公开(公告)号：NO20010298L

公开(公告)日：2001-01-18

申请号：NO20010298

申请日：2001-01-18

Applicant: ABBOTT LAB

Inventor： BAUER JOHN F ,  SALEKI-GERHARDT AZITA ,  NARAYANAN BIKSHANDARKOIL A ,  CHEMBURKAR SANJAY R ,  PATEL KETAN ,  SPIWEK HARRY O ,  BAUER PHILIP E ,  ALLEN KIMBERLY A

IPC: A61K31/426 ,  A61K31/427 ,  A61P31/18 ,  A61P37/04 ,  C07D277/24 ,  C07D277/28 ,  C07D277/30 ,  C07D277/36 ,  C07D277/40 ,  C07D277/42 ,  C07D417/12 ,  C07D417/00

Abstract: This Application concerns the use of Form II crystalline ritonavir as a pharmaceutical agent, as well as methods of preparing pharmaceutical compositions, which methods employ Form II crystalline ritonavir. The Application further concerns methods for obtaining Form I crystalline ritonavir, which methods employ Form II crystalline ritonavir.

公开(公告)号：GR3033791T3

公开(公告)日：2000-10-31

申请号：GR20000401490

申请日：2000-06-27

Applicant: ABBOTT LAB

Inventor： CHEMBURKAR SANJAY R ,  PATEL HEMANTKUMAR H ,  SAWICK DAVID P ,  THOMAS ALBERT V

IPC: C07C43/29 ,  C07C43/295 ,  C07C273/18 ,  C07C275/64

公开(公告)号：HU227540B1

公开(公告)日：2011-08-29

申请号：HU0103823

申请日：1999-07-19

Applicant: ABBOTT LAB

Inventor： BAUER JOHN F ,  SALEKI-GERHARDT AZITA ,  NARAYANAN BIKSHANDARKOIL A ,  CHEMBURKAR SANJAY R ,  PATEL KETAN ,  SPIWEK HARRY O ,  BAUER PHILIP E ,  ALLEN KIMBERLY A

IPC: C07D277/24 ,  A61K31/425 ,  A61K31/426 ,  A61K31/427 ,  A61P31/18 ,  A61P37/04 ,  C07D277/28 ,  C07D277/30 ,  C07D277/36 ,  C07D277/40 ,  C07D277/42 ,  C07D417/12

Abstract: This Application concerns the use of Form II crystalline ritonavir as a pharmaceutical agent, as well as methods of preparing pharmaceutical compositions, which methods employ Form II crystalline ritonavir. The Application further concerns methods for obtaining Form I crystalline ritonavir, which methods employ Form II crystalline ritonavir.

公开(公告)号：CA2416955C

公开(公告)日：2011-04-26

申请号：CA2416955

申请日：2001-08-29

Applicant: ABBOTT LAB

Inventor： CHEMBURKAR SANJAY R ,  PATEL KETAN M ,  SPIWEK HARRY O

IPC: C07D239/10 ,  C07B53/00 ,  C07D403/06 ,  C07D521/00

Abstract: The instant invention provides processes and intermediates employed in the synthesis of ((2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)-amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2-onyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane and analogs thereof.

公开(公告)号：SI1418174T1

公开(公告)日：2009-08-31

申请号：SI9931030

申请日：1999-07-19

Applicant: ABBOTT LAB

Inventor： BAUER JOHN F ,  SALEKI-GERHARDT AZITA ,  CHEMBURKAR SANJAY R ,  PATEL KETAN ,  SPIWEK HARRY O

IPC: C07D277/00 ,  A61K31/00 ,  A61K31/426 ,  A61K31/427 ,  A61P31/18 ,  A61P37/04 ,  C07D277/24 ,  C07D277/28 ,  C07D277/30 ,  C07D277/36 ,  C07D277/40 ,  C07D277/42 ,  C07D417/12

公开(公告)号：DE60327709D1

公开(公告)日：2009-07-02

申请号：DE60327709

申请日：2003-10-22

Applicant: ABBOTT LAB

Inventor： BENNANI YOUSSEF L ,  CHANG SOU-JEN ,  CHEMBURKAR SANJAY R ,  DART MICHAEL J ,  FERNANADO DILINIE P ,  GRIEME TIMOTHY A

IPC: A61K31/19 ,  A61K31/33 ,  A61K31/397 ,  A61K31/401 ,  A61K31/495 ,  A61K31/537 ,  A61K31/54 ,  A61K31/55 ,  A61P25/08 ,  C07C61/13 ,  C07C61/135 ,  C07C61/29 ,  C07C69/753 ,  C07C233/58 ,  C07C237/22 ,  C07C237/24

Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.

公开(公告)号：DK1313712T3

公开(公告)日：2007-09-10

申请号：DK01966367

申请日：2001-08-29

Applicant: ABBOTT LAB

Inventor： CHEMBURKAR SANJAY R ,  SPIWEK HARRY O ,  PATEL KETAN M

IPC: C07D239/10 ,  C07B53/00 ,  C07D403/06 ,  C07D521/00

Abstract: The instant invention provides processes and intermediates employed in the synthesis of ((2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)-amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2-onyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane and analogs thereof.

公开(公告)号：DE60128367D1

公开(公告)日：2007-06-21

申请号：DE60128367

申请日：2001-08-29

Applicant: ABBOTT LAB

Inventor： CHEMBURKAR SANJAY R ,  PATEL KETAN M ,  SPIWEK HARRY O

IPC: C07D239/10 ,  C07B53/00 ,  C07D403/06 ,  C07D521/00

Abstract: The instant invention provides processes and intermediates employed in the synthesis of ((2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)-amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2-onyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane and analogs thereof.

公开(公告)号：CA2604408A1

公开(公告)日：2006-10-26

申请号：CA2604408

申请日：2006-04-19

Applicant: ABBOTT LAB

Inventor： PRUYNE JULIE J ,  ULREY STEPHEN S ,  CHEMBURKAR SANJAY R

IPC: C07D498/22

Abstract: Methods for separating K-252a from the cell mass of its parent fermentation broth are disclosed.

公开(公告)号：CA2502323A1

公开(公告)日：2004-05-06

申请号：CA2502323

申请日：2003-10-22

Applicant: ABBOTT LAB

Inventor： BENNANI YOUSSEF L ,  CHEMBURKAR SANJAY R ,  CHAMBERLIN STEVE A ,  WANG LEI ,  GUPTA ASHOK K ,  DART MICHAEL J ,  CHEN JINHUA

IPC: A61K31/16 ,  A61K31/33 ,  A61K31/397 ,  A61K31/54 ,  A61K31/55 ,  A61P25/06 ,  A61P25/08 ,  C07C233/08 ,  C07C233/58 ,  C07C233/60 ,  C07C233/63 ,  C07C237/22 ,  C07D233/24

Abstract: The present invention relates to the use of compounds of formula (I)for the treatment of a variety of disorders including, bu t not limited to, epilepsy , bipolar disorder, psychiatric disorders, migraine, pain, neuroprotection, an d movement disorders.