公开(公告)号：KR101151295B1

公开(公告)日：2012-06-19

申请号：KR1020090109947

申请日：2009-11-13

Applicant: 한국식품연구원

Inventor： 김혜영 ,  김동현 ,  이영경 ,  한찬규 ,  황진택 ,  이영철 ,  민성원 ,  김경 ,  박민

IPC: C12N1/20 ,  A23L19/00 ,  A23L2/72

Abstract: PURPOSE: A Pediococcus pentosaceus K-641(KFCC11463P) is provided to convert ginsenoside of low bioavailability to ginsenoside of high bioavailability and to improve glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-641(KFCC11463P) is used for fermenting ginseng. A method for preparing ginseng fermentation extract comprises: a step of fermenting a suspension of ginseng power with Pediococcus pentosaceus K-641(KFCC11463P) at 35-37 degrees Celsius for 3-10 days to obtain a fermentation; a step of extracting the fermentation with a solvent of ethanol, spirit, or butanol; and a step of filtering the extract.

公开(公告)号：KR101072834B1

公开(公告)日：2011-10-14

申请号：KR1020070138273

申请日：2007-12-27

Applicant: 한국식품연구원

Inventor： 이영철 ,  김혜영 ,  노정해 ,  이영경 ,  황진택 ,  조장원 ,  김경 ,  박민

IPC: A61K36/258 ,  A61K36/074 ,  A61P3/10

Abstract: 본발명은인삼을영지버섯(Ganoderma lucidum KCTC 6532) 균사체로발효시켜서제조된혈당강하용다당체분획물에관한것으로서, 상기혈당강하용다당체분획물은인삼을영지버섯균사체로발효하는단계; 발효물을증류수로열수추출한후 여과하는단계및 여과액과주정을혼합하여다당체분획물의침전물을얻는단계를거쳐제조된다. 이다당체분획물은혈당강하효과가우수하여공복혈당장애자, 내당능장애자, 당뇨병전단계로진단받은자, 당뇨병환자의치료에효과가있다.

公开(公告)号：KR1020110058515A

公开(公告)日：2011-06-01

申请号：KR1020090115334

申请日：2009-11-26

Applicant: 한국식품연구원

Inventor： 김혜영 ,  김동현 ,  이영경 ,  한찬규 ,  황진택 ,  이영철 ,  민성원 ,  김경 ,  박민

IPC: C12N1/20 ,  C12P1/04 ,  A61K31/70 ,  A23L19/00

Abstract: PURPOSE: A ginseng fermentation extract using a novel Pediococcus pentosaceus K-51 is provided to enhance insulin secretion and to treat diabetes. CONSTITUTION: A novel Pediococcus pentosaceus K-51(KFCC11465P) is able to ferment ginseng. A method for preparing a ginseng fermentation extract comprises: a step of fermenting ginseng powder with Pediococcus pentosaceus K-51(KFCC11465P) at 35-37 degrees Celsius for 3-10 days to obtain fermentation; and a step of filtering the fermentation using ethanol, spirit, or butanol at 60-80 degrees Celsius for 2-4 hours. A pharmaceutical formulation for enhancing insulin secretion contains the ginseng fermentation extract.

Abstract translation: 目的：提供一种人参发酵提取物，使用新型戊糖片球菌K-51来增强胰岛素分泌和治疗糖尿病。 构成：一种新型戊糖片球菌K-51（KFCC11465P）能够发酵人参。 制备人参发酵提取物的方法包括：在35-37摄氏度下将人参粉末与戊糖片球菌K-51（KFCC11465P）发酵3-10天以获得发酵的步骤; 以及在60-80摄氏度下使用乙醇，精油或丁醇过滤发酵2-4小时的步骤。 用于增强胰岛素分泌的药物制剂含有人参发酵提取物。

公开(公告)号：KR1020110053116A

公开(公告)日：2011-05-19

申请号：KR1020090109942

申请日：2009-11-13

Applicant: 한국식품연구원

Inventor： 김혜영 ,  김동현 ,  이영경 ,  한찬규 ,  황진택 ,  이영철 ,  민성원 ,  김경 ,  박민

IPC: C12N1/20 ,  A23L19/00 ,  A23L2/72

Abstract: PURPOSE: A novel Pediococcus pentosaceus K-65(KFCC11462P) and a method for preparing a ginseng fermentation using the same are provided to improve and maintain glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-65(KFCC11462P) is used for fermenting ginseng. A method for preparing ginseng fermentation extract comprises: a step of fermenting ginseng with Pediococcus pentosaceus K-65(KFCC11462P) at 35-37°C for 3-10 days to obtain a fermentation; a step of extracting with a solvent such as ethanol, spirit, or butanol at 60°C-80°C for 2-4 hours; and a step of filtering the extract. A pharmaceutical composition or health food for maintaining or improving glucose homeostasis contains the ginseng fermentation extract.

Abstract translation: 目的：提供一种新型戊糖片球菌K-65（KFCC11462P）及其制备人参发酵方法，以改善和维持葡萄糖体内平衡。 构成：一种新型戊酸球菌K-65（KFCC11462P）用于发酵人参。 一种人参发酵提取物的制备方法，其特征在于：在35-37℃下将戊糖片球菌K-65（KFCC11462P）人参发酵3-10天，得到发酵的步骤; 用溶剂如乙醇，精油或丁醇在60℃-80℃下萃取2-4小时的步骤; 以及过滤提取物的步骤。 用于维持或改善葡萄糖体内平衡的药物组合物或保健食品含有人参发酵提取物。

公开(公告)号：KR1020100054428A

公开(公告)日：2010-05-25

申请号：KR1020080113359

申请日：2008-11-14

Applicant: 한국식품연구원

Inventor： 김혜영 ,  김동현 ,  이영철 ,  이영경 ,  민성원 ,  김경 ,  박민

IPC: C12P1/02 ,  A61K36/258

CPC classification number: A61K36/258 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2124

Abstract: PURPOSE: An extract manufactured by fermenting ginseng or ginseng extract with lactobacillus is provided to maintain homeostasis and to be used in treating diabetes. CONSTITUTION: A method for manufacturing ginseng fermentation extract for improving glucose homeostasis comprises: a step of suspending ginseng powder in purified water; a step of fermenting ginseng powder-suspended liquid with lactobacillus; a step of extracting the fermented material with extraction solvent; and a step of decompressing and freeze-drying. The lactobacillus is Lactobacillus gasseri KCTC 3163. The extraction solvent is ethanol or butanol.

Abstract translation: 目的：提供通过用乳杆菌发酵人参或人参提取物制成的提取物，以维持体内平衡并用于治疗糖尿病。 构成：人参发酵提取物改善葡萄糖体内稳态的方法，包括：将人参粉末悬浮于纯化水中的步骤; 用乳杆菌发酵人参粉末悬浮液的步骤; 用提取溶剂萃取发酵物料的步骤; 和减压和冷冻干燥的步骤。 乳酸杆菌是加氏乳杆菌KCTC 3163.提取溶剂是乙醇或丁醇。