cytotoxicity. CONSTITUTION: A pharmaceutical composition contains Philadelphus schrenkii Rup. var. schnenkii or Allium microdictyon Prokh extract as an active ingredient. The extract is isolated using water, C1-C4 low alcohol, or mixture thereof. The low alcohol is methanole or ethanol. Inflammatory disease is used for treating and preventing by administering Philadelphus schrenkii Rup. var. schnenkii or Allium microdictyon Prokh extract in the amount of suppressing inflammation. A health food composition of functional feed composition contiains Philadelphus schrenkii Rup. var. schnenkii or Allium microdictyon Prokh extract as an active ingredient.

    Abstract translation: 目的：提供含有用于预防或治疗炎性疾病的植物提取物的组合物，以抑制No和前列腺素E2（PGE2）代而不具有细胞毒性。 宪法：药物成分包含费城schrenkii Rup。 变种。 Schnenkii或Allium microdictyon Prokh提取物作为活性成分。 使用水，C1-C4低级醇或其混合物分离提取物。 低级醇是甲醇或乙醇。 炎症性疾病用于治疗和预防费城费伦基隆。 变种。 Schnenkii或Allium microdictyon Prokh提取物中抑制炎症的量。 功能性饲料成分的保健食品组合物包括费城schrenkii Rup。 变种。 Schnenkii或Allium microdictyon Prokh提取物作为活性成分。

    채찍말 추출물을 포함하는 화학적 암 예방을 위한 식품 조성물
    37.
    发明授权
    채찍말 추출물을 포함하는 화학적 암 예방을 위한 식품 조성물 失效
    包含CUTLERIA CYLINDRICA提取物的癌症化学成分的食品组合物

    公开(公告)号：KR100850475B1

    公开(公告)日：2008-08-07

    申请号：KR1020070027571

    申请日：2007-03-21

    Applicant: 한국과학기술연구원

    Inventor： 판철호 ,  이샛별 ,  김민철 ,  엄병헌 ,  이은하 ,  이주영 ,  노주원 ,  정상훈

    IPC: A61K36/25 ,  A61P35/00

    Abstract: A food composition comprising the extract of Cutleria cylindrical is provided to improve cancer chemoprevention by inducing activity of quinone reductase as a marker enzyme of cancer prevention and cause no toxicity to human cells. A food composition for cancer chemoprevention comprises 0.001-99.9 wt.% based on the total weight of food, or 0.001-0.1g, preferably 0.05-0.1g in 100 ml of drink of the extract of Cutleria cylindrical which is prepared by extracting Cutleria cylindrical with water or organic solvent such as ethanol, and is formulated as chewing gum, caramel, candy, ice cream, confectionaries, drink, mineral water, alcohol drink, or vitamin- or mineral-containing food.

    Abstract translation: 提供包含圆锥形切片的提取物的食物组合物，以通过诱导醌还原酶的活性作为预防癌症的标记酶而引起对人体细胞毒性的改善来改善癌症化学预防。 用于癌症化学预防的食物组合物包含基于食物总重量的0.001-99.9重量％，或0.001-0.1g，优选0.05-0.1g，在100毫升卷心菜提取物的饮料中，其通过提取Cutleria圆柱形 配合水或有机溶剂如乙醇，并配制成口香糖，焦糖，糖果，冰淇淋，糖果，饮料，矿泉水，酒精饮料或维生素或矿物质食品。

    초고압(Ｈｉｇｈ ｈｙｄｒｏｓｔａｔｉｃｐｒｅｓｓｕｒｅ)을 이용하여 오죽잎으로부터 항산화활성물질을 추출하는 방법
    38.
    发明授权
    초고압(Ｈｉｇｈ ｈｙｄｒｏｓｔａｔｉｃｐｒｅｓｓｕｒｅ)을 이용하여 오죽잎으로부터 항산화활성물질을 추출하는 방법 有权
    提取天然抗氧化剂的方法，用于提取高效液相色谱法

    公开(公告)号：KR100847806B1

    公开(公告)日：2008-07-23

    申请号：KR1020070028741

    申请日：2007-03-23

    Applicant: 한국과학기술연구원

    Inventor： 차광현 ,  이동언 ,  엄병헌 ,  김철영 ,  정상훈 ,  판철호 ,  이희주 ,  이은하

    IPC: A61K8/97 ,  A61Q19/08

    CPC classification number: A61K8/97 ,  A23L33/105 ,  A61K36/899 ,  A61K2236/37 ,  A61K2800/522

    Abstract: A method for extraction of leaves of Phyllostachys nigra is provided to prevent destruction of natural antioxidants and improve extraction yield by using high hydrostatic pressure without heat treatment, and inhibit environment pollution by using water as solvent. A method for extraction of leaves of Phyllostachys nigra comprises the steps of: (a) adding water into the dried leaves of Phyllostachys nigra; (b) inserting the water added leaves of Phyllostachys nigra into a high hydrostatic pressure device and treating it under the pressure of 200MPa or more for 1-3 minutes; and (c) leaving the pressure-treated leaves of Phyllostachys nigra at room temperature to extract antioxidants from the leaves of Phyllostachys nigra. A cosmetic composition contains the antioxidants extracted from the leaves of Phyllostachys nigra and is formulated as soap, lotion, cream, pack or solution. Further, a step of hydrating the leaves of Phyllostachys nigra is additionally comprised between the step (a) and the step (b) in the method.

    Abstract translation: 提供黑叶提取方法，以防止天然抗氧化剂的破坏，并且通过使用高温静压不经热处理提高提取率，并通过使用水作为溶剂来抑制环境污染。 一种黑叶提取叶片的方法，包括以下步骤：（a）将黑麦黑叶子的叶子加入水中; （b）将黑曲霉加入的叶片插入高静水压装置中，在200MPa或更高的压力下处理1-3分钟; 和（c）将黑曲霉的加压处理的叶离开室温以从黑木叶中提取抗氧化剂。 化妆品组合物含有从黑叶木叶提取的抗氧化剂，并配制成肥皂，洗剂，霜剂，包装或溶液。 此外，在该方法中的步骤（a）和步骤（b）之间还包括水分黑木叶子的步骤。

    숙취 해소 및 항산화 활성을 가지는 산구절초 추출물
    39.
    发明授权
    숙취 해소 및 항산화 활성을 가지는 산구절초 추출물 失效
    枸杞子提取物除去抗氧化活性

    公开(公告)号：KR100758266B1

    公开(公告)日：2007-09-13

    申请号：KR1020060034575

    申请日：2006-04-17

    Applicant: 한국과학기술연구원

    Inventor： 양현옥 ,  문길주 ,  이샛별 ,  김수남 ,  유지혜 ,  차광현 ,  노주원 ,  정상훈 ,  김영주 ,  서종택 ,  김수정

    IPC: A61K36/287 ,  A61P25/32

    CPC classification number: A61K36/287

    Abstract: Extract of Chrysanthemum zawadskii Herbich having hangover-removing and anti-oxidant activity is provided to promote in vivo alcohol metabolism and reduce blood alcohol concentration and acetaldehyde concentration by increasing activity of alcohol dehydrogenase and acetaldehyde dehydrogenase, and remove radicals without side effects. Extract of Chrysanthemum zawadskii Herbich having hangover-removing and anti-oxidant activity is prepared by extracting Chrysanthemum zawadskii Herbich with water, C1-C3 lower alcohol including methanol or ethanol or a mixed solvent thereof for 2-4 hours. A composition for removing hangover comprises 0.0001-50 wt.%, preferably 0.01-5 wt.% of the extract of Chrysanthemum zawadskii Herbich, wherein the composition is a health food composition.

    Abstract translation: 提供具有脱毒和抗氧化活性的菊花提取物，通过增加醇脱氢酶和乙醛脱氢酶的活性，去除自由基而不引起副作用，提供体内酒精代谢，降低血液酒精浓度和乙醛浓度。 通过用水，C1-C3低级醇（包括甲醇或乙醇）或其混合溶剂提取菊花（Chrysanthemum zawadskii Herbich）或其混合溶剂2-4小时制备具有宿醉去除和抗氧化活性的菊花提取物。 用于去除宿醉的组合物包含菊苣菊苣提取物的0.0001-50重量％，优选0.01-5重量％，其中所述组合物是保健食品组合物。

    찰콘 유도체를 포함하는 시신경 보호용 조성물
    40.
    发明授权
    찰콘 유도체를 포함하는 시신경 보호용 조성물 有权

    公开(公告)号：KR102231354B1

    公开(公告)日：2021-03-24

    申请号：KR1020200061761

    申请日：2020-05-22

    Applicant: 한국과학기술연구원

    Inventor： 이재욱 ,  김동회 ,  김경아 ,  권학철 ,  정상훈 ,  배애님

    IPC: A61K31/12 ,  A23L33/10 ,  A61P27/02

    Abstract: 본명세서는찰콘유도체를포함하는망막세포및 시신경보호용조성물에관한것으로서, 본발명의일 측면에따른특정화학식찰콘유도체, 이의이성질체, 이의약학적으로허용가능한염, 이의수화물, 또는이의용매화물을포함하는조성물은시신경보호및 시신경세포사멸억제효과가뛰어나므로, 관련질환을효과적으로예방, 개선및 치료하는새로운대안이될 것이고, 나아가상기조성물을이용하여해당환자의복지개선및 관련산업발전에기여할수 있다.

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